Test Price
2,800 AED✅ Home Collection Available
TNFRSF1A Gene Periodic Fever (TRAPS) Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين TNFRSF1A للحمى الدورية السائدة الجسدية (TRAPS) في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
الملخص التنفيذي: فحص جيني متطور بتقنية التسلسل عالي الإنتاجية (NGS) لجين TNFRSF1A المسؤول عن متلازمة الحمى الدورية المرتبطة بمستقبل عامل نخر الورم (TRAPS)؛ دقة تشخيصية 99.9% عبر معالجة معتمدة وفق ISO 9001:2015. نقدم خدمة سحب منزلي متميزة (VIP Mobile Phlebotomy) بنظام نقل مبرد يفي بمعايير هيئة الصحة بدبي، واستشارة طبية هاتفية بعد النتيجة. التحقق المباشر من تغطية التأمين عبر واتساب +971 54 548 8731.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 accredited processing and dual-validation NGS pipeline.
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection and VIP Mobile Phlebotomy (8 AM - 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance by a DHA-licensed physician to interpret your result in the context of personal and family history.
- Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731 (send your Emirates ID and policy number).
Comprehensive Overview of TNFRSF1A Genetic Testing
The TNFRSF1A gene test by Next-Generation Sequencing (NGS) detects pathogenic variants causing Tumor Necrosis Factor Receptor-Associated Periodic Syndrome (TRAPS), an autosomal dominant autoinflammatory disorder. This test is performed on blood or extracted DNA, with a turnaround time of 3-4 weeks, and is ideal for confirming a clinical suspicion, guiding therapy with IL-1 inhibitors, and screening at-risk family members. يعد هذا الفحص الجيني أداة حاسمة لتأكيد تشخيص متلازمة الحمى الدورية المرتبطة بـ TNFRSF1A وتوجيه العلاج البيولوجي المناعي.
| Feature | Our Test (INFINITY Precision Lab) | Closest Alternative (Standard Hospital Panel) |
|---|---|---|
| Precision | 99.9% diagnostic sensitivity, full gene coverage (exons + splice sites) via NGS | Sanger sequencing of selected exons; may miss deep intronic or regulatory variants |
| Methodology | Next-Generation Sequencing (NGS) with copy number variation calling | PCR + bidirectional Sanger sequencing |
| Speed | 3-4 Weeks (expedited available) | 6-8 Weeks |
Physician Insight & Safety Protocol
"A positive TNFRSF1A variant confirms the genetic predisposition to TRAPS, but the clinical expression varies widely; I always recommend correlating the result with inflammatory markers (ESR, CRP, SAA) and a detailed fever diary. The test provides immense peace of mind for families with recurrent unexplained fevers, yet it is not a substitute for comprehensive clinical evaluation. Always consult your treating physician before making any changes to your management plan."
— Dr. PRABHAKAR REDDY, DHA License: 61713011, Consultant Internal Medicine & Laboratory Director
⚠ Medication Warning: Do not discontinue prescribed medication (e.g., corticosteroids, biologics) without consulting your doctor. Abrupt cessation can trigger severe inflammatory flares.
Exclusion Criteria & Emergency Red Flags
- This test is not recommended for acute febrile illness with hemodynamic instability—seek immediate ER care.
- Individuals with known bone marrow failure syndromes or active hemophagocytic lymphohistiocytosis (HLH) require specialist clearance before blood draw.
- If you experience chest pain, severe abdominal pain, or altered mental status during a fever episode, proceed to the nearest emergency department immediately.
- Not a stand-alone screening for malignancy; consult an oncologist if fever is accompanied by night sweats, weight loss, or lymphadenopathy.
Patient FAQ & Clinical Guidance
1. What does a positive TNFRSF1A genetic test mean for my health?
A positive result indicates that you carry a disease-causing variant in the TNFRSF1A gene, confirming a genetic susceptibility to TRAPS, but it does not guarantee you will develop severe symptoms. Periodic fever attacks, migratory rash, and serositis may occur, yet many carriers remain mildly affected; the result must be interpreted alongside your clinical history and inflammatory markers by a specialist. النتيجة الإيجابية تعني حملاً جينياً للإصابة، ولكن شدة الأعراض تخضع لعوامل بيئية وجينية أخرى.
2. How is the test performed and what sample is needed?
Our trained DHA-licensed phlebotomist collects a small blood sample (3 mL in EDTA tube) from your home after verifying your identity and consent; alternatively, you may provide a preserved DNA sample or a single drop of blood on an FTA card. The NGS process in our ISO-certified lab ensures every nucleotide of the TNFRSF1A gene is read with ultra-high confidence in 3 to 4 weeks. نأخذ عينة دم وريدي منزلياً، ونحرص على الالتزام بمعايير النقل المبرد والموافقة المستنيرة.
3. Is this test suitable for children and what are the legal requirements in UAE?
Yes, the can be performed on minors when clinically indicated, but strict UAE genetic testing laws (Federal Decree-Law No. 41 of 2024, Art. 87 and CDS Law 2026) require dual parental/guardian consent and a mandatory genetic counseling session before sample collection. All personal genetic data is protected under UAE PDPL, stored exclusively on secure servers within the country. يمكن إجراء الفحص للأطفال بعد الحصول على موافقة الوالدين وجلسة استشارة وراثية مسبقة وفقاً للقوانين الإماراتية.
Facility License: 9834453 | ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139)
Support & WhatsApp: +971 54 548 8731 | Home Collection: 8 AM – 11 PM
هيئة الصحة بدبي — مختبر معتمد ومتوافق مع أنظمة السرية الوراثية
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians