Test Price
2,800 AED✅ Home Collection Available
PLA2G6 Gene: Infantile Neuroaxonal Dystrophy Type 1 (INAD) Genetic Test in UAE | 2,800 AED | 2026 DHA Guidelines
تحليل جين PLA2G6 – مرض الحثل العصبي المحوري الطفولي النوع 1 في الإمارات | 2,800 درهم | معتمد من هيئة الصحة بدبي
الملخص التنفيذي
فحص جيني دقيق لطفرة PLA2G6 للكشف عن الحثل العصبي المحوري الطفولي النوع الأول (INAD) مع حساسية 99.9%، وفق أعلى معايير الجودة وخصوصية البيانات الإماراتية.
- Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO 9001:2015 accredited NGS processing.
- Premium Logistics: Paid hospital‑grade home collection (8 AM–11 PM) with ISO‑certified cold‑chain transport.
- Clinical Guidance: Complimentary telephonic post‑test counselling with a DHA‑licensed neurologist.
- Insurance: Direct billing verification via WhatsApp +971 54 548 8731.
Test Overview
The PLA2G6 Genetic Test examines the entire coding region of the PLA2G6 gene to identify pathogenic variants responsible for Infantile Neuroaxonal Dystrophy Type 1 (INAD), a rare fatal neurodegenerative disorder. يكشف هذا التحليل الجيني المتقدم عن طفرات جين PLA2G6 المسببة للحثل العصبي المحوري الطفولي بدقة تشخيصية عالية.
| Feature | Our NGS Test (DNA Health Lab) | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Methodology | Next Generation Sequencing (full‑gene, all exons) | Sanger sequencing (selected amplicons only) |
| Precision | 99.9% analytical sensitivity | ~99% sensitivity, limited by target coverage |
| Turnaround | 3–4 weeks | 6–8 weeks for equivalent coverage |
| Genetic Counselling | Pre‑ and post‑test tele‑counselling included | Often requires separate referral |
Pre‑Test Requirements (MOHAP‑Compliant)
- A clinical history of the patient must be provided.
- Mandatory genetic counselling session to draw a pedigree chart of affected family members.
- Sample: 2‑5 mL whole blood (EDTA tube), extracted DNA, or one drop of blood on an FTA card.
- No special fasting or medication cessation required; continue prescribed treatments.
Physician Insight & Safety Protocol
“As a neurologist, I fully appreciate the emotional weight carried by families seeking answers for progressive neurological decline in a child. This genetic test is not merely a laboratory result – it is a compass for early supportive care, accurate prognosis, and informed family planning. Please always interpret any test finding in the context of a thorough neurological examination and, if necessary, brain MRI.”
— Dr. PRABHAKAR REDDY, DHA License 61713011, Consultant Neurologist.
Medication Warning:
Do not discontinue any prescribed medications, anti‑seizure drugs, or nutritional support without consulting your treating neurologist.
Exclusion Criteria & Emergency Red Flags:
- Active bleeding disorder or severe thrombocytopenia – inform the phlebotomist before collection.
- Patients on high‑dose anticoagulants may require specialist venous access; contact us in advance.
- If the child experiences sudden loss of consciousness, uncontrolled seizures, or respiratory distress, seek emergency medical attention immediately – do not wait for the test result.
Patient FAQ & Clinical Guidance
1. What does the PLA2G6 genetic test detect and why is it recommended?
The PLA2G6 gene test detects pathogenic mutations causing infantile neuroaxonal dystrophy type 1 (INAD), a severe neurodegenerative disorder presenting in early childhood with regression of motor and cognitive abilities. Neurologists and pediatricians order this test when clinical symptoms such as hypotonia, spasticity, vision loss, and MRI findings suggest INAD. A positive result confirms the diagnosis, guides management, and enables genetic counselling for future pregnancies.
يكشف اختبار جين PLA2G6 عن الطفرات المرضية المسببة للحثل العصبي المحوري الطفولي النوع الأول، وهو اعتلال عصبي تنكسي نادر يظهر في الطفولة المبكرة مع تراجع المهارات الحركية والإدراكية. يُطلب عند الاشتباه السريري، ويؤكد التشخيص لتوجيه التدبير العائلي والاستشارة الوراثية.
2. How accurate is the Genetic Test compared to older methods?
Our NGS‑based provides 99.9% analytical sensitivity for point mutations and small insertions/deletions across all PLA2G6‑coding exons, significantly outperforming Sanger sequencing in speed and coverage. This method is endorsed by 2026 DHA guidelines for rare diseases because it reduces false‑negative rates and identifies both known and novel variants. Results are interpreted using curated clinical databases, and each report is reviewed by a molecular geneticist.
دقة اختبار التسلسل المتقدم (NGS) تفوق 99.9% مع تغطية كاملة لمناطق الترميز، مما يجعله المعيار الذهبي لتشخيص الأمراض الوراثية النادرة وفق إرشادات هيئة الصحة بدبي لعام 2026.
3. Will my insurance cover the cost, and how can I verify?
Many UAE insurers now include rare‑disease genetic testing under inpatient or outpatient benefits, and our team verifies your coverage directly via WhatsApp before sample collection. Send your Emirates ID and insurance card to +971 54 548 8731 for a free benefits check. We are also listed with Daman, Thiqa, NextCare, and other major networks. Self‑pay options are available at 2,800 AED, with flexible installment plans upon request.
تشمل العديد من بطاقات التأمين في الإمارات تغطية الفحوصات الجينية للأمراض النادرة. يُرجى إرسال نسخة من الهوية الإماراتية وبطاقة التأمين عبر واتسآب للتحقق الفوري من التغطية.
Compliant with Federal Decree‑Law No. 41 of 2024 (Art. 87: Genetic Data Protection) and UAE PDPL. DHA‑regulated facility license: 9834453. ISO 9001:2015 certified (INT/EGQ/2509DA/3139). Last updated March 2026.
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التحقق من التغطية التأمينية
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Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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All reports reviewed by DHA-Certified physicians