Test Price
2,800 AED✅ Home Collection Available
KRT14 Gene Naegeli-Franceschetti-Jadassohn Syndrome Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل طفرة جين KRT14 لمتلازمة نيغلي-فرانشيسكيتي-ياداسون في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited NGS Processing on Illumina platforms. Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection and VIP Mobile Phlebotomy across all Emirates. Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation by a DHA-licensed genetic counsellor. Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
الملخص التنفيذي: يقدم هذا التحليل الجيني المتطور تسلسل الجيل التالي لجين KRT14 لتشخيص متلازمة نيغلي-فرانشيسكيتي-ياداسون بدقة تصل إلى 99.9% وخدمات منزلية معتمدة في الإمارات. يشمل الخدمة سحب عينات الدم منزلياً عبر فريق تمريض معتمد، واستشارة جينية قبل وبعد التحليل مع دعم مباشر للفوترة التأمينية.
Test Overview
This advanced NGS-based test sequences the entire KRT14 gene to detect point mutations, small insertions/deletions, and copy number variants causing Naegeli-Franceschetti-Jadassohn syndrome (NFJS), a rare ectodermal dysplasia with reticulate pigmentation. The test delivers clinically actionable results within 3–4 weeks, enabling precise dermatologic and genetic counselling decisions.
| Feature | Our KRT14 NGS Test | Closest Alternative (Multi-Gene Panel) |
|---|---|---|
| Precision | Single-gene deep coverage (>100x); CNV detection included | Panel may have lower coverage for KRT14; often misses exon-level CNVs |
| Method | Illumina NGS with Sanger confirmation | NGS panel without confirmatory sequencing |
| Turnaround | 3–4 Weeks | 4–6 Weeks (often batched) |
| Interpretation | Dedicated dermatogeneticist report | General genetics report |
| Price (AED) | 2800 | 3,200 – 4,500 |
Physician Insight & Safety Protocol
“As a DHA-licensed dermatologist, I emphasize that a positive KRT14 mutation confirms NFJS subtype and guides management of palmoplantar keratoderma, dental anomalies, and sweating impairment. This test must be correlated with clinical findings and a comprehensive family pedigree. Do not interpret results in isolation; post-test genetic counselling is essential to explain penetrance and reproductive options.”
— Dr. PRABHAKAR REDDY, DHA License: 61713011
⚠ Medication Warning
Do not discontinue prescribed medication without consulting your doctor. This genetic test does not replace ongoing dermatologic or systemic therapy.
Patient Safety: Exclusion Criteria & Emergency Red Flags
- Active febrile illness or infection requiring systemic antibiotics – reschedule collection post recovery.
- Severe anaemia (Hb < 8 g/dL) or current anticoagulation therapy without physician clearance.
- Emergency Red Flags: If you experience sudden blistering, widespread skin sloughing, or signs of heat intolerance (hyperthermia) before testing, seek ER care immediately—do not wait for a scheduled collection.
Patient FAQ & Clinical Guidance
1. How accurate is the KRT14 gene test for Naegeli-Franceschetti-Jadassohn syndrome diagnosis?
The NGS test achieves analytical sensitivity over 99.9% for single nucleotide variants and small indels within the KRT14 coding region, with clinical confirmation via pedigree analysis and dermatological examination.
٢. هل يشترط الصيام قبل سحب العينة لفحص جين KRT14؟
لا يشترط الصيام لفحص الحمض النووي، يمكن جمع عينة الدم أو البطاقة الورقية في أي وقت مع الالتزام بتقديم التاريخ السريري الكامل.
3. Will my insurance cover the cost of this genetic in the UAE?
Many UAE insurers cover single-gene tests for clinically indicated ectodermal dysplasias; we offer direct billing verification via WhatsApp (+971545488731) before collection, and provide the necessary DHA-compliant pre-authorisation support.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians