Test Price
2,800 AED✅ Home Collection Available
POMC Gene Obesity, Early-Onset, Susceptibility – Genetic Test in Dubai, UAE | 2,800 AED
Executive Summary & Core Metrics
Your Genomic Advantage at a Glance
- Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO-accredited NGS processing with Sanger confirmation.
- Premium Logistics: VIP mobile phlebotomy and temperature-controlled cold-chain home collection available daily from 8 AM to 11 PM.
- Clinical Guidance: Telephonic post-test counselling by a DHA-certified genetic counsellor for result interpretation and management planning.
- Insurance Verification: Direct billing confirmation via WhatsApp at +971 54 548 8731.
Core Metrics
- Price: 2,800 AED inclusive of counselling and logistics.
- Turnaround Time: 3–4 weeks from sample receipt.
- Methodology: Full gene sequencing plus CNV detection by NGS.
- Regulatory Status: DHA-licensed and ISO 9001:2015 certified.
Test Overview & Methodology
The POMC gene (proopiomelanocortin) test screens for pathogenic variants that cause severe early-onset obesity, adrenal insufficiency, and altered pigmentation. Our service combines next-generation sequencing with expert clinical interpretation for Emirati and expatriate patients alike. The analysis covers the entire coding region and splice sites, with copy number variant detection included as standard. All positive findings are confirmed via Sanger sequencing to eliminate false positives.
| Feature | Our Test – POMC Gene UAE | Standard NGS Panel Alternative |
|---|---|---|
| Precision | 99.9% sensitivity; full gene sequencing ± CNV analysis | ~95% sensitivity; limited to known hotspots only |
| Methodology | NGS with Sanger validation for all pathogenic findings | NGS without confirmatory sequencing |
| Turnaround Time | 3–4 Weeks with ISO-certified cold-chain logistics | 4–6 Weeks via routine shipping |
| Counselling | Mandatory pre- and post-test genetic counselling included | Optional; often not included in panel price |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh (Consultant Medical Genetics, DHA: 9294403):
"A positive POMC variant can explain lifelong struggles with weight and endocrine health, but it is never a standalone diagnosis. I advise every patient to interpret these findings strictly within the context of a full metabolic and endocrine evaluation. Never adjust or stop prescribed hormone replacement therapy without specialist oversight. This test opens the door to targeted management strategies, not unnecessary alarm."
Advisory – Medication & Hormonal Therapy
⚠️ Clinical Warning: Do not discontinue any prescribed medication, especially corticosteroids or adrenal replacement therapy, without explicit guidance from your endocrinologist. Abrupt cessation can precipitate adrenal crisis.
Exclusion Criteria & Safety Red Flags
- Exclusion: Individuals under 18 years without court-appointed guardian consent as required by Federal Decree-Law No. 4 of 2016 on Medical Liability.
- Exclusion: Acute medical instability such as recent hospitalisation or active infection – postpone sample collection until resolved.
- Red Flag – Seek Emergency Care Immediately: Sudden altered consciousness, severe hypotension, or symptoms suggestive of adrenal crisis including extreme fatigue, vomiting, or dehydration. Proceed to the nearest emergency room.
- Red Flag: If a known pathogenic POMC variant is detected and you experience rapid weight gain, low blood pressure, or skin hyperpigmentation, contact your endocrinologist within 24 hours.
Patient FAQ & Clinical Guidance
1. What is the clinical utility of the POMC gene test?
This test identifies pathogenic POMC variants responsible for early-onset, severe obesity, enabling targeted endocrine and lifestyle interventions from infancy onward. A positive result guides hormone replacement therapy and helps prevent misdiagnosis of exogenous obesity. The result carries the most impact when discussed with a paediatric endocrinologist and a certified genetic counsellor.
2. How does this test differ from a standard obesity panel?
Our focused NGS analysis sequences the entire POMC gene with copy number variant detection, providing significantly higher resolution than broad obesity panels that may miss critical deep intronic mutations. This targeted approach reduces false negatives and shortens turnaround time while maintaining strong clinical relevance for classic proopiomelanocortin deficiency.
3. Is genetic counselling mandatory before and after the test?
Yes, DHA regulations and international best practice require pre-test counselling to document informed consent and family medical history, followed by post-test counselling for result interpretation. Our counsellors draw a detailed pedigree, discuss all potential outcomes, and prepare you for clinical decision-making, all in full compliance with UAE data privacy standards under Federal Decree-Law No. 45 of 2021 (PDPL).
4. What sample type is required and how is it collected?
A standard peripheral whole blood sample is collected via VIP mobile phlebotomy or at our Dubai Healthcare City laboratory. Our temperature-controlled cold-chain logistics ensure sample integrity from collection to processing. Home collection is available daily from 8 AM to 11 PM with advance booking.
UAE Regulatory & Data Privacy Adherence
Your Data and Safety Are Protected by UAE Federal Law
- Data Privacy: Fully compliant with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL). All genomic data is encrypted, access-controlled, and never shared without explicit consent.
- Health Information Governance: Adheres to Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields, ensuring secure handling of electronic health records and telehealth communications.
- Medical Liability & Patient Consent: All procedures follow Federal Decree-Law No. 4 of 2016 on Medical Liability, guaranteeing informed consent, patient rights, and safe clinical practice.
- Quality Certification: ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139) with an integrated laboratory quality management system.
Clinical & Logistical Metadata
| Test Name | POMC Gene Obesity, Early-Onset, Susceptibility – Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood – VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily 8 AM – 11 PM) |
| Methodology Used | Next-Generation Sequencing (NGS) with Sanger Validation and CNV Detection |
| ICD-10-CM Code | E66.09 |
| LOINC Code | 94233-4 |
| DHA Facility License & Laboratory Address | DHA License: 1143 | DNA Labs UAE – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians