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Test Price

2,800 AED

✅ Home Collection Available

SERPINE1 Gene (Plasminogen Activator Inhibitor Type 1) Genetic Test in UAE | 2,800 AED | 2026 DHA Guidelines

تحليل جين SERPINE1 (مثبط منشط البلازمينوجين من النوع 1) في الإمارات | 2,800 درهم | معتمد من هيئة الصحة بدبي

  • Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified Sequencing.
  • Premium Logistics: Hospital-Grade Home Collection with ISO-Certified Cold Chain, VIP Mobile Phlebotomy (8 AM – 11 PM).
  • Clinical Guidance: Telephonic Post-Test Result Interpretation by DHA-Licensed Genetic Counsellors.
  • Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731

ملخص تنفيذي

يضمن اختبار التسلسل الجيني للجيل التالي (NGS) لجين SERPINE1 دقة تشخيصية تبلغ 99.9% عبر مختبر معتمد بمعيار ISO 9001:2015. نقدم خدمة سحب عينات منزلية فاخرة تحت إشراف ممرضين متخصصين، مع استشارة وراثية هاتفية بعد الفحص. التحقق المباشر من تغطية التأمين عبر واتساب.

Test Overview & Clinical Relevance

يستهدف التحليل الجيني لجين SERPINE1 This next-generation sequencing (NGS) test analyzes the entire coding region of the SERPINE1 gene, which encodes plasminogen activator inhibitor-1 (PAI-1), a key regulator of fibrinolysis and vascular health. It identifies pathogenic variants associated with thrombotic and vascular disorders, enabling early risk stratification and personalized prevention strategies.

Feature Our SERPINE1 NGS Test Closest Alternative (Sanger Sequencing)
Diagnostic Precision >99.9% analytical sensitivity; complete exon coverage ~98% per amplicon; may miss deep intronic variants
Methodology Illumina NGS with proprietary bioinformatics, confirmed by Sanger validation Single-gene capillary electrophoresis
Turnaround Time 21–28 working days (with genetic counselling report) 15–20 working days (limited interpretation)

Clinical Expert Note & Safety Protocol

“A SERPINE1 genetic test provides a window into your body’s clotting-fibrinolytic balance, but it must be interpreted alongside your medical history and coagulation profile. As your physician, I emphasize that a negative result does not eliminate all vascular risk, and a positive finding should be discussed in a dedicated genetic counselling session before any lifestyle or therapeutic changes.”

— Dr. PRABHAKAR REDDY, DHA License: 61713011, Specialist Physician & Genetic Counsellor.

⚠ IMPORTANT MEDICATION WARNING:

Do not discontinue any prescribed antithrombotic, anticoagulant, or hormone therapy based on this genetic test result without first consulting your treating physician. Abrupt cessation can cause fatal thromboembolic events.

PATIENT SAFETY & EXCLUSION CRITERIA:

  • Acute thrombosis or uncontrolled bleeding within the last 4 weeks – postpone collection.
  • Known bone marrow transplant within 6 months; donor DNA may interfere.
  • Emergency red flags: Sudden severe chest pain, hemoptysis, or limb swelling requires immediate ER visit, not a scheduled test.

Patient FAQs & Clinical Guidance

1. How does this NGS test detect SERPINE1-related vascular risk?

Snippet Answer: Our NGS panel fully sequences the SERPINE1 gene, identifying all pathogenic variants associated with thrombophilia and vascular disease susceptibility with 99.9% sensitivity.

The test maps single nucleotide variants, small insertions/deletions, and copy number changes using dual capture probes, validated against reference genome GRCh38. Results classify variants as benign, likely pathogenic, or pathogenic following ACMG guidelines.

فحص جين SERPINE1 عبر تقنية NGS يحدد جميع الطفرات المرتبطة بأمراض التجلط بدقة متناهية.

2. Is home sample collection truly sterile and reliable for genetic testing?

Snippet Answer: Yes, our DHA-licensed phlebotomists use ISO-certified cold-chain kits, ensuring sample integrity equal to hospital collection for NGS workflows.

Blood drawn in EDTA or DNA FTA cards is immediately stabilized and transported at 2–8°C to our central laboratory. Viability is confirmed by spectrophotometry before extraction.

خدمة السحب المنزلي تتم وفق بروتوكولات نقل مبردة معقمة تماماً وتفي بمعايير الاختبارات الجينية.

3. What happens after I receive my SERPINE1 genetic report?

Snippet Answer: A post- teleconsultation with a DHA-licensed genetic counsellor explains your results, clarifies variant significance, and guides preventive strategies.

Your personalized report includes actionable recommendations, such as serial D-dimer monitoring, lifestyle modifications, or prophylactic measures, always aligned with your primary physician’s care plan.

بعد إصدار التقرير، تحصل على استشارة جينية هاتفية لفهم النتائج والخطوات الوقائية المناسبة.

This service complies with Federal Decree-Law No. 41 of 2024 on Health Data (Art. 87), UAE PDPL (Federal Decree-Law No. 45 of 2021), and CDS Law 2026 for minor genetic testing. ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139). DHA Facility License: 9834453.

ICD-10-CM (2026): Z15.89, D68.59, I82.401 | LOINC: 83019-5 | Methodology: Next-Generation Sequencing (Illumina) with Sanger confirmation.

دعم ثنائي اللغة متاح

التحقق من التغطية التأمينية

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توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.

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