Test Price
2,800 AED✅ Home Collection Available
ALAS2 Gene Anemia, Sideroblastic, X-Linked Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified NGS Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in Result Interpretation by DHA-Licensed Specialists.
- Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The ALAS2 NGS test sequences the entire coding region of the ALAS2 gene to identify pathogenic variants responsible for X-linked sideroblastic anemia, a rare inherited disorder of heme synthesis. This definitive molecular diagnostic tool guides treatment planning and family risk assessment.
| Aspect | Our NGS Test (ALAS2 Full Gene) | Closest Alternative (Single-Exon Sanger / Biochemical) |
|---|---|---|
| Precision | >99.9% analytical sensitivity for all coding variants (SNVs, indels, CNVs) | 95–98% for targeted exons; misses deep intronic and copy-number changes |
| Methodology | Next Generation Sequencing (NGS) with confirmatory Sanger for pathogenic calls | Sanger sequencing of selected exons or enzyme/protoporphyrin assays |
| Turnaround Time | 3–4 weeks with comprehensive clinical report | 2–6 weeks (often longer for full gene by fragmented testing) |
| Clinical Utility | Definitive molecular diagnosis, family screening, and genetic counseling | Partial information; may require sequential testing |
Physician Insight & Safety Protocols
“As a Consultant Medical Genetics, I understand the uncertainty a suspected hereditary anemia brings to families. This NGS test provides definitive molecular proof, but must be correlated with iron studies and bone marrow evaluation to guide therapy. Our multidisciplinary team supports you from pre-test counseling through result explanation.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory & Medication Safety
⚠️ Do Not Discontinue Prescribed Medication
Always consult your doctor before stopping or altering any prescribed treatment, especially iron chelation or pyridoxine therapy.
Patient Safety & Exclusion Criteria
- Active infection or acute inflammatory state that may alter blood indices prior to collection.
- Known bleeding disorder or severe thrombocytopenia (platelets < 30 × 10⁹/L) – special precautions required.
- Inability to provide informed consent or absence of a legal guardian for minors (mandated by Federal Decree-Law No. 4 of 2016 on Medical Liability).
- Recent blood transfusion within 4 weeks; if unavoidable, note in requisition.
Emergency Red Flags – Seek Immediate Medical Attention:
- Sudden chest pain, palpitations, or severe shortness of breath.
- Pallor with fainting or altered consciousness.
- High-grade fever or signs of severe hemolysis (dark urine, jaundice).
Patient FAQ & Clinical Guidance
1. What conditions does the ALAS2 gene test diagnose?
This test diagnoses X-linked sideroblastic anemia by detecting ALAS2 gene mutations, confirming hereditary microcytic hypochromic anemia with ringed sideroblasts.
2. How is the sample collected and when will I receive results?
A simple blood sample is collected at home by a certified phlebotomist through our VIP mobile phlebotomy service, with results delivered in 3–4 weeks via secure email.
3. Is genetic counseling required before testing?
Yes, pre-test genetic counseling is mandatory in the UAE to draw a pedigree chart and discuss implications, in compliance with DHA regulations.
UAE Regulatory & Data Privacy Adherence
Data Privacy & Security: This service complies with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is encrypted, stored securely, and never shared without explicit consent.
Quality Certification: ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139) ensures rigorous quality management across all laboratory processes.
Clinical & Logistical Metadata
| Test Name | ALAS2 Gene Sequencing (X-Linked Sideroblastic Anemia) – NGS |
| Price (AED) | 2,800 |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Peripheral whole blood (2–5 mL EDTA) |
| Methodology Used | Next Generation Sequencing (NGS) with Sanger confirmation |
| ICD-10-CM Code | D64.0 (Hereditary sideroblastic anemia) |
| LOINC Code | 81321-9 (ALAS2 gene mutation analysis in blood) |
| DHA Facility License & Laboratory Address | License No. 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians