Test Price
2,800 AED✅ Home Collection Available
RET Gene (Exons 5, 8, 10, 11, 13–16) Selective Sequencing (NGS) in UAE | 2800 AED
Executive Summary & Core Metrics
- Diagnostic Accuracy: 99.9% sensitivity with ISO 9001:2015 certified laboratory processes (Certificate INT/EGQ/2509DA/3139).
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection – available daily from 8 AM to 11 PM across all Emirates.
- Clinical Guidance: Post-test teleconsultation with a consultant medical geneticist for result interpretation and personalised risk management.
- Insurance Support: Direct coverage verification and billing assistance via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The RET gene selective sequencing test uses next‑generation sequencing (NGS) to analyse coding exons 5, 8, 10, 11, and 13–16. It detects germline mutations associated with multiple endocrine neoplasia type 2 (MEN2) syndromes and hereditary medullary thyroid carcinoma. This assay is designed for oncologists, endocrinologists, and genetic counsellors, delivering actionable risk stratification with 99.9% diagnostic sensitivity under UAE clinical standards.
| Feature | DNA Labs UAE RET NGS Test | Closest Alternative (PCR/Sanger) |
|---|---|---|
| Precision | NGS with exon‑level resolution, variant allele frequency quantification | Limited to single‑nucleotide changes; misses large rearrangements |
| Method | Next‑Generation Sequencing (Illumina platform, paired‑end reads) | Sanger sequencing or targeted PCR panels |
| Turnaround | 3–4 Weeks (expedited wet‑lab & bioinformatics pipeline) | 2–5 Weeks (often fragmented workflow) |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA Registration ID: 9294403): “A positive RET mutation result is not a cancer diagnosis; it is a carefully calibrated genetic signal that guides vigilant surveillance and, when indicated, prophylactic thyroidectomy. Every patient’s journey must integrate detailed family history, endocrine evaluation, and shared decision‑making. I emphasise that genomic findings are one piece of a larger clinical mosaic.”
⚠️ Advisory: Medication Continuation & Clinical Management
Do not discontinue any prescribed medication without consulting your treating physician. Genetic test results do not override ongoing clinical care. Always follow the advice of your healthcare provider regarding medications and therapies.
Exclusion Criteria & Emergency Red Flags
- This test is not intended for acute diagnostic triage. If you experience sudden neck swelling, difficulty breathing, severe diarrhea, or suspected hypertensive crisis, proceed to the nearest emergency department immediately.
- Minors require documented consent in accordance with Federal Decree‑Law No. 4 of 2016 on Medical Liability; testing in asymptomatic children must be authorised by a DHA‑licensed genetic counsellor.
- Recent blood transfusion (within 2 weeks) or active hematological malignancy may interfere with germline DNA extraction. Inform the phlebotomy team about any recent medical events.
- This assay cannot rule out somatic RET mutations in tumour tissue; it is strictly a constitutional (germline) test.
Patient FAQ & Clinical Guidance
1. What does a positive RET gene result mean for my health?
A positive result indicates you carry a germline RET mutation that increases lifetime risk for medullary thyroid carcinoma and MEN2‑associated tumours. However, risk does not equal disease; your oncologist will create a personalised screening plan that may include annual calcitonin monitoring and thyroid ultrasound.
2. How is the sample collected, and is home service available?
Our ISO‑certified home collection team draws a standard venous blood sample or accepts a dried blood spot on an FTA card. We offer VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection from 8 AM to 11 PM across all Emirates, maintaining specimen integrity until it reaches our NGS facility.
3. Are my genetic data kept confidential under UAE law?
Absolutely; all genetic information is protected by Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and processed within ISO‑certified secure infrastructure. Results are shared only with the ordering physician and the patient via encrypted channels, never with insurers or employers without explicit consent.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE complies fully with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data are processed in secure, ISO‑certified environments and are never disclosed to third parties without your explicit, written consent. Clinical testing safety and patient consent abide by Federal Decree‑Law No. 4 of 2016 on Medical Liability. Your privacy and safety are our highest priorities.
Clinical & Logistical Metadata
| Test Name | RET Gene (Exons 5, 8, 10, 11, 13–16) Selective Sequencing (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Peripheral whole blood (3‑5 mL in EDTA tube) or dried blood spot on FTA card |
| Methodology Used | Next‑Generation Sequencing (Illumina, paired‑end reads) |
| ICD-10-CM Code | Z13.89 (Encounter for screening for other genetic disorders) |
| LOINC Code | 92815-9 (RET gene mutation analysis) |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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