Test Price
2,800 AEDโ Home Collection Available
AVP Gene (Arginine Vasopressin) Neurohypophyseal Diabetes Insipidus Genetic Test (NGS) in UAE | 2800 AED
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation by DHA-licensed physician.
- Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
This genetic test uses Next Generation Sequencing (NGS) to evaluate the AVP gene for inherited mutations that cause familial neurohypophyseal diabetes insipidus, enabling definitive diagnosis, targeted treatment planning, and cascade family screening. The analysis covers the entire coding region and splice sites, with detection of copy number variants (CNVs) according to current ACMG guidelines.
| Feature | Our Test (AVP NGS) | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Precision | Full coding region and splice sites, detection of copy number variants (CNVs) | Limited to targeted exons, may miss deep intronic or regulatory variants |
| Methodology | Next Generation Sequencing (NGS) with bioinformatics validated against clinical databases | Classical Sanger Sequencing |
| Turnaround Time | 3 to 4 Weeks | 2 to 3 Weeks (narrower scope) |
Physician Insight & Safety Protocols
โAs a DHA-licensed Consultant Medical Geneticist, I emphasize that the AVP gene test is a powerful tool when correlated with clinical symptoms, water deprivation test results, and family history. A positive result confirms hereditary neurohypophyseal diabetes insipidus and guides family screening, while a negative result does not exclude acquired or nephrogenic forms. Comprehensive post-test genetic counseling is essential and is provided as part of this service.โ
โ Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403
Advisory & Safety Precautions
Important Advisory:
Genetic results may reveal carrier status or predisposition for family members. It is strongly recommended that you undergo pre- and post-test genetic counseling. Do not make any changes to current medical management without consulting your physician.
Exclusion Criteria & Emergency Red Flags
Exclusion Criteria
- No pre-test genetic counselling session completed.
- Active febrile illness or acute water imbalance crisis requiring immediate emergency care.
- Inability to provide informed consent; minors must be accompanied by a legal guardian per UAE Personal Data Protection Law (PDPL) and Federal Law No. 2 of 2019.
Emergency Red Flags (Seek Immediate Medical Attention)
- Severe dehydration, altered mental status, or seizure.
- Hypernatremia >150 mmol/L or rapid electrolyte shifts.
- Unexplained hypotension or oliguria in a known diabetes insipidus patient.
Patient FAQ & Clinical Guidance
1. What is the AVP gene test for?
The AVP gene test detects mutations causing neurohypophyseal diabetes insipidus, enabling accurate diagnosis and genetic counseling. This test specifically targets inherited changes in the arginine vasopressin gene, which can lead to central diabetes insipidus with an autosomal dominant or recessive pattern. It is recommended for individuals with polyuria, polydipsia, and a family history of the condition, helping to differentiate from nephrogenic or primary polydipsia disorders.
2. What sample is required?
A small blood sample, extracted DNA, or a dried blood spot on an FTA card is sufficient. You may provide a standard venipuncture sample (whole blood in EDTA tube), previously extracted DNA, or a single drop of blood dried on an FTA card, which enables stable transport at ambient temperature. The pre-test genetic counselling session will confirm the appropriate sample type for your situation.
3. How long do results take?
Results are available within 3 to 4 weeks, with post-test clinical guidance after genetic counseling. The NGS workflow, including library preparation, sequencing, and bioinformatics interpretation under current ACMG criteria, takes a standard 3โ4 weeks. Upon result delivery, a DHA-licensed physician provides a telephonic explanation and, if needed, coordinates further management with endocrinologists or geneticists.
UAE Regulatory & Data Privacy Adherence
This genetic test is performed in compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All patient data are encrypted, access-controlled, and used solely for diagnostic purposes. Clinical safety and patient consent procedures adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. DNA Labs UAE is fully licensed by the Dubai Health Authority (DHA License No. 1143).
Clinical & Logistical Metadata
| Test Name | AVP Gene (Arginine Vasopressin) Neurohypophyseal Diabetes Insipidus Genetic Test (NGS) |
| Price (AED) | 2,800 |
| Turnaround Time | 3โ4 Weeks |
| Sample Type / Matrix | Whole Blood (EDTA), Extracted DNA, or Dried Blood Spot (FTA Card). VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily 8 AM โ 11 PM. |
| Methodology Used | Next Generation Sequencing (NGS) with bioinformatics analysis |
| ICD-10-CM Code | E23.2 |
| LOINC Code | 89283-2 |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
ุฏุนู ุซูุงุฆู ุงููุบุฉ ู ุชุงุญ
ุงูุชุญูู ู ู ุงูุชุบุทูุฉ ุงูุชุฃู ูููุฉ
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
ุชููู ุนู ุงูุชุฎู ูู. ุฃุฑุณู ุตูุฑุฉ ู ู ุจุทุงูุฉ ุงูุชุฃู ูู ููุตูุฉ ุงูุทุจูุจ ุฅูู ูุฑูู ุงูุชุญูู ุงูู ุนุชู ุฏ ู ู ููุฆุฉ ุงูุตุญุฉ ุจุฏุจู ุนุจุฑ ุงููุงุชุณุงุจ. ุงุญุตู ุนูู ุชุญุฏูุซ ุงูุญุงูุฉ ูู ุฏูุงุฆู.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians