Test Price
2,800 AED✅ Home Collection Available
LAMC3 Gene Cortical Malformations, Occipital Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين LAMC3 لتشوهات القشرة الدماغية القذالية في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
- ✔99.9% Diagnostic Sensitivity – ISO 9001:2015 Certified & CAP‑aligned NGS workflow.
- ✔Premium Home Collection – Hospital‑grade cold‑chain logistics with VIP Mobile Phlebotomy (8 AM‑11 PM).
- ✔Post‑Test Clinical Guidance – Complimentary telephonic interpretation with a DHA‑licensed genetic counsellor.
- ✔Insurance Direct Billing – Verification via WhatsApp +971 54 548 8731
ملخص تنفيذي
يضمن اختبار تسلسل الجيل التالي لجين LAMC3 أعلى دقة تشخيصية وفقًا لمعايير هيئة الصحة بدبي. يتم جمع العينة منزليًا عبر فريق تمريض متنقل مع سلسلة تبريد متطورة، وتقديم استشارة هاتفية بعد النتيجة لتفسير التقرير سريريًا.
Clinical Overview & Diagnostic Advantage
The LAMC3 gene test employs next‑generation sequencing to detect pathogenic variants causing occipital cortical malformations, a severe neurodevelopmental disorder often presenting with intractable epilepsy and intellectual disability. Early molecular confirmation empowers targeted clinical management and family planning.
يكتشف اختبار جين LAMC3 الطفرات الممرضة المسببة لتشوهات القشرة الدماغية القذالية باستخدام تقنية التسلسل المتقدم، مما يتيح التشخيص المبكر ووضع خطة علاجية دقيقة.
| Feature | Our Test (NGS) | Alternative (Sanger) |
|---|---|---|
| Resolution | Full gene + CNV | Single exon |
| Sensitivity | 99.9% SNV | ~95% |
| Turnaround Time | 3–4 Weeks | 6–8 Weeks |
| Sample | Blood/FTA Card | Blood only |
Physician Insight & Safety Protocol
“As a pediatric geneticist, I see families searching for answers when their child faces developmental challenges. The LAMC3 test gives us a molecular foothold, but every result must be interpreted alongside brain MRI and clinical history. You are never alone in this journey – we will correlate findings and guide the next steps together.”
— Dr. PRABHAKAR REDDY, Consultant Pediatric Geneticist, DHA License 61713011
⚠️ Critical Medication Notice:
Do not discontinue any prescribed antiepileptic or other medication without explicit instruction from your treating physician. Altering therapy prematurely may provoke seizure exacerbation.
🚨Patient Safety & Exclusion Criteria
- Exclusion: Active febrile illness, recent blood transfusion (<2 weeks), or chemotherapy‑induced pancytopenia.
- ER Red Flags (stop collection, seek emergency care): Sudden loss of consciousness, prolonged seizure (>5 min), severe headache with vomiting.
- Genetic counselling is mandatory prior to sample submission; a detailed family pedigree must be provided.
Frequently Asked Questions
What is the LAMC3 gene and how do mutations cause cortical malformations?
Mutations in the LAMC3 gene disrupt radial glial fiber architecture, impairing neuronal migration to the occipital cortex, which results in laminar disorganization and cortical dysplasia. This leads to structural brain anomalies typically visible on MRI and often manifests as infantile spasms or refractory focal seizures. The test sequences all coding exons, detecting single nucleotide variants, small indels, and large deletions/duplications that have been associated with autosomal recessive occipital polymicrogyria and related malformations.
تؤدي الطفرات في جين LAMC3 إلى خلل في هجرة الخلايا العصبية نحو القشرة القذالية، مما يسبب تشوهات قشرية ونوبات صرعية مبكرة. يغطي الاختبار جميع الإكسونات للكشف عن الطفرات النقطية وإعادة الترتيب الكبيرة.
How is the sample collected in the UAE and what is the turnaround time?
A certified phlebotomist visits your home between 8 AM and 11 PM to draw a small blood sample, or you may submit extracted DNA on an FTA card, ensuring cold‑chain integrity until laboratory processing. The sample is transported under ISO‑validated temperature control to our DHA‑licensed facility, with results reported in 3 to 4 weeks. You will receive an SMS notification when the report is ready for download via our secure portal.
يتم أخذ العينة منزليًا عبر ممرض مرخص خلال الفترة 8 صباحًا حتى 11 مساءً، مع خيار استخدام بطاقة FTA، وتصدر النتيجة خلال 3 إلى 4 أسابيع عبر تقرير إلكتروني آمن.
Is the LAMC3 NGS test covered by insurance in Dubai and Abu Dhabi?
Most major UAE insurers, including Daman, AXA, and NAS, provide coverage for medically indicated genetic testing under genomic medicine riders, subject to pre‑authorization. Our billing team verifies your policy and obtains approval before the; direct billing is available for most networks. For an immediate eligibility check, send your insurance card copy via WhatsApp to +971 54 548 8731.
تغطي معظم شركات التأمين في الإمارات مثل ضمان وأكسا الاختبار الجيني عند وجود سبب طبي، بعد الحصول على موافقة مسبقة. يمكنك مراسلتنا على واتساب للتحقق الفوري من التغطية.
Strictly compliant with Federal Decree‑Law No. 41 of 2024 (Art. 87), UAE CDS Law 2026 relating to minors, and UAE Personal Data Protection Law (PDPL).
Facility License: 9834453 | ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139) | DHA-regulated genetic testing.
Medical disclaimer: This content is for informational purposes only and does not replace professional medical advice. Always consult a qualified healthcare provider.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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All reports reviewed by DHA-Certified physicians