Test Price
2,800 AED✅ Home Collection Available
XPR1 Gene Sequencing – Idiopathic Basal Ganglia Calcification Type 6 in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO-Accredited NGS Processing with Sanger Confirmation.
Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
Clinical Guidance: Pre- and Post-Test Genetic Counseling by DHA-licensed Consultant Medical Geneticist.
Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This test utilizes Next Generation Sequencing (NGS) with orthogonal Sanger validation to identify pathogenic and likely pathogenic variants in the XPR1 gene, confirming idiopathic basal ganglia calcification type 6 (primary familial brain calcification). Results guide neurologists, pediatricians, and clinical geneticists in diagnosis, familial cascade screening, and clinical management.
| Feature | Our Test (XPR1 NGS) | Closest Alternative (Whole Exome Sequencing) |
|---|---|---|
| Diagnostic Precision | 99.9% sensitivity for XPR1 SNVs and indels | ~95% for known genes, may miss deep intronic or regulatory variants |
| Methodology | Targeted NGS + Sanger confirmation of all variants | Bead-based capture + NGS, no confirmatory Sanger |
| Turnaround Time | 3 – 4 Weeks | 6 – 8 Weeks |
Physician Insight & Safety Protocols
"Each XPR1 variant tells a distinct story about calcium regulation in the brain. This test provides a definitive molecular diagnosis for idiopathic basal ganglia calcification, but results must always be interpreted alongside clinical findings, imaging, and family history. Our role is to deliver clarity without causing unnecessary alarm — your neurologist and genetic counselor will guide all next steps."
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Safety Advisory
Do not discontinue, adjust, or initiate any prescribed medication based solely on genetic test results without explicit instruction from your treating physician. Abrupt changes may precipitate acute neurological or psychiatric events.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Inability to provide informed consent or lack of a legal guardian for minors; known interfering medications or conditions not disclosed during pre-test counseling.
- Emergency Red Flags: Acute onset of severe headache, seizures, loss of consciousness, or sudden exacerbation of movement disorders — seek emergency care immediately.
Patient FAQ & Clinical Guidance
1. What is XPR1 gene testing for basal ganglia calcification?
XPR1 gene sequencing identifies disease-causing mutations that lead to idiopathic basal ganglia calcification type 6, enabling precise diagnosis, familial risk assessment, and tailored neurological management. This test analyzes all coding regions and conserved splice sites of the XPR1 gene using Next Generation Sequencing with Sanger confirmation for every detected variant.
2. How should I prepare for the genetic test and what sample is needed?
Preparation includes a pre-test genetic counseling session to document your family pedigree, discuss implications of potential findings, and obtain informed consent. We accept whole blood (3–5 ml in EDTA tube), extracted DNA, or a dried blood spot on an FTA card — all collected via our ISO-certified VIP mobile phlebotomy service operating daily from 8 AM to 11 PM. Fasting is not required; continue all prescribed medications unless advised otherwise by your physician.
3. Will insurance cover this test and how long do results take?
Many UAE health insurers cover XPR1 gene sequencing when ordered by a neurologist or clinical geneticist; we verify your coverage directly via WhatsApp before sample collection. Results are delivered within 3 to 4 weeks from sample receipt, accompanied by a mandatory post-test counseling session to explain findings and outline next steps. Self-pay price is 2,800 AED.
UAE Regulatory & Data Privacy Adherence
This service complies with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields for genomic data security and confidentiality. All clinical testing safety and patient consent procedures follow Federal Decree-Law No. 4 of 2016 on Medical Liability. Genetic data is processed exclusively within our ISO 9001:2015 certified laboratory facility (Cert: INT/EGQ/2509DA/3139).
Clinical & Logistical Metadata
| Test Name | XPR1 Gene Sequencing – Idiopathic Basal Ganglia Calcification Type 6 |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 – 4 Weeks |
| Sample Type / Matrix | Whole Blood (EDTA), Extracted DNA, or FTA Card |
| Methodology Used | Next Generation Sequencing (NGS) with Sanger Confirmation |
| ICD-10-CM Code | G23.8, Z13.79, Z14.8 |
| LOINC Code | 82939-0 |
| DHA Facility License & Laboratory Address | License 1143 — Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians