Test Price
2,800 AED✅ Home Collection Available
SYP Gene (X-Linked Intellectual Disability Type 96) Genetic Test in UAE | Price 2800 AED | DNA Labs UAE
Executive Summary & Core Metrics
This targeted genetic test sequences the entire coding region of the SYP gene using Next‑Generation Sequencing (NGS) to detect pathogenic variants associated with X‑linked intellectual disability type 96. Processed under ISO 9001:2015 accredited protocols at our DHA-licensed facility, it guarantees 99.9% diagnostic sensitivity for point mutations and small insertions or deletions.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Telephonic Post‑Test Clinical Interpretation and Genetic Counseling included.
- Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The SYP gene provides instructions for synaptophysin, a protein essential for synaptic vesicle function and neurotransmitter release. Pathogenic variants in this gene disrupt neuronal signaling, leading to intellectual disability, developmental delay, and epilepsy. This NGS-based test offers comprehensive coverage of the SYP coding exons and flanking splice sites, providing a definitive molecular diagnosis for X-linked intellectual disability type 96.
| Feature | Our Test (NGS Panel) | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Diagnostic Precision | 99.9% analytical sensitivity for point mutations & small indels | ~95% – limited detection of mosaicism |
| Method | Next‑Generation Sequencing (NGS) | Capillary electrophoresis Sanger |
| Turnaround Time | 3 – 4 Weeks | 4 – 6 Weeks |
| Coverage | Entire SYP coding region + splice sites | Single amplicon, miss large deletions |
Physician Insight & Safety Protocols
“Interpreting SYP gene variants requires integrating molecular findings with detailed clinical phenotyping and family segregation studies. While a definitive pathogenic variant confirms the diagnosis of X-linked intellectual disability type 96, a negative result does not exclude all genetic etiologies. We prioritize comprehensive pre- and post-test counseling to ensure patients and families fully understand the implications for management, recurrence risk, and reproductive options.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA ID: 9294403
Medication Advisory
Do not discontinue any prescribed medications without consulting your physician. Genetic testing results may influence medication management; our consultants will guide you through any necessary adjustments.
Safety Exclusion Criteria & ER Red Flags
- Exclusion Criteria: Active infection, severe coagulopathy, or concurrent participation in conflicting clinical trials may postpone sample collection.
- Emergency Red Flags: Seek immediate medical attention for new‑onset seizures, acute loss of developmental milestones, or rapid neurological decline (exceedingly rare post‑phlebotomy).
- Paediatric Consideration: Minors must be accompanied by a legal guardian; consent is obtained in accordance with Federal Decree-Law No. 4 of 2016 on Medical Liability.
Patient FAQ & Clinical Guidance
1. What is the SYP gene test for?
This test analyzes the SYP gene using next-generation sequencing (NGS) to identify pathogenic variants responsible for X-linked intellectual disability type 96. It aids in confirming a clinical diagnosis, guiding early intervention strategies, and assessing carrier risk for family planning.
2. How is the SYP gene test different from other intellectual disability panels?
Unlike broad intellectual disability panels that analyze dozens of genes simultaneously, this targeted NGS test focuses exclusively on the SYP gene, offering deeper coverage, higher sensitivity for coding region variants, and faster interpretation. It is ideal when clinical presentation strongly suggests SYP-related X-linked inheritance.
3. What type of sample is required, and how should it be collected?
A peripheral whole blood sample (3–5 mL in an EDTA tube) is the preferred specimen. Alternatively, extracted DNA or an FTA card can be used. Our VIP Mobile Phlebotomy service ensures a temperature-controlled cold-chain collection at your home between 8 AM and 11 PM daily.
4. What is the turnaround time for receiving results?
Results are typically available within 3 to 4 weeks from the date the sample is received at our laboratory. A comprehensive clinical report will be provided, along with a telephonic consultation to explain the findings and their implications.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE strictly adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent protocols are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability. Our facility is licensed by the Dubai Health Authority (DHA License No. 1143).
Clinical & Logistical Metadata
| Test Name | SYP Gene (X-Linked Intellectual Disability Type 96) – NGS Sequencing |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole Blood (3–5 mL in EDTA), Extracted DNA, or FTA Card |
| Methodology Used | Next‑Generation Sequencing (NGS) – Whole Gene Plus Flanking Splice Sites |
| ICD-10-CM Code | F78 |
| LOINC Code | 81305-3 |
| DHA Facility License & Lab Address | DHA License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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