Test Price
2,800 AED✅ Home Collection Available
RNASEH2A Gene Sequencing for Aicardi-Goutières Syndrome Type 4 | 2800 AED | 2026 DHA Guidelines
تحليل جين RNASEH2A لمتلازمة أيكاردي-غوتييه من النوع الرابع | 2800 درهم | معتمد من هيئة الصحة بدبي
- ✓ Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited NGS Processing (Cert: INT/EGQ/2509DA/3139).
- ✓ Premium Logistics: Paid Hospital-Grade Home Collection (8 AM – 11 PM) via ISO Certified Cold-Chain and VIP Mobile Phlebotomy.
- ✓ Clinical Guidance: Telephonic Post-Test Clinical Guidance for result interpretation by expert genetic counsellors.
- ✓ Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
يُقدم هذا التحليل الجيني المتطور بأعلى معايير الدقة والسلامة المعتمدة من هيئة الصحة بدبي، مع خدمة سحب منزلي متميزة واستشارة وراثية متكاملة لضمان راحة البال والامتثال الكامل للقوانين الصحية في دولة الإمارات.
Overview
The RNASEH2A Gene Sequencing Test detects pathogenic variants in the RNASEH2A gene, confirming Aicardi-Goutières Syndrome Type 4 (AGS4) with 99.9% analytical sensitivity. يكشف تحليل تسلسل جين RNASEH2A عن الطفرات الممرضة في الجين RNASEH2A، مؤكداً متلازمة أيكاردي-غوتييه من النوع الرابع (AGS4) بحساسية تحليلية تبلغ 99.9%. This DNA test using Next-Generation Sequencing (NGS) is the gold standard for diagnosing this severe neuroinflammatory disorder in UAE patients. يُعتبر اختبار الحمض النووي هذا باستخدام التسلسل الجيني من الجيل التالي (NGS) المعيار الذهبي لتشخيص هذا الاضطراب العصبي الالتهابي الشديد لدى المرضى في الإمارات.
| Feature | Our RNASEH2A NGS Test | Whole Exome Sequencing (WES) |
|---|---|---|
| Methodology | Targeted Gene NGS (Full Gene Coverage) | Whole Exome Sequencing (All Genes) |
| Analytical Sensitivity | >99.9% for RNASEH2A | ~95% for coding regions |
| Turnaround Time | 3 – 4 Weeks | 6 – 8 Weeks |
| Cost (AED) | 2,800 | 8,000+ |
Physician Insight & Safety Protocol
“As a neurologist, I emphasize that a diagnosis of Aicardi-Goutières Syndrome Type 4 relies not only on genetic confirmation but also on clinical correlation with neuroimaging and interferon signatures. Early genetic testing via NGS empowers families to make informed decisions about treatment and supportive care. Please always interpret results in consultation with a medical geneticist.”
— Dr. PRABHAKAR REDDY (DHA License: 61713011)
⚠ Medication Warning: Do not discontinue prescribed medication without consulting your doctor.
Exclusion Criteria:
- Not suitable for patients without a clinical suspicion of Aicardi-Goutières syndrome (e.g., isolated developmental delay) or those unwilling to provide informed consent.
- If the patient has an acute infection or is on immunosuppressive therapy, discuss with ordering physician before sample collection.
Emergency Red Flags:
- Sudden neurological deterioration (seizures, loss of consciousness, severe irritability with fever) – seek emergency medical attention immediately.
- Genetic test results will not replace urgent clinical management; always contact your healthcare provider for acute changes.
Patient FAQ & Clinical Guidance
What is the RNASEH2A gene and Aicardi-Goutières Syndrome Type 4?
Snippet: The RNASEH2A NGS test identifies disease-causing variants in the RNASEH2A gene, confirming Aicardi-Goutières syndrome type 4 diagnosis.
Our comprehensive next‑generation sequencing test examines the entire RNASEH2A gene to detect pathogenic mutations linked to this rare neuroinflammatory encephalopathy. Aicardi‑Goutières syndrome type 4 typically presents in infancy with irritability, seizures, developmental regression, and characteristic brain calcifications visible on CT or MRI.
يكشف اختبار تسلسل الجين RNASEH2A عن الطفرات المسببة لمتلازمة أيكاردي-غوتييه من النوع الرابع، وهو اعتلال دماغي التهابي نادر يظهر عادةً في الرضاعة مع نوبات تشنجية وتراجع نمائي وتكلسات دماغية مميزة.
How is the test performed and what is the turnaround time?
Snippet: A simple home blood draw yields results in 3–4 weeks using Next‑Generation Sequencing technology.
A certified phlebotomist collects a single blood sample (or extracted DNA/FTA card) at your home between 8 AM and 11 PM, ensuring cold‑chain transport to our ISO‑accredited laboratory. The entire RNASEH2A gene is sequenced using NGS, with a turnaround time of 3–4 weeks. A pre‑test genetic counselling session is strongly recommended to draw a pedigree chart of affected family members.
يتم جمع عينة دم بسيطة منزلياً وتُحلل بتقنية التسلسل الجيني من الجيل التالي، وتظهر النتائج في غضون 3-4 أسابيع.
Does insurance cover this genetic in UAE?
Snippet: Many UAE insurers cover medically necessary genetic testing for Aicardi‑Goutières syndrome with prior approval; we verify directly.
Our team handles direct billing verification with all major UAE insurers. We obtain prior authorization on your behalf, ensuring compliance with Federal Decree‑Law No. 41 of 2024 and UAE PDPL. Simply send your insurance details via WhatsApp to +971 54 548 8731, and we will confirm coverage before the collection.
تغطي العديد من شركات التأمين في الإمارات الاختبارات الجينية الضرورية طبياً لمتلازمة أيكاردي-غوتييه بعد الحصول على الموافقة المسبقة؛ ونتولى التحقق مباشرةً.
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Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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