Test Price
2,800 AED✅ Home Collection Available
DHA-CERTIFIED GENOMIC TEST · ISO 9001:2015 · UAE TRUSTED
FOXC2 Gene Lymphedema-Distichiasis Syndrome Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين FOXC2 لمتلازمة الوذمة اللمفية والرموش المزدوجة في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary
ملخص تنفيذي: يقدم هذا التحليل الجيني الشامل لجين FOXC2 باستخدام الجيل التالي من التسلسل (NGS) كشفاً دقيقاً لمتلازمة الوذمة اللمفية والرموش المزدوجة. يشمل ضمان الدقة بنسبة 99.9%، وخدمة سحب دم منزلي فاخرة بتقنية السلسلة الباردة المعتمدة ISO، واستشارة وراثية مجانية، متوافقة تماماً مع توجيهات هيئة الصحة بدبي 2026 والقانون الاتحادي رقم 41 لسنة 2024.
- ✓ Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified Processing (Cert: INT/EGQ/2509DA/3139).
- ✓ Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection & VIP Mobile Phlebotomy (8 AM – 11 PM, all UAE).
- ✓ Clinical Guidance: Telephonic Post-Test Clinical Guidance by DHA-licensed specialists for precise result interpretation.
- ✓ Insurance: Direct Billing Verification – send your card via WhatsApp to +971 54 548 8731.
- ✓ Legal Compliance: Federal Decree-Law No. 41 of 2024 (Art. 87), CDS Law 2026 (Minors), and UAE PDPL Data Privacy fully observed.
نقبل التأمين الصحي والدفع المباشر. خدماتنا مرخصة تحت ترخيص مرفق 9834453. | We accept all major UAE medical insurance plans.
Clinical Overview
The FOXC2 Gene NGS test examines the entire coding region of the FOXC2 gene to identify disease-causing mutations responsible for lymphedema-distichiasis syndrome, a rare dysmorphology condition characterized by childhood lymphedema and double rows of eyelashes. This NGS-based test replaces older single-exon methods, ensuring highest sensitivity and inclusion of copy number variations, aiding pediatricians, oncologists, and geneticists in definitive diagnosis and lifelong management planning in the UAE. (باختصار: فحص جيني شامل للكشف عن الطفرات الوراثية في جين FOXC2 لإرشاد الخطة العلاجية.)
| Parameter | Our Test | Closest Alternative |
|---|---|---|
| Precision | GOLD 99.9% diagnostic sensitivity; full coding exons + 20 bp flanking splice sites coverage via NGS | Sanger sequencing – limited to point mutations/small indels, may miss large deletions |
| Method | NGS (Next Generation Sequencing) with integrated CNV analysis | Sanger sequencing without CNV detection, lower throughput |
| Turnaround | 3 to 4 Weeks (expedited reporting available) | 4 to 6 Weeks typical |
| Clinical Support | Free genetic counselling + pedigree drafting + post-test telephonic guidance | Often not included |
Physician Insight & Safety Protocol
“As a pediatrician, I understand that awaiting a genetic diagnosis for your child can be deeply worrying. This NGS test provides definitive molecular confirmation of FOXC2-related lymphedema-distichiasis syndrome, empowering you and your medical team to initiate early screening for cardiac, ocular, and lymphatic complications. However, every genetic result must be correlated with detailed clinical evaluation—do not interpret the report in isolation.” — Dr. PRABHAKAR REDDY, DHA License 61713011
⚠ Medication Safety & Exclusion Criteria
Do not discontinue prescribed medication without consulting your doctor.
- Exclusion Criteria: This test is not suitable for standalone fetal diagnosis, preimplantation genetic testing, or asymptomatic minors without clinical indication. Patients who have received a blood transfusion within the last 2 weeks or have an active severe infection should defer sample collection.
- Emergency Red Flags: If your child develops sudden shortness of breath, severe chest pain, sudden vision loss, or rapidly worsening limb swelling, seek immediate medical attention – these may indicate complications like pulmonary embolism or acute lymphatic obstruction.
- Sample collection is performed by DHA-licensed phlebotomists using sterile, single-use equipment. Rare adverse events (bruising, fainting) are managed on-site.
Patient FAQ & Clinical Guidance
1. What is the FOXC2 gene test and who should undergo it?
Direct Clinical Answer: This NGS test detects pathogenic FOXC2 variants causing lymphedema-distichiasis syndrome, recommended for children with leg lymphedema and double eyelashes or a positive family history.
If your child shows swelling of the lower limbs from infancy or early childhood and an extra row of eyelashes (distichiasis), this test confirms the diagnosis. It is also indicated for affected adults planning a family or for cascade screening of relatives. The test requires a prior clinical evaluation and genetic counselling session to draw a family pedigree.
ما هو تحليل جين FOXC2 ومن يجب أن يجريه؟ هذا الفحص الجيني بتقنية NGS يكشف الطفرات المرضية في جين FOXC2 المسببة لمتلازمة الوذمة اللمفية والرموش المزدوجة، ويوصى به للأطفال الذين يعانون من تورم الساقين مع صف إضافي من الرموش أو لمن لديهم تاريخ عائلي.
2. How is the sample collected and what are the pre-test requirements?
Direct Clinical Answer: A simple blood draw, extracted DNA, or one drop of blood on an FTA card is accepted; a genetic counselling session to construct a family pedigree is mandatory before testing.
Our home collection team visits you at a time you choose (8 AM – 11 PM) and obtains the sample using sterile venipuncture or a finger-prick for FTA cards. You must provide a detailed clinical history and attend a free pre-test genetic counselling session (via telemedicine) where the clinical geneticist will draw a pedigree chart. No fasting is required, but we advise postponing if the patient has a fever or has received a recent blood transfusion.
كيف يتم سحب العينة وما هي المتطلبات قبل الفحص؟ تقبل عينة دم أو DNA مستخلص أو قطرة دم على بطاقة FTA، ويشترط قبل الفحص جلسة استشارة وراثية لرسم شجرة العائلة وجمع التاريخ العائلي.
3. How accurate is this test and what is the turnaround time?
Direct Clinical Answer: With 99.9% diagnostic sensitivity and complete NGS coverage of all FOXC2 coding exons, results are available in 3 to 4 weeks.
The ISO-certified laboratory uses the latest Illumina platform and includes copy number variation analysis, which legacy tests miss. The report is issued in a DHA-compliant format with clear interpretation of pathogenic, likely pathogenic, and variants of uncertain significance. A post- telephonic consultation with our clinical team ensures you understand the implications for your child’s care and family planning.
ما مدى دقة هذا الفحص وما هي مدة صدور النتيجة؟ تبلغ الحساسية التشخيصية 99.9% مع تغطية كاملة للإكسونات، وتظهر النتائج خلال 3 إلى 4 أسابيع مع استشارة هاتفية مجانية.
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Schedule your VIP phlebotomy (8 AM – 11 PM) or send your insurance card for direct billing.
WhatsApp: +971 54 548 8731© 2026 UAE Precision Genomics Hub. All services compliant with DHA, MOHAP, Federal Decree-Law No. 41 of 2024, and UAE PDPL. ISO 9001:2015 Cert: INT/EGQ/2509DA/3139.
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توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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