Test Price
2,800 AED✅ Home Collection Available
NCF1 Gene Chronic Granulomatous Disease, Autosomal Recessive, Cytochrome b-Positive Type 1 – Genetic Test in UAE | 2800 AED | DHA Certified
Executive Summary & Core Metrics
- ✓Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified Laboratory Processing (Cert: INT/EGQ/2509DA/3139).
- ✓Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection (Blood, Extracted DNA, or FTA Card). VIP Mobile Phlebotomy available 8 AM – 11 PM.
- ✓Clinical Guidance: Post-test telephonic interpretation with a Consultant Medical Geneticist.
- ✓Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The NCF1 gene encodes p47-phox, a critical component of the NADPH oxidase complex; pathogenic variants cause autosomal recessive chronic granulomatous disease type 1, leading to recurrent bacterial and fungal infections. This NGS-based test comprehensively analyses the entire NCF1 gene, including copy number variations and pseudogene-mediated recombination, providing definitive molecular diagnosis for affected individuals and carrier status for family members.
| Feature | Our NGS Test | Closest Alternative (Sanger) |
|---|---|---|
| Methodology | Next-Generation Sequencing (full gene + CNV analysis) | Targeted Sanger sequencing of hot-spot mutations |
| Diagnostic Sensitivity | >99.9% | ~85% (misses large deletions) |
| Turnaround Time | 3 – 4 Weeks | 6 – 8 Weeks |
| Price (AED) | 2800 | ~3500 |
| Sample Options | Blood, Extracted DNA, One drop on FTA Card | Blood only |
Physician Insight & Safety Protocols
“As a clinician, I understand the anxiety surrounding a potential diagnosis of chronic granulomatous disease for your child or family member. This advanced genetic test provides a definitive answer, but the results must always be interpreted in the context of your complete clinical picture and immunological workup. Please do not make any treatment decisions without discussing them in-depth with your specialist.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Safety Advisory
Do not discontinue prescribed medication (including prophylactic antibiotics or antifungals) without consulting your doctor.
Exclusion Criteria & Emergency Red Flags
- Exclusion: This test is not indicated for individuals without clinical suspicion of CGD; healthy carrier screening requires separate pre-test genetic counselling.
- Exclusion: Patients with active severe infection or febrile illness should postpone collection until clinically stable.
- Red Flag: If you experience high fever, deep abscess, severe respiratory distress, or signs of sepsis, seek immediate emergency care. This genetic test is not a substitute for urgent medical evaluation.
Patient FAQ & Clinical Guidance
1. What does a positive NCF1 gene test result mean for my health?
Direct answer: A positive result confirms autosomal recessive chronic granulomatous disease type 1 caused by two pathogenic variants in the NCF1 gene.
This means your NADPH oxidase function is severely impaired, predisposing you to recurrent bacterial and fungal infections. Your immunologist will correlate the result with neutrophil function tests (e.g., DHR assay) and advise a personalised prophylaxis plan. Family members may wish to consider carrier testing.
2. Is the home blood collection service safe and DHA-compliant?
Direct answer: Our DHA-licensed phlebotomists use ISO-certified cold-chain transport, ensuring sample integrity and full regulatory compliance.
All home visits are conducted by trained, DHA-registered professionals carrying valid identification. The collection kit preserves DNA on FTA cards or vacutainers at 2–8°C until arrival at our ISO 9001:2015 lab. This process adheres to UAE Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 concerning the Use of Information and Communication Technology in Health Fields.
3. How long will it take to receive my results, and will I get genetic counseling?
Direct answer: Results are delivered within 3 to 4 weeks, with a complimentary post-test telephonic genetic counseling session.
Your secure PDF report will be shared via our encrypted patient portal. Once the report is available, our genetic counsellor will schedule a 30-minute call (English or Arabic) to explain the findings, implications for family members, and next steps. All genetic data is stored in compliance with UAE health data sovereignty laws.
UAE Regulatory & Data Privacy Adherence
This genetic testing service operates under the regulatory oversight of the Dubai Health Authority (DHA) and complies with all applicable UAE federal laws. Patient data is handled in accordance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability. All laboratory procedures are ISO 9001:2015 certified, ensuring the highest standards of quality and confidentiality.
Clinical & Logistical Metadata
| Test Name | NCF1 Gene Chronic Granulomatous Disease, Autosomal Recessive, Cytochrome b-Positive Type 1 – Genetic Test |
| Price (AED) | 2,800 |
| Turnaround Time | 3 – 4 Weeks |
| Sample Type / Matrix | Peripheral Blood, Extracted DNA, or FTA Card (VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection Available Daily 8 AM – 11 PM) |
| Methodology Used | Next-Generation Sequencing (full gene + CNV analysis) |
| ICD-10-CM Code | D71 (Chronic granulomatous disease) |
| LOINC Code | 94453-4 (NCF1 gene mutation analysis) |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians