Test Price
2,800 AED✅ Home Collection Available
SLC45A2 Gene Sequencing for Oculocutaneous Albinism Type 4 (OCA4) – Genetic Test in UAE
Executive Summary & Core Metrics
The SLC45A2 gene sequencing test employs Next-Generation Sequencing (NGS) with 99.9% diagnostic sensitivity for detecting pathogenic variants associated with Oculocutaneous Albinism Type 4 (OCA4). This ISO 9001:2015 accredited assay is performed at our DHA-licensed laboratory in Dubai Healthcare City. Logistics include VIP Mobile Phlebotomy with temperature-controlled cold-chain home collection, available daily from 8 AM to 11 PM. Post-test telephonic clinical guidance is provided by a Consultant Medical Genetics specialist. Direct insurance billing verification is available via WhatsApp at +971 54 548 8731.
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (daily 8 AM – 11 PM).
Clinical Guidance: Telephonic Post-Test Clinical Guidance by Consultant Medical Genetics.
Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The SLC45A2 gene sequencing test utilizes Next-Generation Sequencing (NGS) to detect clinically significant variants associated with Oculocutaneous Albinism Type 4 (OCA4), a genetic disorder characterized by reduced melanin biosynthesis, leading to vision abnormalities, skin and hair hypopigmentation, and increased skin cancer risk. This molecular diagnostic assay provides accurate confirmation of OCA4, enabling targeted ophthalmologic surveillance, dermatologic monitoring, and precise genetic counseling for affected individuals and their families.
| Feature | Our Test (DNA Labs UAE, DHA-licensed) | Closest Alternative |
|---|---|---|
| Precision | NGS full gene sequencing with CNV analysis, 99.9% diagnostic sensitivity | Targeted variant panels missing rare SLC45A2 mutations |
| Methodology | ISO 9001:2015 NGS (Illumina platform) | Sanger sequencing (limited throughput) |
| Turnaround Time | 3–4 Weeks (steady, uncompromised quality) | 6–8 Weeks or longer |
Physician Insight & Safety Protocols
“As a Consultant Medical Genetics specialist at DNA Labs UAE, I confirm that SLC45A2 gene sequencing is the definitive molecular tool for diagnosing Oculocutaneous Albinism Type 4. This NGS-based assay detects pathogenic variants across the entire coding region with high sensitivity, enabling accurate carrier detection and informed family planning. However, a negative result does not exclude all forms of albinism; comprehensive clinical evaluation by an ophthalmologist and dermatologist remains essential for complete patient management.” — Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Safety Advisory
This genetic test is intended for diagnostic confirmation of OCA4 only. Do not modify any prescribed vision therapy, dermatologic treatment, or systemic medication based on test results without first consulting your managing physician. All clinical decisions must be made in coordination with your healthcare provider.
Exclusion Criteria & Emergency Red Flags
- This test is not indicated for asymptomatic minors without a documented family history of OCA4 or a confirmed genetic diagnosis in a first-degree relative, in accordance with ethical guidelines for pediatric genetic testing.
- Inadequately preserved blood or DNA samples (hemolysis, repeated freeze-thaw cycles) will be rejected for processing.
- Emergency Red Flag: Sudden vision loss, intense ocular pain, or acute photophobia requires immediate ophthalmic emergency care.
- Emergency Red Flag: Rapidly changing skin lesions, bleeding moles, or new concerning pigmented lesions require urgent dermatologic evaluation.
- Prenatal testing requires formal genetic counseling and written informed consent; contact our clinical genetics team for pre-test consultation.
Patient FAQ & Clinical Guidance
1. What is the SLC45A2 gene test and who should consider it?
This NGS test confirms oculocutaneous albinism type 4 diagnosis, enabling tailored vision care, skin cancer prevention, and precise familial risk assessment. It is recommended for individuals with hypopigmentation and visual deficits, as well as relatives of known OCA4 patients seeking carrier status.
2. How is the sample collected and what is the turnaround time?
We provide VIP Mobile Phlebotomy with temperature-controlled cold-chain home collection, available daily from 8 AM to 11 PM. A standard peripheral whole blood sample (EDTA tube) is collected by our trained nursing team. Complete results are available within 3 to 4 weeks from sample receipt at our DHA-licensed laboratory.
3. Is this test covered by UAE health insurance?
Yes, many UAE insurers cover genetic testing for albinism when medically indicated. We provide direct billing verification via WhatsApp at +971 54 548 8731. Always confirm eligibility with your insurance provider before sample collection.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE operates under DHA Facility License Number 1143 and adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) for all genetic data handling. Our laboratory information systems comply with Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All clinical testing and patient consent procedures follow Federal Decree-Law No. 4 of 2016 on Medical Liability. Your genetic data is encrypted, access-controlled, and processed exclusively within UAE jurisdiction.
Clinical & Logistical Metadata
| Test Name | SLC45A2 Gene Sequencing for Oculocutaneous Albinism Type 4 (OCA4) |
| Price (AED) | 2,800 |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood (EDTA Tube) |
| Methodology Used | Next-Generation Sequencing (NGS) – Illumina Platform |
| ICD-10-CM Code | E70.319 |
| LOINC Code | 94231-1 |
| DHA Facility License & Laboratory Address | License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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