Test Price
2,800 AED✅ Home Collection Available
CATSPER2 Gene (Deafness & Male Infertility) NGS Test in UAE | 2,800 AED
Executive Summary & Core Metrics
- Accuracy Guarantee: >99.9% diagnostic sensitivity through ISO 9001:2015 certified processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (available daily from 8 AM to 11 PM).
- Clinical Guidance: Complimentary telephonic post-test consultation with our Consultant Medical Geneticist, Lina Osama Zaki Quteineh.
- Direct Insurance Billing: Verification and direct billing support via WhatsApp at +971 54 548 8731.
- DHA Licensed Facility: Operated under DHA Facility License No. 1143 at Dubai Healthcare City.
Test Overview & Methodology
This next-generation sequencing (NGS) analysis provides comprehensive coverage of the entire coding region and splice sites of the CATSPER2 gene. This calcium-channel gene is essential for sperm flagellar motility and inner-ear hair cell signal transduction. Pathogenic variants are linked to autosomal recessive non-syndromic sensorineural deafness (DFNB86) and asthenozoospermic male infertility. Our assay includes copy number variant (CNV) detection and is validated according to Federal Decree-Law No. 4 of 2016 on Medical Liability, ensuring high clinical utility for carrier screening, reproductive planning, and precise molecular subtyping.
| Feature | DNA Labs UAE CATSPER2 NGS Test | Standard Sanger Sequencing Alternative |
|---|---|---|
| Technology | NGS – full-gene coverage with CNV detection | Single-gene Sanger (limited to known hotspots) |
| Turnaround Time | 21–28 Business Days | 6–8 Weeks |
| Diagnostic Yield | >99.9% analytical sensitivity & specificity | ~95% for known point mutations only |
| Suitable For | Deafness & infertility work-up, carrier screening | Targeted familial variant confirmation |
Physician Insight & Safety Protocols
“Genetic testing for CATSPER2 provides definitive answers for families facing hearing loss and male infertility, but it requires careful bioinformatic interpretation and correlation with audiological and andrological assessments. At DNA Labs UAE, our closed-loop NGS workflow ensures robust coverage and clinical accuracy. I strongly advise patients to discuss all results with a qualified genetic counsellor before making any irreversible reproductive or clinical decisions.” — Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Pre-Test Advisory
A valid physician referral is required to initiate the CATSPER2 NGS test. Results are clinically validated and delivered directly to your referring doctor. Do not adjust or discontinue any prescribed medication without explicit instruction from your treating physician.
Safety Box – Exclusion & Emergency Red Flags
- Minors: Legal guardian consent and pre-test genetic counselling are mandatory, in adherence with UAE Federal Child Protection Law.
- Pregnancy: Sample collection is safe; however, prenatal genetic diagnosis requires prior approval and a dedicated fetal medicine consultation.
- Acute Infection: Defer blood collection by 7–10 days if you have an active systemic infection to ensure specimen integrity.
- Emergency Red Flags: Sudden unilateral hearing loss, acute tinnitus, or vertigo requires immediate ENT evaluation before proceeding with outpatient genetic testing.
Patient FAQ & Clinical Guidance
1. What specific conditions are linked to the CATSPER2 gene?
Pathogenic variants in CATSPER2 are associated with autosomal recessive non-syndromic sensorineural deafness (DFNB86) and male infertility due to asthenozoospermia, where sperm motility is severely impaired. This NGS test detects single nucleotide variants, indels, and copy number variants across the entire gene.
2. What is the sample collection process for this NGS test?
A certified phlebotomist will collect 3–5 mL of peripheral whole blood in an EDTA tube, or you may provide a dried blood spot on an FTA card. Our VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection service operates daily from 8 AM to 11 PM across Dubai and the Northern Emirates.
3. How does insurance coverage work for this genetic test in the UAE?
DNA Labs UAE provides direct billing for most UAE health insurance policies that cover medically indicated genetic testing. We verify your coverage and provide a cost estimate upfront. Contact our billing team via WhatsApp at +971 54 548 8731 for a pre-authorisation check.
4. What is the turnaround time, and how are results delivered?
Standard turnaround time is 21–28 business days. Results are securely delivered in a PDF format to both the patient and the referring physician, accompanied by a clinical interpretation summary from our Consultant Medical Geneticist.
5. Do I need a doctor’s referral to proceed with this test?
Yes, a valid referral from a licensed medical practitioner is mandatory before sample collection can be scheduled. This ensures that the genetic investigation is clinically indicated and aligns with your overall diagnostic work-up.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE strictly complies with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is encrypted, access-restricted, and processed solely for diagnostic purposes under the direct supervision of our genetics team. Our laboratory operates under DHA Facility License No. 1143 and maintains ISO 9001:2015 certification (Cert: INT/EGQ/2509DA/3139).
Clinical & Logistical Metadata
| Test Name | CATSPER2 Gene (Deafness & Male Infertility) NGS Test |
| Price (AED) | 2,800 |
| Turnaround Time | 21–28 Business Days |
| Sample Type / Matrix | Whole Blood (EDTA) or Dried Blood Spot (FTA Card) |
| Methodology Used | Next-Generation Sequencing (NGS) – Full Gene Coverage & CNV Detection |
| ICD-10-CM Code | H90.5 / N46.0 |
| LOINC Code | 94490-1 |
| DHA Facility License & Laboratory Address | DHA License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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