Test Price
2,800 AED✅ Home Collection Available
SFXN4 Gene Combined Oxidative Phosphorylation Deficiency Type 18 Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل تسلسل الجين SFXN4 لكشف نقص الفسفرة التأكسدية المركب من النوع 18 في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
ضمان الدقة: حساسية تشخيصية بنسبة 99.9% عبر معالجة معتمدة وفق ISO 9001:2015. خدمة منزلية درجة المستشفى: جمع عينات عبر سلسلة تبريد معتمدة و فصد متنقل VIP. إرشاد سريري: جلسة استشارة هاتفية بعد الفحص لتفسير النتائج. التأمين: التحقق من التغطية التأمينية المباشرة عبر واتساب 971545488731+.
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO-Accredited Processing. Premium Logistics: Hospital‑Grade Home Collection with Certified Cold‑Chain & VIP Mobile Phlebotomy. Clinical Guidance: Telephonic Post‑Test Clinical Discussion. Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Overview
This single‑gene NGS test analyses the entire coding region of SFXN4 to confirm or exclude biallelic pathogenic variants causing Combined Oxidative Phosphorylation Deficiency Type 18, a severe mitochondrial disorder. The assay is optimized for UAE ordering clinicians, providing a definitive diagnosis in 3–4 weeks with pre‑ and post‑test genetic counselling integration.
| Feature | Our SFXN4 NGS Test (Gold Standard) | Closest Alternative (Whole Exome Sequencing) |
|---|---|---|
| Precision | Targeted full SFXN4 coverage with >99% analytical sensitivity & specificity | Moderate depth; may miss deep intronic or copy‑number variants |
| Method | Clinical‑grade NGS with orthogonal Sanger confirmation of all pathogenic variants | Broad genomic sweep with incidental findings and complex variant interpretation |
| Speed | 3–4 weeks from sample arrival | Often 8–12 weeks |
| Cost (AED) | 2,800 | 3,500 – 5,000 |
Physician Insight & Safety Protocol
“As a physician, I understand how overwhelming the search for a genetic diagnosis can be. This SFXN4 test delivers precise molecular clarity, but the results must always be interpreted alongside your clinical picture, neurological examination, and family history. Please remember, genetic information is one vital piece of your health puzzle – not a stand‑alone verdict.”
— Dr. Prabhakar Reddy, DHA License: 61713011, Senior Consultant in Clinical Genomics
Clinical Safety & Exclusion Criteria
- Informed Consent Mandate: Minors require legal guardian consent per UAE CDS Law (2026). Adults with impaired decision‑making capacity cannot be tested without a legally authorized representative.
- Coagulopathy/Recent Transfusion: Severe bleeding disorders or blood transfusion within 4 weeks may compromise DNA integrity; physician clearance required before blood draw.
- Medication Warning: Do not discontinue any prescribed medication without consulting your treating physician. No routine supplements or drugs interfere with this genetic test.
- Emergency Red Flags: If you develop new or worsening seizures, loss of consciousness, acute muscle weakness, or respiratory distress before your scheduled collection, seek immediate emergency medical care.
Patient FAQ & Clinical Guidance
1. How is the SFXN4 NGS test performed and what sample is required?
We accept a simple blood sample (5 ml in EDTA tube), extracted DNA, or a single blood drop on an FTA card. The sample is processed using next‑generation sequencing that reads the entire SFXN4 gene with >99% coverage, and any variant found is confirmed by the gold‑standard Sanger method to ensure 100% accuracy. No fasting is necessary unless additional metabolic tests are ordered.
نقبل عينة دم بسيطة (5 مل في أنبوب EDTA)، أو حمض نووي مستخلص، أو قطرة دم واحدة على بطاقة FTA. تُحلل العينة بتقنية التسلسل الجيني من الجيل التالي التي تغطي جين SFXN4 بالكامل، ويتم تأكيد أي طفرة مكتشفة بطريقة سانجر المرجعية لضمان الدقة الكاملة. لا يشترط الصيام.
2. What does a positive result mean and who should order this test?
A positive result means two disease‑causing mutations (one from each parent) were identified, confirming the diagnosis of Combined Oxidative Phosphorylation Deficiency Type 18. This should be ordered by a general physician, clinical geneticist, or dietitian after a detailed clinical history and pedigree chart. Genetic counselling is mandatory before testing to help you understand the implications for symptom management, family risk, and reproductive options.
تعني النتيجة الإيجابية اكتشاف طفرتين ممرضتين (واحدة من كل والد)، مما يؤكد تشخيص نقص الفسفرة التأكسدية المركب من النوع 18. يجب طلب الفحص من قبل طبيب عام أو اختصاصي تغذية بعد أخذ تاريخ سريري ورسم شجرة العائلة. الاستشارة الوراثية إلزامية قبل الفحص.
3. How does UAE law protect my genetic data and insurance coverage?
Your genetic data is protected under Federal Decree‑Law No. 41 of 2024 (Article 87) and the UAE Personal Data Protection Law (PDPL), ensuring full confidentiality. We process all samples in our ISO 9001:2015 accredited facility (Cert: INT/EGQ/2509DA/3139) with encrypted reporting. While many UAE insurers cover medically necessary genetic tests, we offer direct billing verification via WhatsApp at +971 54 548 8731 to confirm your coverage before booking. No data is shared with third parties without your explicit, documented consent.
بياناتك الجينية محمية بموجب القانون الاتحادي رقم 41 لسنة 2024 (المادة 87) وقانون حماية البيانات الشخصية، مما يضمن السرية التامة. نعالج العينات في مختبر معتمد ISO 9001:2015 مع تقارير مشفرة. نقدم خدمة التحقق المباشر من التغطية التأمينية عبر واتساب 971545488731+ قبل الحجز.
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توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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