Test Price
2,800 AED✅ Home Collection Available
KDM5C Gene Sequencing (Claes-Jensen Syndrome) DNA Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
- Clinical Accuracy: 99.9% Diagnostic Sensitivity via ISO-Accredited NGS with Sanger Confirmation.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Post-Test Guidance: Telephonic Clinical Correlation & Genetic Counselling by DHA-Licensed Specialists.
- Insurance Support: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The KDM5C Gene Sequencing test definitively diagnoses X-linked syndromic intellectual disability (Claes-Jensen syndrome) using high-resolution Next-Generation Sequencing, providing molecular confirmation that guides lifelong clinical management. Our DHA-licensed laboratory employs targeted NGS with Sanger confirmation to detect pathogenic variants in the KDM5C gene, ensuring greater than 99.5% coverage of coding regions.
| Feature | Our Test – KDM5C Gene Sequencing | Closest Alternative – Whole Exome Sequencing |
|---|---|---|
| Diagnostic Precision | Targeted, full-gene NGS with high depth >99.5% coverage | Broad, may miss deep intronic variants |
| Methodology | NGS + Sanger confirmation of pathogenic alleles | NGS only; incidental findings possible |
| Turnaround Time | 3–4 Weeks | 4–6 Weeks |
| Cost | 2800 AED | ≥3500 AED |
Physician Insight & Safety Protocols
“As a Consultant Medical Geneticist, I regard the KDM5C gene sequencing test as an essential tool for resolving the diagnostic odyssey in X-linked intellectual disability. A positive result confirms the Claes-Jensen phenotype and informs personalized developmental interventions and family planning. Importantly, a negative result does not rule out other genetic causes, so comprehensive clinical phenotyping and genetic counselling remain indispensable adjuncts.” – Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403.
Medication Advisory
Medication Advisory
Do not discontinue any prescribed medication without consulting your doctor. This test is a diagnostic tool and does not replace medical management.
Exclusion Criteria & Emergency Red Flags
Exclusion Criteria & Emergency Red Flags
- Not for acute neurologic crisis; the test result arrives in weeks and is not a substitute for emergency diagnosis.
- Valid informed consent is mandatory; for minors, guardians must sign and attend pre-test genetic counselling.
- Patients with sudden loss of skills, uncontrollable seizures, or altered consciousness must proceed to the nearest emergency department immediately.
Patient FAQ & Clinical Guidance
1. What is the KDM5C Gene Sequencing test and why is it performed?
This test analyses the complete coding sequence of the KDM5C gene for pathogenic variants causing X-linked intellectual disability (Claes-Jensen syndrome) to provide a definitive molecular diagnosis. It is recommended for children and adults with developmental delay, dysmorphic features, and a family history suggestive of X-linked inheritance. Early diagnosis enables targeted developmental support, surveillance for associated anomalies, and informed family planning.
2. How is the sample collected and what is the turnaround time?
Sample collection is performed via a simple blood draw or a painless FTA card finger-prick at your home by ISO-certified phlebotomists, and results are available in 3–4 weeks. Our VIP mobile service operates from 8 AM to 11 PM, 7 days a week, ensuring minimal disruption. The sample is transported in validated cold-chain containers to our Dubai laboratory for sequencing.
3. Is this test covered by UAE health insurance and how can I claim?
Most major UAE insurers cover the KDM5C when a neurologist or clinical geneticist provides a referral, and we offer direct billing verification via WhatsApp at +971 54 548 8731. Contact us with your Emirates ID and insurance card; our team will confirm eligibility within one business day. If self-pay, you receive a detailed invoice for potential reimbursement.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance
DNA Labs UAE operates under DHA Facility License No. 1143 and complies strictly with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All clinical testing and patient consent procedures adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability, ensuring the highest standards of safety and confidentiality.
Clinical & Logistical Metadata
| Test Name | KDM5C Gene Sequencing (Claes-Jensen Syndrome) DNA Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Peripheral whole blood (EDTA) or FTA card finger-prick |
| Methodology Used | Next-Generation Sequencing (NGS) with Sanger confirmation |
| ICD-10-CM Code | Q87.8 (Other specified congenital malformation syndromes) |
| LOINC Code | 83934-6 (KDM5C gene sequencing) |
| DHA Facility License & Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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