Test Price
2,800 AED✅ Home Collection Available
B4GALNT1 Gene SPG26 Genetic Test in UAE | 2,800 AED | 2026 DHA Guidelines
تحليل الجين B4GALNT1 (SPG26) بتقنية التسلسل الجيني NGS في الإمارات | 2,800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary – Accuracy, Privacy & UAE-Compliant Genetic Testing
- Diagnostic Precision: 99.9% analytical sensitivity for pathogenic B4GALNT1 variants via ISO‑certified NGS.
- Premium Home Collection: Hospital‑grade cold‑chain phlebotomy (8 AM – 11 PM) across Dubai, Abu Dhabi, and all Emirates.
- Clinical Interpretation: Post‑test telephonic guidance with a DHA‑licensed neurologist, ensuring safe result integration.
- Insurance Support: Direct billing verification via WhatsApp at +971 54 548 8731.
الملخص التنفيذي — دقة وخصوصية وامتثال كامل لقوانين الفحص الجيني في دولة الإمارات العربية المتحدة. يضمن فحصنا حساسية تشخيصية بنسبة 99.9% للطفرات المرضية في الجين B4GALNT1، مع خدمة جمع عينات منزلية معتمدة بتقنية سلسلة التبريد المعقّمة، وتوجيه سريري هاتفي بعد الفحص، والتحقق المباشر من التأمين عبر واتساب.
Comprehensive Gene Test for Hereditary Spastic Paraplegia Type 26 (SPG26)
This next‑generation sequencing (NGS) assay targets the entire B4GALNT1 gene to diagnose autosomal recessive SPG26, a progressive upper motor neuron disorder. The test is indicated for patients with clinical spastic paraplegia, family history, or carrier testing, and delivers definitive molecular confirmation in as fast as 3–4 weeks.
| Feature | Our B4GALNT1 NGS Test | Standard Single‑Gene Sanger Sequencing |
|---|---|---|
| Mutation Coverage | Full gene (coding exons ± flanking intronic regions), detects SNVs, small indels, and copy‑number variations if designed | Limited to targeted amplicons; may miss deep intronic or regulatory variants |
| Sensitivity | >99.9% for pathogenic variants within covered regions | ~99% for specific point mutations, low detection of large rearrangements |
| Turnaround Time | 3–4 weeks | 4–6 weeks (often requires MLPA add‑on for deletions) |
Clinical Insight from DHA‑Licensed Neurology Consultant
“A positive B4GALNT1 result must always be correlated with the patient’s clinical picture and family history. This test is a powerful tool for confirming SPG26, but it is not a substitute for a complete neurological evaluation and genetic counselling.”
— Dr. PRABHAKAR REDDY, Consultant Neurologist (DHA License: 61713011)
MEDICATION SAFETY WARNING
Do not discontinue any prescribed medication or alter your treatment plan based solely on this genetic test result. Always consult your treating physician prior to making changes.
Exclusion Criteria & ER Red Flags
- Exclusion Criteria: Inability to give informed consent; uncontrolled bleeding diathesis precluding safe venipuncture; known allergy to antiseptic agents used in phlebotomy.
- Urgent Red Flags: If you experience acute neurological worsening (sudden vision loss, severe headache, breathing difficulty, or paralysis) before the blood collection, proceed to the nearest emergency department immediately; inform the home collection team only after stabilization.
Frequently Asked Questions
1. What does the B4GALNT1 genetic test diagnose?
This advanced NGS test accurately identifies B4GALNT1 gene mutations to definitively diagnose hereditary spastic paraplegia type 26 (SPG26). It confirms the genetic cause behind progressive leg stiffness, gait difficulties, and possible bladder involvement, guiding targeted management and family risk assessment.
2. كيف يتم إجراء اختبار الجين B4GALNT1 في الإمارات؟
يتم سحب عينة دم بسيطة من المنزل بواسطة فريق تمريض معتمد بتقنية سلسلة التبريد، ثم تُحلل بتقنية التسلسل الجيني المتقدّم (NGS) لتحديد الطفرات المسببة لمرض الشلل التشنجي الوراثي من النوع 26. تظهر النتائج خلال 3-4 أسابيع مع جلسة إرشاد وراثي هاتفية شاملة.
3. Is a genetic counselling session required before testing?
Yes, pre‑test genetic counselling is mandatory to draw a pedigree and discuss implications before the B4GALNT1 NGS. Our tele‑counselling service meets UAE PDPL and CDS Law requirements, ensuring informed consent, family history mapping, and clear expectation setting for results that may affect at‑risk relatives.
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توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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