Test Price
2,800 AED✅ Home Collection Available
TMEM67 Gene (Meckel Syndrome Type 3) Genetic Test in UAE | 2800 AED
Executive Summary & Core Metrics
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
Clinical Guidance: Complimentary Telephonic Post-Test Clinical Guidance for result interpretation by our DHA-licensed clinical team.
Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The TMEM67 gene NGS test detects pathogenic variants causing Meckel syndrome type 3 (MKS3), a severe autosomal recessive ciliopathy affecting the kidneys, liver, and central nervous system. In the UAE, where consanguinity rates are elevated, this test provides definitive molecular confirmation for early diagnosis, carrier screening, and informed reproductive planning.
| Feature | Our Test (TMEM67 NGS) | Closest Alternative (Single‑gene Sanger) |
|---|---|---|
| Precision | >99.9% sensitivity for exonic & splice‑site variants | ~95% for targeted regions, no copy‑number detection |
| Method | Next‑Generation Sequencing (NGS) with full bioinformatics analysis | Sanger sequencing of coding exons only |
| Speed | 3 to 4 Weeks | 4 to 6 Weeks |
Physician Insight & Safety Protocols
“As a clinical geneticist, I emphasize that a positive TMEM67 result must be correlated with renal and hepatic ultrasound findings, as well as family history. Patients carrying a variant may be asymptomatic carriers; this test is not a standalone diagnostic but a precise molecular tool that requires expert interpretation. Always review results with your referring clinical geneticist, pediatric nephrologist, or hepatologist.” — Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403.
Advisory: Medication Continuity
Medication Advisory
Do not discontinue prescribed medication without consulting your doctor.
Safety Exclusion Criteria & Red Flags
- Hemodynamic instability or acute decompensation requiring urgent care prior to sample collection.
- Recent (< 2 weeks) major surgery or active severe infection that may delay elective genetic testing.
- Inability to provide informed consent (for minors, parental/guardian consent is mandatory as per Federal Decree-Law No. 4 of 2016 on Medical Liability).
- Emergency Red Flags: Sudden onset of severe abdominal pain, projectile vomiting, or seizures in a child with suspected MKS3 – proceed to ER immediately.
Patient FAQ & Clinical Guidance
1. What is the clinical utility of the TMEM67 NGS test?
This test definitively confirms Meckel syndrome type 3, differentiates it from other ciliopathies, and guides perinatal management and family screening plans. A positive result enables targeted ultrasound surveillance and timely intervention for renal and hepatic complications. Interpretation must be done by a certified clinical geneticist in conjunction with imaging.
2. How should I prepare for the blood sample collection?
No fasting is required; simply provide a whole blood sample in an EDTA tube, extracted DNA, or a single drop on an FTA card. Our VIP mobile phlebotomist visits your home between 8 AM and 11 PM, and the sample is transported in a validated cold‑chain container. Avoid strenuous exercise 2 hours prior to draw to prevent hemolysis.
3. Is this covered by insurance and is it confidential?
Many UAE insurers reimburse genetic testing when medically necessary; our team verifies your coverage directly via WhatsApp before scheduling. All patient data is protected under Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields, with strict anonymization protocols.
UAE Regulatory & Data Privacy Adherence
TMEM67 genetic testing at DNA Labs UAE is conducted in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient data is handled with strict confidentiality, processed in ISO‑certified facilities, and used solely for clinical diagnostic purposes. All sample handling and reporting adhere to the highest standards of data security and ethical practice as mandated by the Dubai Health Authority.
Clinical & Logistical Metadata
| Test Name | TMEM67 Gene (Meckel Syndrome Type 3) Genetic Test – NGS |
| Price (AED) | 2,800 |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type / Matrix | Whole Blood (EDTA), Extracted DNA, or FTA Card Spot |
| Methodology Used | Next‑Generation Sequencing (NGS) – Full Gene Sequencing |
| ICD-10-CM Code | Q61.9 |
| LOINC Code | 81316-6 |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians