Test Price
2,800 AED✅ Home Collection Available
ALDH18A1 Gene (Cutis Laxa Type 3A, Autosomal Recessive) Genetic Test in UAE
Executive Summary & Core Metrics
Executive Summary
- Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO 9001:2015 accredited Next Generation Sequencing.
- Premium Logistics: Complimentary VIP mobile phlebotomy and temperature-controlled cold-chain home collection by DHA-licensed phlebotomists (8 AM–11 PM daily).
- Clinical Guidance: Post-test genetic counselling teleconsultation included to interpret results and plan next steps.
- Insurance: Direct billing verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The ALDH18A1 gene genetic test analyzes the entire coding region of the ALDH18A1 gene using advanced Next Generation Sequencing (NGS) to definitively diagnose autosomal recessive cutis laxa type 3A (ARCL3A). This rare connective tissue disorder is characterized by loose, inelastic skin, joint hypermobility, and developmental delay. The test provides molecular confirmation that guides personalised management, family planning, and early intervention.
| Parameter | Our Test – Premium NGS | Closest Alternative – Single Gene Sequencing |
|---|---|---|
| Coverage | Full ALDH18A1 gene (all exons and flanking regions) | Selected hotspots/exons only; may miss deep intronic variants |
| Sensitivity | >99.9% (NGS with >1000x depth) | ~85–90% for targeted regions |
| Turnaround Time | 3–4 Weeks | 6–8 Weeks |
| Price in UAE | 2,800 AED | 2,500–3,200 AED (often with add-on charges) |
Physician Insight & Safety Protocols
“As a Consultant Medical Genetics specialist, I understand the uncertainty when cutis laxa is suspected. This test provides definitive molecular answers; a positive result is a roadmap, not a verdict. Multidisciplinary care, started early, markedly improves quality of life.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Exclusion Criteria & Emergency Red Flags
- Exclusion: Patients with severe coagulopathy or uncontrolled bleeding disorders must consult the lab before blood collection.
- Red Flag – Seek Immediate Medical Care: If the individual experiences acute respiratory distress, chest pain, or sudden vascular events (e.g., arterial dissection) – do not wait for test results; visit the nearest emergency department.
- This test is not intended for standalone diagnosis; clinical correlation with a geneticist or dermatologist is mandatory.
Medication Advisory
Do not discontinue any prescribed medication without consulting your physician. This genetic test does not replace ongoing medical treatment.
Patient FAQ & Clinical Guidance
1. What does the ALDH18A1 genetic test diagnose?
This test definitively diagnoses autosomal recessive cutis laxa type 3A by detecting disease-causing mutations in the ALDH18A1 gene.
2. How is the sample collected and what is the turnaround time?
A simple blood sample is drawn by a DHA-licensed phlebotomist via VIP mobile phlebotomy at your home. Results are finalized within 3–4 weeks.
3. Is this test covered by insurance in the UAE?
Many UAE insurance plans cover this test. Contact our billing team via WhatsApp at +971 54 548 8731 to verify your coverage instantly.
4. What is the importance of post-test genetic counselling?
Genetic counselling helps you understand the implications of the results for you and your family, including recurrence risks and management options.
5. Is the test safe if I am pregnant or breastfeeding?
The test is safe as it involves only a simple blood draw. However, please inform your phlebotomist and genetic counsellor if you are pregnant or breastfeeding.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance
- Fully compliant with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
- Clinical testing safety and patient consent adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability.
- All personal health data is processed in accordance with UAE PDPL regulations.
- ISO 9001:2015 Certified – Certificate INT/EGQ/2509DA/3139.
- DHA Facility License Number: 1143.
Clinical & Logistical Metadata
| Test Name | ALDH18A1 Gene (Cutis Laxa Type 3A, Autosomal Recessive) Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole Blood (Peripheral Venous) – VIP mobile phlebotomy & temperature-controlled cold-chain home collection |
| Methodology Used | Next Generation Sequencing (NGS) – Full gene sequencing with >1000x depth |
| ICD-10-CM Code | Q82.8 |
| LOINC Code | 21639-0 |
| DHA Facility License & Laboratory Address | DHA License No. 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE (DNA Labs UAE) |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
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