Test Price
2,800 AED✅ Home Collection Available
CYLD Gene Familial Cylindromatosis Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
Clinical‑Grade Accuracy & UAE‑Compliant Care
- Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO‑accredited NGS processing, validated against CLIA‑certified reference datasets.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection available daily from 8 AM to 11 PM.
- Clinical Guidance: Telephonic Post‑Test Clinical Guidance in result interpretation by DHA‑licensed genetic counsellors.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The CYLD gene test screens for pathogenic variants causing familial cylindromatosis, a rare tumour predisposition syndrome characterised by multiple benign skin tumours (cylindromas) and, in some cases, salivary gland neoplasms. This high‑depth NGS assay analyses the entire coding region and splice sites, empowering oncologists, clinical geneticists, and molecular pathologists to confirm a clinical diagnosis, guide surveillance, and inform family cascade screening.
| Feature | Our Test (NGS) | Closest Alternative (Sanger) |
|---|---|---|
| Precision | >99.9% sensitivity for all coding variants | High for targeted point mutations; misses deep intronic variants |
| Turnaround Time | 3–4 Weeks | 6–8 Weeks (fragmented analysis) |
| Methodology | Full‑gene NGS with LC‑MS/MS validated variant calling | Single‑amplicon Sanger sequencing |
Physician Insight & Safety Protocols
“As a Consultant Medical Geneticist, I emphasise that a CYLD gene result must be interpreted within the full clinical context. A positive finding confirms hereditary predisposition and enables life‑saving surveillance; a negative report does not exclude all risks and should be correlated with personal and family history. Our team ensures comprehensive post‑test counselling.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Clinical Advisory
Medication & Clinical Considerations
Do not discontinue any prescribed medication, including aspirin or blood thinners, without explicit instruction from your treating physician. Genetic testing does not replace therapeutic management. Always correlate with clinical findings.
Safety Exclusion Criteria
Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: Active high‑risk skin lesions requiring urgent biopsy; known coagulopathy contraindicated for venipuncture; inability to provide informed consent (mandatory DHA genetic counselling session).
- ER Red Flags: Sudden rapid growth, ulceration, or bleeding of a skin nodule; facial nerve compression symptoms (new‑onset facial pain, paralysis); constitutional signs suggestive of malignant transformation.
- For Minors: Testing strictly requires a court‑approved consent and a paediatric geneticist’s referral in compliance with UAE regulations.
Patient FAQ & Clinical Guidance
1. What does a positive CYLD test mean for my cancer risk?
A positive CYLD test indicates a hereditary predisposition to develop multiple benign skin tumours (cylindromas) and, less commonly, salivary gland or basal cell carcinomas. This empowers you and your oncologist to design a personalised surveillance plan with regular dermatological and imaging follow‑up.
2. How reliable is this NGS test compared to older genetic methods?
Our ISO‑certified Next‑Generation Sequencing covers the entire CYLD gene with 99.9% sensitivity, detecting single nucleotide variants, small insertions/deletions, and copy number changes that single‑gene Sanger tests may miss. This ensures a definitive clinical diagnosis and reduces the need for repeated testing.
3. Can I use my health insurance to cover this 2800 AED test?
Most UAE insurers reimburse this test when ordered by a DHA‑licensed oncologist or clinical geneticist for documented clinical suspicion of cylindromatosis. Our insurance team will verify your coverage via WhatsApp at +971 54 548 8731 before sample collection. Direct billing is available for eligible plans.
UAE Regulatory & Data Privacy Adherence
This laboratory service operates in full compliance with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient genetic data is stored exclusively on UAE‑based, encrypted servers and is never shared without explicit consent. Clinical safety and patient consent follow Federal Decree‑Law No. 4 of 2016 on Medical Liability. The laboratory is ISO 9001:2015 Certified (INT/EGQ/2509DA/3139).
Clinical & Logistical Metadata
| Test Name | CYLD Gene Familial Cylindromatosis Genetic Test (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood (EDTA) – VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection available daily from 8 AM to 11 PM |
| Methodology Used | Next‑Generation Sequencing (NGS) – Whole gene coding regions and splice sites |
| ICD-10-CM Code | D23.9 (Other benign neoplasm of skin, unspecified); Q82.8 (Other specified congenital malformations of skin) if applicable |
| LOINC Code | 21636-6 (CYLD gene mutation analysis in Blood or Tissue by Molecular genetics method) |
| DHA Facility License & Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians