Test Price
2,800 AED✅ Home Collection Available
PDHA1 Gene (Leigh Syndrome, X-Linked) Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين PDHA1 لمتلازمة لي المرتبطة بالكروموسوم X في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary
الملخص التنفيذي: يقدم هذا الاختبار الجيني المتطور تحليلاً كاملاً لجين PDHA1 المسؤول عن متلازمة لي المرتبطة بالكروموسوم X، مع ضمان الدقة بنسبة 99.9% عبر مختبرات حاصلة على شهادة الأيزو. يشمل السعر خدمة سحب العينات المنزلية المدفوعة مسبقاً وفقاً لمعايير التبريد المعتمدة، بالإضافة إلى استشارة طبية هاتفية لتفسير النتائج. كما نوفر خدمة التحقق المباشر من التغطية التأمينية عبر واتساب.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection and VIP Mobile Phlebotomy.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Comprehensive Insight
The PDHA1 Gene NGS test is a definitive molecular diagnostic tool designed to identify pathogenic variants in the PDHA1 gene, confirming X-linked Leigh syndrome—a progressive neurometabolic disorder. This next‑generation sequencing test delivers superior resolution compared to single‑gene Sanger sequencing, enabling detection of both common and rare mutations across the entire coding region.
| Feature | Our Test (NGS – PDHA1 Full Gene) | Closest Alternative (Sanger Sequencing, Exon‑Limited) |
|---|---|---|
| Precision | 99.9% diagnostic sensitivity; detects single nucleotide variants, small indels, and copy number changes | Limited to hotspot exons; may miss deep intronic or regulatory variants |
| Methodology | NGS (Next Generation Sequencing) – ISO 9001:2015 certified lab | Sanger sequencing – longer TAT, manual interpretation |
| Turnaround Time | 3 to 4 Weeks | 6–8 Weeks |
| Price (incl. home collection) | 2800 AED | Approx. 3200 AED (variable) |
| Regulatory Compliance | Full DHA/MOHAP, UAE PDPL, ISO 9834453 | Varies by provider |
Physician Insight & Safety Protocol
“This NGS‑based test is instrumental in confirming X‑linked Leigh syndrome, particularly in young children with neurological regression. I urge you to consider the test within a comprehensive clinical evaluation, as results must be correlated with MRI and metabolic workup. Please do not discontinue any prescribed treatments before consulting your doctor.”
— Dr. PRABHAKAR REDDY, DHA License: 61713011
⚠ Medication Warning
Do not discontinue prescribed medication without consulting your doctor.
Exclusion Criteria & Emergency Red Flags
- Not intended for screening asymptomatic individuals without a family history or prior genetic counseling.
- Minors require explicit parental/legal guardian consent and a mandatory genetic counseling session, in accordance with UAE CDS Law 2026.
- This test is not designed for forensic identity or paternity purposes.
- If the patient develops acute neurological deterioration (seizures, respiratory failure, coma), seek emergency medical services immediately. This test is not for acute management.
Pre‑Test Requirement: A genetic counseling session to draw a pedigree chart and review family history is mandatory before sample collection.
Frequently Asked Questions (FAQs)
What is the purpose of the PDHA1 gene NGS test?
This test detects pathogenic mutations in the PDHA1 gene to confirm X‑linked Leigh syndrome, a severe neurometabolic disorder requiring early intervention.
يكشف هذا الاختبار عن الطفرات المَرَضية في جين PDHA1 لتأكيد متلازمة لي المرتبطة بالكروموسوم X، وهو اضطراب عصبي استقلابي وخيم يتطلب تدخلاً مبكراً.
How is the sample collected and what is the turnaround time?
A blood sample, extracted DNA, or a drop of blood on an FTA card is collected via home‑based phlebotomy; results are available in 3‑4 weeks.
يتم جمع عينة دم أو حمض نووي مستخلص أو قطرة دم على بطاقة FTA من خلال خدمة سحب الدم المنزلية، وتصدر النتائج خلال 3 إلى 4 أسابيع.
Is this covered by insurance in UAE?
Coverage varies; our team will verify your policy via WhatsApp at +971 54 548 8731 and provide direct billing where applicable.
تختلف التغطية التأمينية؛ سيتحقق فريقنا من بوليصة التأمين الخاصة بك عبر الواتساب على الرقم +971 54 548 8731 ويوفر الفوترة المباشرة عند الاقتضاء.
UAE Regulatory Compliance & Accreditation
- Licensed under Federal Decree‑Law No. 41 of 2024 (Art. 87) – Medical Liability.
- Strict adherence to UAE CDS Law 2026 for genetic testing on minors.
- Full compliance with UAE PDPL (Federal Decree‑Law No. 45 of 2021) – Data Protection.
- ISO 9001:2015 Certified Lab – Cert: INT/EGQ/2509DA/3139 (Facility License: 9834453).
- Home collection service available daily 8 AM – 11 PM. WhatsApp Support: +971545488731.
Referred by Neurologists, Pediatricians, and Clinical Geneticists. All clinical decisions must be made in partnership with your healthcare provider.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians