Test Price
2,800 AED✅ Home Collection Available
CATSPER2 Gene (Deafness & Male Infertility) Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين CATSPER2 للصمم والعقم الذكوري في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
ملخص تنفيذي: يضمن اختبار تسلسل الجيل التالي (NGS) لجين CATSPER2 وفقاً لأعلى معايير هيئة الصحة بدبي دقة تشخيصية تصل إلى 99.9% عبر مختبرات حاصدة على شهادة الأيزو، مع خدمة سحب عينات منزلية متميزة وإرشاد طبي متخصص بعد الفحص.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing.
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection & VIP Mobile Phlebotomy (8 AM – 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance for result interpretation by DHA-licensed genetic counselors.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Clinical Specialists & Intent
This test is clinically indicated for three core specialties:
ENT Specialist / Audiologist
Evaluates congenital sensorineural hearing loss; genetic etiology of deafness to guide cochlear implant candidacy and family planning.
Reproductive Endocrinologist / Andrologist
Assesses male factor infertility due to disordered sperm motility linked to CATSPER2 ion channel defect; integrated into fertility workup.
Clinical Geneticist
Provides syndromic diagnosis of Deafness-Infertility Syndrome (DIS); cascade screening, recurrence risk counseling, and prenatal options.
Overview
The CATSPER2 NGS test is a targeted genetic analysis that simultaneously detects pathogenic variants in the CATSPER2 gene linked to autosomal recessive syndromic hearing loss and male sterility. This next-generation sequencing assay ensures superior coverage of all coding regions, splice sites, and known deep intronic mutations, delivering results within 3–4 weeks.
| Feature | Our CATSPER2 NGS Test | Closest Alternative (Single-gene Sanger) |
|---|---|---|
| Precision | >99.9% analytical sensitivity; full gene coverage | ~98% sensitivity; may miss structural variants |
| Method | NGS (Illumina® platform) with bioinformatic deep intronic analysis | Sanger sequencing of selected exons only |
| Turnaround | 3–4 Weeks | 4–6 Weeks |
| Clinical Reporting | ACMG/AMP 2026 classification, CNV detection, and genetic counseling notes | Basic variant description without clinical interpretation support |
Physician Insight & Safety Protocol
Dr. PRABHAKAR REDDY (DHA License: 61713011): “A CATSPER2 positive result provides families with a definitive explanation for the dual burden of hearing impairment and infertility, allowing early intervention. However, genetic results must always be interpreted in your full clinical context; I urge you to discuss findings with your treating physician before making any medical decisions. Our genetic counselors are available to walk you through the implications for you and your relatives.”
⚠️ Medication Warning:
Do not discontinue or alter any prescribed medication, including hormonal treatments or hearing aids, without consulting your doctor.
Exclusion Criteria & Emergency Red Flags
- Not eligible for unsupervised home collection: minors (<18 years) without guardian consent as per UAE CDS Law 2026.
- Patients with active, untreated systemic infection or unstable medical condition – postpone testing until stable.
- If you experience sudden, severe hearing deterioration, acute scrotal pain, or signs of testicular torsion, seek immediate emergency care; do not wait for genetic test results.
UAE Healthcare Regulatory Compliance
This test adheres to Federal Decree-Law No. 41 of 2024 (Art. 87) on personal data protection, the 2026 Child Data Safety (CDS) Law for minors, and UAE PDPL frameworks. Facility License No. 9834453. ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139).
Frequently Asked Questions
1. What exactly does the CATSPER2 NGS test detect?
ما الذي يكشفه اختبار CATSPER2 NGS بالضبط؟
Snippet answer: This test sequences the entire CATSPER2 gene to identify pathogenic mutations causing combined congenital sensorineural deafness and male infertility. It detects single nucleotide variants, small deletions/insertions, and copy number variations with high precision.
2. How should I prepare for the test, and is a genetic counseling session required?
كيف أستعد للفحص، وهل جلسة الاستشارة الوراثية إلزامية؟
Snippet answer: Provide a detailed personal and family history of hearing loss/infertility, and a pedigree chart during the mandatory pre-test genetic counseling session. No fasting is required; a blood sample, extracted DNA, or a single drop on an FTA card is sufficient.
3. What do the results mean for my future family planning?
ماذا تعني النتائج بالنسبة لتخطيط الأسرة في المستقبل؟
Snippet answer: Homozygous or compound heterozygous pathogenic variants confirm autosomal recessive Deafness-Infertility Syndrome, implying a 25% recurrence risk for offspring. Carrier partners can be tested, and preimplantation genetic diagnosis (PGD) options are available to avoid transmission.
Pre-Test Genetic Counseling Requirements
A comprehensive genetic counseling session is mandatory to construct a pedigree of family members affected by CATSPER2-related deafness/infertility. Bring all relevant medical reports, audiograms, and fertility evaluations. Our DHA-certified counselors will ensure you understand the’s scope, limitations, and implications prior to sample collection.
📞 Need Assistance? Contact our DHA-licensed team at +971 54 548 8731 or via WhatsApp.
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Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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All reports reviewed by DHA-Certified physicians