Test Price
2,800 AED✅ Home Collection Available
HSD3B2 Gene 3‑Beta‑Hydroxysteroid Dehydrogenase Deficiency Type 2 Genetic Test in UAE | 2,800 AED
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO‑Accredited Processing (ISO 9001:2015 Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection (8 AM‑11 PM, daily).
- Clinical Guidance: Telephonic Post‑Test Clinical Guidance in result interpretation by a DHA‑licensed clinical geneticist.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
- Price: 2,800 AED (Complete NGS Analysis, Single Gene).
- Turnaround: Results in 3–4 weeks (21–28 business days).
Test Overview & Methodology
The HSD3B2 gene test detects pathogenic variants causing 3‑beta‑hydroxysteroid dehydrogenase deficiency type 2, a rare congenital adrenal hyperplasia that disrupts cortisol, aldosterone, and sex steroid synthesis. Our NGS‑based analysis delivers full gene coverage, enabling precise carrier detection, prenatal counseling, and early clinical intervention.
| Feature | Our Test (NGS) | Closest Alternative |
|---|---|---|
| Methodology | Next‑Generation Sequencing (NGS) of entire HSD3B2 gene | Sanger sequencing (limited to known hotspots) or biochemical steroid assay |
| Precision | 99.9% diagnostic sensitivity, detects novel mutations | 90–95% sensitivity; may miss rare/private mutations |
| Turnaround | 3–4 Weeks | 2–3 Weeks (Sanger) / 1 Week (biochemical) |
NGS replaces stepwise traditional testing; comprehensive results confirm diagnosis in a single analysis.
Physician Insight & Safety Protocols
“As a medical geneticist, I understand the profound impact of a genetic diagnosis. This single‑gene test for HSD3B2 deficiency provides definitive answers for families facing ambiguous genitalia or salt‑wasting crises, enabling precise hormone replacement and informed reproductive planning.” — Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Advisory
Do not discontinue prescribed corticosteroid or mineralocorticoid medications without direct consultation with your managing physician. Abrupt cessation may precipitate life‑threatening adrenal crisis.
Exclusion Criteria & Red Flags
- Exclusion: Individuals who have received a blood transfusion within the last 14 days; inability to provide informed consent (minors require legal guardian consent per Federal Decree‑Law No. 4 of 2016 on Medical Liability).
- Red Flags (Seek Emergency Care): Sudden vomiting, severe dehydration, hypotension, hypoglycemia, or loss of consciousness – do not delay care for laboratory testing.
Patient FAQ & Clinical Guidance
1. What is the HSD3B2 gene test used for?
The HSD3B2 gene test diagnoses 3‑beta‑hydroxysteroid dehydrogenase deficiency type 2, a rare genetic cause of congenital adrenal hyperplasia that affects cortisol and aldosterone production, leading to salt‑wasting or ambiguous genitalia in newborns. It is essential for confirming the clinical diagnosis, guiding hormone replacement, and offering carrier testing for families.
2. How is the test performed and what does it require?
A simple blood sample (venipuncture), extracted DNA, or a drop of blood on an FTA card is collected via our VIP home service; the DNA undergoes next‑generation sequencing to identify pathogenic variants in the entire HSD3B2 gene. A genetic counseling session and a family pedigree chart are mandatory before testing, as required by DHA pre‑test protocol.
3. How long will results take and who will explain them?
Results are delivered within 3 to 4 weeks, accompanied by a detailed molecular report and a scheduled telephonic consultation with a clinical geneticist or endocrinologist. This post‑test guidance ensures that you and your physician understand the findings and the recommended management plan.
UAE Regulatory & Data Privacy Adherence
Your data is protected under UAE law. All genetic and health information collected during this test is handled in strict compliance with:
- Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) – governing the collection, processing, and storage of personal data.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – ensuring secure electronic health records and telehealth practices.
- Federal Decree‑Law No. 4 of 2016 on Medical Liability – upholding patient consent and clinical safety standards.
DNA Labs UAE maintains ISO 9001:2015 certification (INT/EGQ/2509DA/3139) and adheres to DHA‑mandated privacy protocols for all diagnostic services.
Clinical & Logistical Metadata
| Test Name | HSD3B2 Gene 3‑Beta‑Hydroxysteroid Dehydrogenase Deficiency Type 2 Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 to 4 weeks (21–28 business days) |
| Sample Type / Matrix | Peripheral Whole Blood (Venipuncture), Extracted DNA, or FTA Card |
| Methodology Used | Next‑Generation Sequencing (NGS) of the entire HSD3B2 gene |
| ICD‑10‑CM Code | E25.0 (Congenital adrenal hyperplasia due to 3‑beta‑hydroxysteroid dehydrogenase deficiency) |
| LOINC Code | 81216‑7 (HSD3B2 gene full sequencing) |
| DHA Facility License & Laboratory Address | License No. 1143 Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE DNA Labs UAE |
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