Test Price
2,800 AED✅ Home Collection Available
HSD3B7 Gene (Bile Acid Synthesis Defect Type 1, Congenital) Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين HSD3B7 لتشخيص عيب تصنيع الحمض الصفراوي الخلقي من النوع الأول (اختبار الحمض النووي الجيني NGS) في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 15189 & ISO 9001:2015 Accredited Processing.
Premium Logistics: Hospital-Grade Home Collection (8 AM–11 PM) via ISO-Certified Cold-Chain Transport & VIP Mobile Phlebotomy.
Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation by DHA-Licensed Experts.
Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Clinical Overview
This DNA test uses Next‑Generation Sequencing (NGS) to examine the full coding region of the HSD3B7 gene. It definitively diagnoses congenital bile acid synthesis defect type 1 (BASD1), a rare metabolic hepatopathy. يُعد هذا الاختبار الجيني أداة تشخيصية قاطعة لعيب تصنيع الحمض الصفراوي الخلقي من النوع الأول، مما يُمكّن من التدخل العلاجي المبكر ويُجنّب المضاعفات الكبدية.
| Parameter | Our Test (HSD3B7 NGS) | Closest Alternative |
|---|---|---|
| Diagnostic Precision | Full gene sequencing + deletion/duplication analysis | Limited panel may miss rare variants |
| Methodology | NGS (Next‑Generation Sequencing) with bioinformatic confirmation | Sanger sequencing for selected exons only |
| Turnaround Time | 3–4 Weeks | 4–6 Weeks |
| Cost | 2800 AED | Variable, often higher with separate counseling fees |
| Regulatory Status | DHA‑Licensed Facility (9834453), ISO 9001:2015 | May lack UAE‑specific accreditation |
Physician Insight & Safety Protocol
Dr. PRABHAKAR REDDY (DHA License: 61713011): “This test should always be interpreted alongside biochemical markers and hepatic imaging. A negative result does not exclude the diagnosis if clinical suspicion remains high; a positive result guides life‑saving early bile acid replacement. Close collaboration with a metabolic geneticist is essential for optimal patient outcomes.”
⚠ Medication Warning: Do not discontinue any prescribed medication or supplement without direct consultation with your treating physician. This genetic test is not a substitute for ongoing clinical care.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Active febrile illness or suspected sepsis at the time of blood draw (may affect DNA extraction quality).
- Exclusion: Known history of severe dermatological conditions over venipuncture sites (consider buccal swab or FTA card alternative).
- Red Flag: If the patient develops rapidly worsening jaundice, encephalopathy, or coagulopathy, proceed immediately to the ER and inform the hepatology team.
- Red Flag: Syncope or anaphylactoid reaction during/after sample collection warrants urgent cessation and emergency medical support.
Patient FAQ & Clinical Guidance
Q: What is the HSD3B7 gene test and who needs it?
Key Insight: This NGS test analyses the HSD3B7 gene to diagnose congenital bile acid synthesis defect type 1 with 99.9% accuracy. It is recommended for infants with unexplained cholestasis, siblings of affected individuals, and adults with late‑onset atypical liver disease where a metabolic etiology is suspected. The utilizes DNA from blood, FTA cards, or extracted DNA and includes detailed genetic counseling.
الخلاصة السريرية: يقوم هذا الاختبار بتحليل جين HSD3B7 لتشخيص عيب تصنيع الحمض الصفراوي الخلقي بدقة تصل إلى 99.9%. يُوصى به للرضع المصابين بالركود الصفراوي غير المبرر ولأفراد العائلة المعرضين للخطر.
Q: How is the sample collected and is home service available?
Key Insight: A simple blood draw, DNA extraction, or one drop blood on FTA card is collected via our VIP home service. We offer hospital‑grade home collection across the UAE from 8 AM to 11 PM, with cold‑chain transport ensuring sample viability. The procedure is minimally invasive; for neonates, a heel‑prick or FTA card method is available upon request.
الخلاصة السريرية: يمكن جمع العينة من خلال سحب دم بسيط أو بطاقة FTA في المنزل عبر خدمة التمريض المتنقل، مع نقل مبرد وفق معايير الجودة العالمية.
Q: What is the turnaround time, cost, and insurance process?
Key Insight: Results are delivered within 3 to 4 weeks at a total cost of 2800 AED, including genetic counseling. Direct insurance billing can be verified instantly via WhatsApp; we accept most UAE medical insurance plans. The report includes a clinical interpretation and actionable recommendations, with an option for a telephonic discussion with our DHA‑licensed geneticist.
الخلاصة السريرية: تظهر النتائج خلال 3 إلى 4 أسابيع بتكلفة 2800 درهم تشمل الاستشارة الوراثية. يمكن التحقق من تغطية التأمين مباشرة عبر واتساب.
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توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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All reports reviewed by DHA-Certified physicians