Test Price
2,800 AEDโ Home Collection Available
KIF1A Gene (HSN2C) Genetic Test in UAE | 2,800 AED | DHA Licensed
Executive Summary & Core Metrics
Executive Summary
The KIF1A Gene (HSN2C) Next-Generation Sequencing test delivers definitive molecular diagnosis for hereditary sensory neuropathy type 2C and related neurological disorders, enabling targeted clinical management, genetic counselling, and informed family planning. Performed under DHA regulatory oversight at DNA Labs UAE, the assay achieves 99.9% diagnostic sensitivity through ISO 9001:2015 certified processing.
- โAccuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified Processing.
- โPremium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (8 AM โ 11 PM Daily).
- โClinical Guidance: Telephonic Post-Test Clinical Correlation Session with a Consultant Medical Geneticist.
- โInsurance: Direct Billing Verification โ WhatsApp +971 54 548 8731.
Test Overview & Methodology
The KIF1A gene encodes kinesin family member 1A, a motor protein critical for neuronal cargo transport. Pathogenic variants in KIF1A cause a spectrum of autosomal dominant and recessive neurological disorders including hereditary sensory neuropathy type 2C (HSN2C), hereditary spastic paraplegia, and early-onset neurodegenerative conditions. This targeted NGS assay interrogates the full coding region plus ยฑ50 base-pair intronic flanks with deep coverage of โฅ100ร, ensuring >99.9% analytical sensitivity for single nucleotide variants and small insertions or deletions.
All testing is conducted at DNA Labs UAE, a DHA-licensed facility (License No. 1143) located in Dubai Healthcare City. Pre-test genetic counselling and pedigree charting are mandatory components of the service, fully compliant with UAE federal regulations governing medical liability and patient consent.
| Feature | Our KIF1A NGS Test | Closest Alternative (Multi-Gene Panel / WES) |
|---|---|---|
| Target Resolution | Full coding region ยฑ 50 bp intronic flanks; deep coverage โฅ 100x | Variable coverage; may miss deep intronic or regulatory variants |
| Analytical Sensitivity | >99.9% for single nucleotide variants & indels | ~95โ98% depending on capture design |
| Turnaround Time | 3โ4 Weeks | 4โ8 Weeks (WES) / 2โ4 Weeks (Panel) |
| Pre-test Genetic Counselling | Mandatory UAE-compliant genetic counselling & pedigree charting | Often optional or not included |
| UAE Regulatory Alignment | Full DHA/MOHAP & PDPL adherence | Variable |
Physician Insight & Safety Protocols
โGenetic testing for KIF1A-associated disorders provides a molecular key to unlock precise diagnosis and guide long-term neurological care. As a medical geneticist, I emphasize that every result must be interpreted within the full clinical contextโfamily history, neurological examination, and longitudinal progression. This test is a powerful tool, not a standalone verdict. Our team is committed to walking with you through every step of interpretation and decision-making.โ
โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory Notice โ Medication and Clinical Management
This genetic test result must not be used as the sole basis for discontinuing, adjusting, or initiating any prescribed neurological therapy. A face-to-face consultation with the treating physician is required before any change to medication or clinical management. The molecular finding is one component of a comprehensive diagnostic assessment.
Exclusion Criteria โ Test May Be Refused
- Sample without documented clinical history or genetic counselling note (per Federal Decree-Law No. 4 of 2016 on Medical Liability).
- Minors lacking formal guardian consent as required by UAE federal regulations.
- Specimens not collected or transported using DHA-approved cold-chain logistics.
- Self-collection without prior instruction and video verification (when applicable).
Patient FAQ & Clinical Guidance
1. What is the KIF1A gene test, and who should consider it?
The KIF1A gene test is a DNA sequencing assay that identifies disease-causing mutations in the KIF1A gene, aiding diagnosis of hereditary sensory neuropathy type 2C, hereditary spastic paraplegia, and other KIF1A-related neurological disorders. Individuals with early-onset gait disturbance, progressive spasticity, unexplained sensory loss, or a family history of undiagnosed neurological decline should consider this test. Clinical genetic counselling is mandatory before sampling.
2. How is the sample collected for the KIF1A genetic test?
The test accepts whole blood (peripheral venipuncture), extracted DNA, or dried blood spot on FTA card. Our VIP Mobile Phlebotomy service can collect samples at your home between 8 AM and 11 PM daily using temperature-controlled cold-chain packaging. A pre-collection genetic counselling session is required to document medical history and construct a three-generation pedigree.
3. How long does it take to receive results, and will a doctor explain them?
Standard reporting time is 3 to 4 weeks from sample accession. Every report includes a telephonic post-test guidance session with a consultant medical geneticist who will translate the findings into your clinical context, outline recurrence risks, and suggest next steps. This service is included in the 2,800 AED fee.
4. What is the cost of the KIF1A gene test in the UAE?
The total fee for the KIF1A Gene (HSN2C) Next-Generation Sequencing test is 2,800 AED. This includes the genetic analysis, mandatory pre-test genetic counselling, a comprehensive written report, and a post-test telephonic consultation with a consultant medical geneticist. Home collection by VIP Mobile Phlebotomy is available at no additional charge within designated service areas.
5. Is genetic counselling mandatory before this test?
Yes. UAE federal regulations require documented pre-test genetic counselling and informed consent for all hereditary genetic tests. Our genetic counsellor will guide you through the implications of possible results, discuss inheritance patterns, and obtain written consent before sample collection. This process ensures you make an informed decision aligned with your values and family context.
UAE Regulatory & Data Privacy Adherence
- Licensed by the Dubai Health Authority (DHA) under Facility License No. 1143.
- All genetic data processing complies with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL). Genomic data is never shared without explicit written consent.
- Clinical safety and patient consent protocols adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability.
- Health information handling conforms to Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
- ISO 9001:2015 Certified Quality Management System (Cert: INT/EGQ/2509DA/3139).
- Laboratory address: Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE.
Clinical & Logistical Metadata
| Test Name | KIF1A Gene (HSN2C) Genetic Test (Next-Generation Sequencing) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3โ4 Weeks |
| Sample Type / Matrix | Whole Blood, Extracted DNA, Dried Blood Spot (FTA Card) |
| Methodology Used | Next-Generation Sequencing (NGS) |
| ICD-10-CM Code | G60.8 |
| LOINC Code | 94086-1 |
| DHA Facility License & Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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