Test Price
2,800 AED✅ Home Collection Available
PIGL Gene CHIME Syndrome Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل تسلسل الحمض النووي لجين PIGL لمتلازمة CHIME في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary: The PIGL gene NGS test is a definitive molecular diagnostic tool for CHIME syndrome (Coloboma, Heart defects, Ichthyosiform dermatosis, Mental retardation, Ear anomalies). Conducted via Next‑Generation Sequencing (NGS) with 99.9% diagnostic sensitivity, this test is processed through our ISO‑certified laboratory. الفحص الجيني المتقدم باستخدام تقنية التسلسل الجيني من الجيل التالي (NGS) للكشف عن الطفرات في جين PIGL المرتبط بمتلازمة CHIME. دقة تشخيصية تصل إلى 99.9%، مع سحب منزلي معتمد، وإرشاد سريري بعد الفحص.
- ✓Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing (ISO 9001:2015 Cert: INT/EGQ/2509DA/3139).
- ✓Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold‑Chain Home Collection and VIP Mobile Phlebotomy (8 AM – 11 PM).
- ✓Clinical Guidance: Telephonic Post‑Test Clinical Guidance in result interpretation by DHA‑licensed specialists.
- ✓Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Clinical Utility
The PIGL gene test analyzes the entire coding region of the PIGL gene using Next‑Generation Sequencing (NGS) to identify pathogenic variants responsible for CHIME syndrome, a rare neuroectodermal disorder. يكشف تحليل جين PIGL عن الطفرات المسببة لمتلازمة CHIME، مما يسمح بتشخيص دقيق وخطط علاجية مخصصة.
| Feature | Our Test (DNA Labs UAE) | Closest Alternative |
|---|---|---|
| Precision | Full‑gene NGS with copy number variant detection | Limited hotspot panel |
| Methodology | Illumina NGS + Sanger confirmation | Sanger sequencing only |
| Turnaround | Reliable 3–4 weeks with dedicated case manager | 6–8 weeks |
| Post‑Test Support | Included telephonic clinical guidance & genetic counselling | Report only |
Physician Insight & Safety Protocol
“A positive PIGL mutation confirms the clinical suspicion of CHIME syndrome and enables early intervention for cardiac, ophthalmologic, and developmental challenges. However, a negative result does not exclude other dysmorphology syndromes; always correlate with phenotype and family history. Genetic counselling is imperative before testing.” — Dr. PRABHAKAR REDDY (DHA License: 61713011)
Medication Warning:
Do not discontinue prescribed medication without consulting your doctor. This test does not replace ongoing medical management.
Exclusion Criteria & Emergency Red Flags:
- Active febrile illness or acute infection requiring urgent care.
- Recent blood transfusion (within 2 weeks) that may interfere with DNA extraction.
- Individuals unable to provide informed consent without a legal guardian (see UAE CDS Law 2026 for minors).
- Seek immediate emergency care if the patient experiences seizures, cyanosis, or acute cardiac symptoms unrelated to the collection process.
Frequently Asked Questions & Clinical Guidance
1. What is the PIGL gene CHIME syndrome test and who should consider it?
The PIGL gene NGS test is a next‑generation sequencing analysis that detects disease‑causing variants in the PIGL gene, confirming a diagnosis of CHIME syndrome in patients with suggestive dysmorphic features, congenital heart disease, and skin anomalies. يُستخدم هذا الفحص لتأكيد تشخيص متلازمة CHIME عند الرضع والأطفال الذين يعانون من تشوهات خلقية متعددة، وأمراض جلدية، وتأخر ذهني.
2. How is the sample collected and is home collection available in the UAE?
Our DHA‑licensed phlebotomists perform a painless blood draw at your home, office, or any preferred location across all seven emirates between 8 AM and 11 PM, using a cold‑chain transport system that preserves sample integrity until it reaches our ISO‑certified laboratory. نوفر خدمة سحب الدم المنزلي على مستوى الإمارات، مع نقل مبرد معتمد للحفاظ على العينة من نقطة الجمع وحتى المختبر.
3. What does a positive result mean and what are the next steps?
A positive report identifies a pathogenic or likely pathogenic variant in PIGL, allowing your referring pediatrician or clinical geneticist to coordinate multidisciplinary care with cardiology, dermatology, ophthalmology, and developmental specialists, and to offer cascade family testing. في حال كانت النتيجة إيجابية، يتم التواصل مع الطبيب المختص لوضع خطة علاجية متعددة التخصصات، بالإضافة إلى تقديم الاستشارة الوراثية للأسرة.
UAE Regulatory & Quality Compliance
- Laboratory operates under DHA Facility License: 9834453.
- All procedures comply with Federal Decree‑Law No. 41 of 2024 on Healthcare Data Privacy (Article 87), UAE PDPL, and the 2026 CDS Law for minors.
- ISO 9001:2015 Certified Quality Management System (Certificate: INT/EGQ/2509DA/3139).
- Pre‑ genetic counselling session is mandatory and includes pedigree charting per DHA/MOHAP standards.
- Contact for insurance and appointments: +971 54 548 8731
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Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
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All reports reviewed by DHA-Certified physicians