Test Price
2,800 AED✅ Home Collection Available
MPDU1 Gene Glycosylation Disorder Type 1F Genetic Test
Executive Summary & Core Metrics
- 99.9% Diagnostic Sensitivity – Next‑generation sequencing performed in an ISO 9001:2015 accredited laboratory.
- VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection – Available daily from 8 AM to 11 PM across all UAE emirates.
- Post‑Test Genetic Consultation – Telephonic review of results with a board‑certified medical geneticist.
- Insurance Support – Direct billing verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
This next‑generation sequencing (NGS) assay interrogates the entire MPDU1 gene, including all coding exons and flanking intronic regions, to detect pathogenic variants associated with congenital disorder of glycosylation type If (CDG‑If). The test achieves comprehensive coverage for single‑nucleotide variants, small insertions/deletions, and copy‑number variations, providing the definitive molecular diagnosis needed for early metabolic management, genetic counselling, and family risk assessment.
| Feature | Our Test (NGS – Gold Standard) | Closest Alternative (Sanger Panel) |
|---|---|---|
| Method | Next Generation Sequencing (full gene ± CNV detection) | Sanger sequencing of selected hotspots |
| Gene Coverage | 100% coding regions + exon‑intron boundaries | Only predefined mutation sites (approx. 20–40% of known variants) |
| Turnaround | 3 – 4 Weeks | 2 – 3 Weeks |
| Clinical Sensitivity | >99% for SNVs & indels; copy‑number variants included | ~80% (only known recurrent mutations) |
| Price | 2800 AED | 1500 – 2000 AED (limited utility) |
Physician Insight & Safety Protocols
“As a consultant in medical genetics, I emphasise that MPDU1 sequencing should be obtained after thorough pretest counselling and construction of a three‑generation pedigree. The interpretation of NGS results must always be correlated with clinical and biochemical data. Variants of uncertain significance may arise; do not alter or discontinue any prescribed therapy without full medical correlation.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory & Safety Precautions
Medication and Treatment Caution
Do not stop, start, or modify any medication or therapeutic regimen without explicit guidance from the referring physician. Genetic test results may take several weeks; ongoing medical care should continue unchanged during this period. If you experience new or worsening symptoms (e.g., seizures, feeding difficulties, or altered consciousness), seek immediate emergency care.
Exclusion Criteria & Emergency Red Flags
- Acute febrile illness or severe anaemia (haemoglobin <7 g/dL) at the time of blood draw.
- Inability to provide valid informed consent; for minors, a legal guardian must consent.
- Patient currently in metabolic crisis requiring immediate stabilisation – postpone elective genetic testing.
- Urgent signs – new‑onset seizures, progressive encephalopathy, or severe vomiting – proceed to the nearest emergency department.
UAE Federal Decree‑Law No. 4 of 2016 on Medical Liability governs consent and safety in diagnostic procedures.
Patient FAQ & Clinical Guidance
1. Why is the MPDU1 gene test recommended for suspected congenital disorder of glycosylation?
The MPDU1 gene test is the gold standard for molecular confirmation of CDG type If. It enables targeted multidisciplinary management, accurate recurrence risk counselling, and early intervention that can significantly improve outcomes.
2. What sample is required and how is the test performed?
A standard peripheral blood sample (whole blood in EDTA tube) is required. DNA is extracted and analysed by next‑generation sequencing. VIP mobile phlebotomy with temperature‑controlled cold‑chain home collection is available daily from 8 AM to 11 PM across Dubai and all UAE emirates.
3. How long does it take to get MPDU1 gene sequencing results?
Turnaround time is 3 to 4 weeks from sample receipt. This includes comprehensive bioinformatic analysis, variant classification, and generation of a detailed clinical report suitable for the managing physician.
4. Will my health insurance cover the cost of this test?
We assist with direct billing verification. Please send a clear photo of your insurance card via WhatsApp at +971 54 548 8731, and our team will confirm coverage prior to sample collection.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE operates under DHA Facility License Number 1143 and complies with all applicable UAE federal laws. Patient data is handled in strict accordance with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Genetic information is considered highly sensitive and is stored with encryption, accessed only by authorised clinical personnel, and never shared without explicit patient consent as required by law.
Clinical & Logistical Metadata
| Test Name | MPDU1 Gene Glycosylation Disorder Type 1F Genetic Test |
| Price (AED) | 2800 AED |
| Turnaround Time | 3 – 4 Weeks |
| Sample Type / Matrix | Whole blood (EDTA) or buccal swab; VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection available daily 8 AM – 11 PM |
| Methodology Used | Next‑Generation Sequencing (full gene + CNV detection) |
| ICD-10-CM Code | E77.8 (Other disorders of glycoprotein metabolism) |
| LOINC Code | 95407-5 (MPDU1 gene sequencing) |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians