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Test Price

2,800 AED

✅ Home Collection Available

ERCC4 Gene Genetic Test for XFE Progeroid Syndrome in UAE | 2800 AED | DHA Licensed

Executive Summary & Core Metrics

  • Diagnostic Accuracy: 99.9% sensitivity via ISO 9001:2015 accredited processing.
  • Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM.
  • Clinical Guidance: Complimentary telephonic post-test result interpretation by DHA-licensed genetic counselor.
  • Insurance: Direct billing verification via WhatsApp at +971 54 548 8731.

Test Overview & Methodology

The ERCC4 gene encodes a DNA repair protein; pathogenic variants cause XFE progeroid syndrome, a segmental progeroid disorder with prominent skin, immunological, and oncological manifestations. This NGS-based genetic test provides definitive molecular diagnosis and empowers personalized surveillance strategies tailored to each patient.

Attribute Our Test (DNA Labs UAE) Closest Alternative
Method Next Generation Sequencing (NGS) – full gene sequencing & CNV analysis Sanger sequencing of coding exons only
Analytical Sensitivity >99.9% for SNVs/indels ~95% for point mutations; limited CNV detection
Turnaround Time 3–4 weeks 4–6 weeks
Price 2800 AED ~2500 AED (may not include comprehensive analysis)

Physician Insight & Safety Protocols

"As a Consultant Medical Genetics (DHA License 9294403), I, Lina Osama Zaki Quteineh, emphasize that a positive ERCC4 variant is a critical starting point—not an end. Results must be integrated with clinical phenotype and thorough genetic counseling to formulate a lifelong management plan, including dermatological surveillance and cancer screening tailored to the individual's risk."

Medication Advisory

⚠ Do not discontinue any prescribed medication without consulting your doctor. This genetic test does not substitute for ongoing clinical management.

Exclusion Criteria & Red Flags

  • Minors (individuals under 18 years): Testing requires legal guardian consent in full compliance with Federal Decree-Law No. 4 of 2016 on Medical Liability.
  • Bleeding disorders/anticoagulants: Consult your physician before blood draw if you have a known bleeding condition or are on blood thinners.
  • Emergency red flags: If you notice rapid growth of a mole, non‑healing ulcer, unexplained severe fatigue, or signs of systemic infection, seek immediate medical attention.

Patient FAQ & Clinical Guidance

1. What does this genetic test detect?

Detects ERCC4 mutations linked to XFE progeroid syndrome, enabling accurate diagnosis and personalized cancer screening.

2. How is the sample collected?

A blood or FTA card sample is collected at home via VIP Mobile Phlebotomy with cold-chain transport, available daily 8 AM to 11 PM.

3. When will I receive my results and what is the cost?

Results within 3–4 weeks; cost 2800 AED. Insurance direct billing available via WhatsApp.

UAE Regulatory & Data Privacy Adherence

DNA Labs UAE operates under DHA Facility License 1143 and complies with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is handled with strict confidentiality and stored on secure servers within the UAE.

Clinical & Logistical Metadata

Test NameERCC4 Gene Genetic Test for XFE Progeroid Syndrome
Price (AED)2800
Turnaround Time3–4 weeks
Sample Type / MatrixPeripheral whole blood or FTA card
Methodology UsedNext Generation Sequencing (NGS) – full gene sequencing & CNV analysis
ICD-10-CM CodeE34.8
LOINC Code21679-7
DHA Facility License & Laboratory AddressLicense: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE

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