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2,800 AED

✅ Home Collection Available

ADAMTSL4 Gene Ectopia Lentis (Isolated, Autosomal Recessive) Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines

تحليل جين ADAMTSL4 للانتباذ العدسي المعزول المتنحي الجسدي في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي

ضمان الدقة: حساسية تشخيصية تبلغ 99.9% عبر مختبر حائز على شهادة ISO 9001:2015 ومعتمد من هيئة الصحة بدبي.

خدمة منزلية متميزة: سحب دم على مستوى المستشفيات منزلياً بواسطة فريق تمريض متنقل (VIP) مع سلسلة تبريد معتمدة دولياً.

استشارة سريرية: توجيه طبي هاتفي بعد الفحص لتفسير النتائج بإشراف أخصائي عيون واستشاري وراثة سريرية.

التأمين: تحقق مباشر من التغطية التأمينية عبر واتساب: +971 54 548 8731.

Test Overview

The ADAMTSL4 next‑generation sequencing (NGS) test identifies pathogenic variants in the ADAMTSL4 gene causing isolated autosomal recessive ectopia lentis – a dislocation of the eye’s lens that can lead to severe vision loss. Using 100% coding region coverage and high‑depth analysis, this assay delivers clinically actionable results within 3‑4 weeks and includes pre‑test genetic counselling.

Feature Our Test Closest Alternative
Methodology NGS (Coverage ≥100×, CNV analysis) Sanger sequencing of selected exons
Turnaround Time 3–4 weeks 6–8 weeks
Pre‑test Genetic Counselling Included (compulsory) Often separate or not offered
Report Detail Full variant interpretation & pedigree Binary positive/negative only

Clinical Insight & Safety Precautions

“A single gene test like ADAMTSL4 must always be correlated with a meticulous slit‑lamp examination, intraocular pressure measurement, and detailed family history. A positive result confirms the genetic diagnosis but does not fully predict the timing or severity of lens dislocation; a negative result in a highly suggestive phenotype calls for broader genomic testing and further genetic counselling. Please discuss all results with your ophthalmologist and clinical geneticist before making any decisions about surgery or surveillance.”

— Dr. PRABHAKAR REDDY, DHA License: 61713011

⚠️ Do not discontinue any prescribed medication without consulting your doctor.

Safety Exclusion Criteria & Emergency Indicators

  • Exclusion: Acute febrile illness, recent blood transfusion (within 4 weeks).
  • Exclusion (CDS Law 2026): Minors (<18 years) without legal guardian consent; non‑consenting individuals.
  • Red Flag Symptoms – Seek Emergency Care, Not Genetic Testing: Sudden onset of blurred vision, severe eye pain, acute glaucoma attack, or lens dislocation into the anterior chamber. These warrant immediate ophthalmic emergency attention.

Preparation & Pre‑Test Requirements

  • Clinical History Form: Provide detailed ocular and systemic medical history.
  • Genetic Counselling Session (Included): A mandatory session will construct a three‑generation pedigree chart of all family members known to be affected by ectopia lentis or suspicious lens changes. This is performed prior to sample collection.
  • Sample Type: Whole blood – no fasting required. Continue regular medications; inform the team if you have received a blood transfusion in the last month.

Patient Frequently Asked Questions

What does a positive ADAMTSL4 test result mean?

A positive result indicates you carry two pathogenic variants in the ADAMTSL4 gene, confirming the diagnosis of isolated autosomal recessive ectopia lentis and providing a clear basis for personalised ophthalmologic surveillance and family planning.

Is home blood collection available across the UAE?

Yes, our DHA‑licensed mobile phlebotomy team provides hospital‑grade home draws in Dubai, Abu Dhabi, Sharjah, and all Northern Emirates from 8 AM to 11 PM daily, using validated cold‑chain logistics to our ISO‑certified central laboratory.

هل يغطي التأمين هذا الفحص الجيني؟

نعم، نوفر التحقق المباشر من وثيقة التأمين عبر واتساب، وسنقوم بتقديم الفاتورة مباشرة لشركات التأمين المعتمدة في الإمارات إذا كانت التغطية تشمل الفحوصات الجينية التشخيصية.

UAE Regulatory Compliance: All testing is conducted in accordance with Federal Decree‑Law No. 41 of 2024 (Art. 87), the UAE Personal Data Protection Law (PDPL), and the CDS Law 2026 for minors. Facility License: 9834453. Laboratory certified ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139).

Clinical Intent: This is designed for diagnostic confirmation under the supervision of a Specialist Ophthalmologist, a Clinical Geneticist, or a Medical Researcher. Results must be interpreted with clinical context.

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