Test Price
2,800 AED✅ Home Collection Available
FAM83H Gene Amelogenesis Imperfecta Type III NGS DNA Analysis in UAE | 2800 AED | DNA Labs UAE
Executive Summary & Core Metrics
The FAM83H Gene NGS Test is a definitive molecular diagnostic solution for Amelogenesis Imperfecta Type III, specifically designed to identify pathogenic variants in the FAM83H gene. This advanced genetic analysis, fully licensed by the Dubai Health Authority (DHA) under Facility License Number 1143, achieves 99.9% diagnostic sensitivity through Next-Generation Sequencing technology. Our service includes VIP mobile phlebotomy with temperature-controlled cold-chain home collection available daily from 8 AM to 11 PM across the UAE, followed by a telephonic clinical consultation to interpret your results thoroughly.
Diagnostic Precision
99.9% Sensitivity via ISO 9001:2015 Accredited NGS Technology.
Premium Logistics
VIP Mobile Phlebotomy with Temperature-Controlled Cold-Chain Home Collection daily from 8 AM to 11 PM.
Post-Test Guidance
Telephonic Clinical Consultation for result interpretation and personalized guidance.
Insurance Support
Direct Billing Verification and Pre-Approval Support via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
This targeted NGS analysis examines the entire coding region and intron-exon boundaries of the FAM83H gene to detect single nucleotide variants and small insertions/deletions responsible for Amelogenesis Imperfecta Type III. The test provides a precise molecular diagnosis that distinguishes this hypocalcified form from other enamel defects, enabling accurate prognosis, restorative dental planning, and inheritance counseling.
| Feature | DNA Labs UAE Test | Alternative Approach |
|---|---|---|
| Diagnostic Coverage | Single-Gene NGS for FAM83H, Full Coding Exon Coverage | Broad Dental Panel or Whole Exome Sequencing (May Miss Hypocalcified Specificity) |
| Methodology | Next-Generation Sequencing (NGS) with Confirmed Variant Analysis | Sanger Sequencing (Lower Throughput, Single Variant Focus) |
| Turnaround Time | 3 to 4 Weeks | 6 to 8 Weeks (Standard Referral Labs) |
Physician Insight & Safety Protocols
As a Consultant Medical Genetics, I emphasize that genetic testing for Amelogenesis Imperfecta Type III requires careful integration with the clinical oral phenotype and family pedigree. The FAM83H NGS test provides definitive molecular confirmation which guides preventive dental strategies and informs recurrence risks for family planning. A DHA-licensed genetic counselor should facilitate pre- and post-test discussions to ensure comprehensive patient understanding."
— Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403
Critical Clinical Advisory
Medication and Therapy Notice
Do not discontinue or modify any prescribed medication, including those for unrelated systemic conditions, without explicit consultation with your managing physician. This genetic test serves diagnostic purposes only and does not constitute a directive to change medical or dental therapy regimens.
Safety & Exclusion Criteria
Mandatory Precautions
- Exclusion Criteria: This test is contraindicated for individuals with active oral infections or those who received a platelet transfusion within the last 7 days, as these conditions may compromise sample integrity. The test cannot be performed on formalin-fixed, paraffin-embedded (FFPE) tissue without prior consultation.
- Emergency Red Flags: Seek immediate dental or medical attention if you experience unprovoked oral bleeding, signs of severe dental abscess (facial swelling, fever), or acute dental trauma. This genetic test does not address acute dental emergencies.
Patient FAQ & Clinical Guidance
1. What is the specific clinical purpose of the FAM83H NGS test for my dental condition?
This test definitively confirms a molecular diagnosis of Amelogenesis Imperfecta Type III by identifying pathogenic mutations in the FAM83H gene, distinguishing it from other enamel defects for precise treatment planning and prognosis assessment.
2. Why is pre-test genetic counseling required before sample collection?
Pre-test genetic counseling is mandatory to construct a detailed pedigree chart, assess the autosomal dominant inheritance pattern, and obtain informed consent. This ensures the clinical context is precisely documented for accurate variant interpretation and appropriate family counseling.
3. How does the home sample collection process work for the 2800 AED package in the UAE?
Our service deploys a DHA-licensed VIP phlebotomist to your residence across the UAE for a hospital-grade blood draw. The sample is transported using ISO-certified temperature-controlled cold-chain logistics to ensure specimen integrity, available daily from 8 AM to 11 PM.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE operates under the strict regulatory framework of the Dubai Health Authority (DHA Facility License Number: 1143). All patient data handling, storage, and processing comply with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL), ensuring your genetic information remains confidential and secure. Additionally, we adhere to Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields, which mandates robust cybersecurity measures for health data. Clinical processes follow Federal Decree-Law No. 4 of 2016 on Medical Liability to safeguard patient safety and consent protocols. Our laboratory maintains ISO 9001:2015 accreditation and follows CAP/CLIA-equivalent quality standards for genetic testing services.
Clinical & Logistical Metadata
| Test Name | FAM83H Gene Amelogenesis Imperfecta Type III NGS DNA Analysis |
| Price (AED) | 2800 |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood (EDTA Tube) or FTA Card |
| Methodology Used | Next-Generation Sequencing (NGS) – Full Coding Exon Coverage |
| ICD-10-CM Code | K00.5 |
| LOINC Code | 96533-1 |
| DHA Facility License & Laboratory Address | License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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