Test Price
2,800 AEDโ Home Collection Available
CA12 Gene Hyperchlorhidrosis, Isolated Genetic Test in UAE | 2,800 AED | DHA Licensed
Executive Summary & Core Metrics
Diagnostic Sensitivity
99.9% via ISO-accredited Next-Generation Sequencing with orthogonal Sanger confirmation.
Home Collection Available
VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection, daily from 8 AM to 11 PM.
Post-Test Counselling
Telephonic interpretation by a Consultant Medical Geneticist familiar with metabolic genetics.
Insurance Billing
Verify coverage via WhatsApp +971 54 548 8731 before collection.
Test Overview & Methodology
The CA12 Gene Hyperchlorhidrosis, Isolated Genetic Test analyses the entire coding region of the CA12 gene for disease-causing variants linked to isolated hyperchlorhidrosis, a rare metabolic disorder affecting sweat chloride regulation. This test is essential for definitive diagnosis, family screening, and genetic counselling.
| Feature | Our Test (NGS Full Gene Sequencing) | Closest Alternative (Targeted Mutation Panel) |
|---|---|---|
| Methodology | Next-Generation Sequencing (NGS) with Sanger confirmation | Limited to known hotspot mutations |
| Analytical Sensitivity | 99.9% (identifies novel variants) | ~85% (misses rare/private mutations) |
| Turnaround Time | 3โ4 Weeks | 1โ2 Weeks |
| Clinical Utility | Gold standard for index cases & family screening | Only for known familial variant tracking |
| Included | Pre-test genetic counselling & pedigree charting | Not included |
Physician Insight & Safety Protocols
โThis NGS test provides a comprehensive molecular view of the CA12 gene, essential for diagnosing isolated hyperchlorhidrosis. However, the results must be interpreted alongside your clinical history and family pedigree for accurate clinical correlation. Do not alter any prescribed treatments without consulting your doctor.โ
โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
โ Important Safety Advisory
Do not stop or change any prescribed medication without approval from your treating physician. This test is designed for diagnostic purposes only and does not replace acute medical care.
Exclusion Criteria & Red Flags
- Acute febrile illness or systemic infection โ delay testing until full recovery.
- Pregnancy โ genetic counselling must be provided and informed consent obtained before proceeding.
- Inability or unwillingness to provide a three-generation family pedigree.
- Seek emergency care if you experience: sudden severe muscle cramps, intractable vomiting, or altered consciousness โ these may indicate severe electrolyte imbalance.
All patients undergo a mandatory pre-test genetic counselling session to document clinical history and construct a detailed pedigree of affected family members.
Patient FAQ & Clinical Guidance
1. Why is NGS sequencing of the CA12 gene preferred for isolated hyperchlorhidrosis?
Full-gene NGS reads every coding base of the CA12 gene, capturing both known and novel mutations with 99.9% diagnostic sensitivity. This approach outperforms targeted panels that only detect pre-selected variants, making it the gold standard for index cases and family screening.
2. How long does the result take and how will I receive it?
Your integrated report, including variant interpretation and clinical correlation, is delivered within 3 to 4 weeks via our secure online portal. A telephonic review with a consultant geneticist can be scheduled at no additional cost.
3. What sample is required and is home collection safe?
A single peripheral blood draw or one drop of blood on an FTA card is sufficient. Our VIP Mobile Phlebotomy service uses ISO-certified cold-chain logistics to preserve DNA integrity and ensure safe, convenient collection at your home.
UAE Regulatory & Data Privacy Adherence
Data Protection and Compliance
This test is conducted under the regulatory framework of the Dubai Health Authority (DHA) and complies with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is encrypted, stored securely, and used solely for diagnostic purposes with your explicit consent. Clinical safety and patient consent procedures adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability.
Clinical & Logistical Metadata
| Test Name | CA12 Gene Hyperchlorhidrosis, Isolated Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3โ4 Weeks |
| Sample Type / Matrix | Whole Blood (PBMC) or Dried Blood Spot on FTA Card |
| Methodology Used | Next-Generation Sequencing (NGS) with Sanger confirmation |
| ICD-10-CM Code | E88.8 (Other specified metabolic disorders) |
| LOINC Code | 48000-0 (CA12 gene sequencing) |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE โ DNA Labs UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians