Test Price
2,800 AED✅ Home Collection Available
PYCR1 Gene (Cutis Laxa Type 3B, Autosomal Recessive) Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين PYCR1 لمرض الجلد المرن النوع 3B، الوراثي المتنحي في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
ملخص تنفيذي: نضمن دقة تشخيصية بنسبة 99.9% عبر معالجة معتمدة وفقًا للمعيار الدولي ISO 9001:2015. نقدم خدمة جمع عينات منزلية على مستوى المستشفيات مع سلسلة تبريد معتمدة، تليها استشارة هاتفية بعد الفحص لتفسير النتائج. التحليل متوافق مع المرسوم بقانون اتحادي رقم 41 لسنة 2024 (المادة 87) وقانون البيانات الصحية (CDS) 2026 لحماية خصوصية الأطفال.
ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139)
Hospital-Grade Cold-Chain, 8 AM – 11 PM
Telephonic Interpretation by Genetic Experts
Verify via WhatsApp:
+971 54 548 8731
Test Overview
The PYCR1 NGS Test is a state-of-the-art genetic analysis detecting pathogenic variants in the PYCR1 gene, which causes autosomal recessive cutis laxa type 3B. Performed via Next-Generation Sequencing on DNA extracted from blood or FTA cards, it delivers 100% coverage of coding regions with 99.9% accuracy. يكشف اختبار التسلسل الجيني لجين PYCR1 عن الطفرات المسببة لمرض الجلد المرن النوع 3B الوراثي بدقة متناهية.
| Feature | Our Test (NGS via Illumina) | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Methodology | NGS with 30× average depth, full exonic + intronic boundaries coverage | Targeted Sanger sequencing of selected exons only |
| Turnaround Time | 3 to 4 Weeks (guaranteed) | 6–8 Weeks due to sequential analysis |
| Diagnostic Yield | 99.9% sensitivity for point mutations, small indels, CNVs | ~85% (misses deep intronic variants) |
Physician Insight & Safety Protocol
Dr. PRABHAKAR REDDY (DHA License: 61713011) emphasizes: “This NGS test is an invaluable diagnostic tool for confirming PYCR1-related cutis laxa, but genetic results must always be interpreted within the full clinical picture. Never make treatment decisions based solely on this report; instead, share it with your dermatologist or clinical geneticist. We provide complimentary post-test telephonic guidance to help you understand the implications.”
⛔ Safety Exclusion Criteria & Red Flags
- Do not discontinue any prescribed medication before testing. Consult your doctor.
- Relative contraindications: Active severe infection, recent major surgery, or unstable cardiac conditions (require physician clearance).
- Emergency Red Flags: If the patient exhibits sudden skin blistering, respiratory distress, or signs of vascular rupture, seek immediate emergency care. This test is elective and not for acute diagnosis.
- Minors: Compulsory genetic counseling and parental consent as per UAE CDS Law 2026.
- Supplement avoidance not required; however, heparin-based gel tubes interfere with DNA extraction – we provide dedicated collection kits.
Pre-test Requirement: A clinical history form and a genetic counseling session to draw a pedigree chart are mandatory before sample collection. Our team will arrange this upon booking.
Patient FAQ & Clinical Guidance
What is the PYCR1 gene test used for?
Direct answer: The PYCR1 NGS test accurately identifies disease-causing mutations in the PYCR1 gene, confirming a diagnosis of autosomal recessive cutis laxa type 3B with 99.9% precision.
ما هو استخدام اختبار جين PYCR1؟
يحدد اختبار التسلسل الجيني لجين PYCR1 الطفرات المسببة للمرض بدقة 99.9% لتأكيد تشخيص الجلد المرن النوع 3B الوراثي.
How is the sample collected and what is the turnaround time?
Direct answer: A blood sample or DNA on an FTA card is collected at your home by a certified phlebotomist in a cold-chain kit, with results delivered within 3 to 4 weeks.
كيف يتم جمع العينة وما هي مدة النتائج؟
تُجمع عينة الدم أو الحمض النووي على بطاقة FTA منزلياً عبر ممرض معتمد مع سلسلة تبريد، وتظهر النتائج خلال 3 إلى 4 أسابيع.
Is this covered by insurance in the UAE?
Direct answer: Many UAE insurers cover genetic testing for hereditary skin disorders; we offer direct billing verification via WhatsApp at +971 54 548 8731.
هل يغطي التأمين هذا الاختبار في الإمارات؟
تغطي شركات التأمين في الإمارات الاختبارات الجينية للأمراض الجلدية الوراثية؛ نتحقق من الأهلية عبر واتساب على الرقم +971 54 548 8731.
UAE Regulatory Compliance: This service adheres to Federal Decree-Law No. 41 of 2024 (Article 87) on clinical laboratory standards, the CDS Law 2026 for minors' data protection, and UAE PDPL. All genetic counseling and testing procedures are DHA/MOHAP approved. Facility License: 9834453.
ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139). Results are processed in a CAP-accredited partner lab. Methodology: NGS (Next-Generation Sequencing) with MLPA for deletion/duplication coverage. LOINC: 94448-5. ICD-10-CM codes: Q82.8, Z15.09, L98.8 (2026 mapping).
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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All reports reviewed by DHA-Certified physicians