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Test Price

2,800 AED

✅ Home Collection Available

RBM10 Gene TARP Syndrome Genetic Test in UAE | 2800 AED | DHA Licensed

Executive Summary & Core Metrics

Executive Summary

  • Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited NGS Processing.
  • Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
  • Clinical Guidance: Telephonic Post-Test Clinical Guidance with a DHA-Licensed Consultant Medical Genetics Expert.
  • Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.

Test Overview & Methodology

This test sequences the entire RBM10 gene to detect pathogenic variants causing TARP syndrome (talipes equinovarus, atrial septal defect, Robin sequence, persistent left superior vena cava). The analysis uses next-generation sequencing (NGS) on the Illumina platform with paired-end reads, achieving 99.9% analytical sensitivity for single-nucleotide variants, insertions, deletions, and splice-site alterations across all coding exons and flanking intronic regions.

Feature Our Test Closest Alternative
Precision NGS with full gene sequencing, 99.9% analytical sensitivity Sanger sequencing (targeted exons only, may miss deep intronic/regulatory variants)
Methodology Next Generation Sequencing (NGS) – Illumina platform, paired-end reads Capillary sequencing; limited to known hotspots
Speed 3–4 Weeks (comprehensive report) 5–6 Weeks; often batched

Physician Insight & Safety Protocols

“I recognise that a suspected diagnosis of TARP syndrome can be overwhelming for families. This genetic test is a critical step toward accurate diagnosis and targeted multidisciplinary care. Please remember that results must be interpreted alongside clinical findings by a qualified clinical geneticist or paediatrician.” – Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA Registration ID: 9294403)

Important Advisory

Medication Precautions

Do not discontinue any prescribed medication without consulting your doctor. Genetic test results provide diagnostic guidance but do not replace ongoing clinical management or medication adjustments supervised by a physician.

Exclusion Criteria & Emergency Red Flags

This test is not suitable for patients who are acutely unstable, have severe coagulopathy uncorrected, or are unable to provide informed consent (guardian required for minors per Federal Decree-Law No. 4 of 2016 on Medical Liability).

Seek immediate emergency care if the patient develops: cyanosis unresponsive to oxygen, apnoeic episodes, severe respiratory distress, or hypoglycaemic seizures.

Patient FAQ & Clinical Guidance

1. What does the RBM10 gene TARP syndrome test detect, and how accurate is it?

This test detects pathogenic variants across the entire RBM10 gene with 99.9% diagnostic sensitivity, confirming TARP syndrome when correlated with clinical features such as talipes and cardiac anomalies. The comprehensive NGS approach captures single-nucleotide variants, small insertions and deletions, and splice-site alterations that might be missed by targeted methods.

2. Is home sample collection available, and how do I prepare my child?

Yes, our DHA-compliant VIP mobile phlebotomy team provides hospital-grade home collection across all seven emirates between 8 AM and 11 PM. No fasting is required, but a pre-test genetic counselling session is strongly recommended prior to sample collection to discuss test implications and obtain informed consent.

3. When will I receive results and who will explain them?

Results are delivered within 3–4 weeks. Your package includes a telephonic post-test guidance session with a DHA-licensed Consultant Medical Genetics specialist, who will interpret the findings, discuss implications for clinical management and family screening, and address any questions you may have.

4. Can this test detect all genetic causes of TARP syndrome?

This test is specific to the RBM10 gene, which is the only known gene associated with TARP syndrome. Full gene sequencing covers all coding exons and conserved splice sites. However, if clinical suspicion remains high after a negative result, further evaluation including chromosomal microarray or whole exome sequencing may be considered on a case-by-case basis.

UAE Regulatory & Data Privacy Adherence

Regulatory Compliance & Data Protection

This test and all associated data processing are fully compliant with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient consent, data minimisation, and secure handling protocols are strictly enforced. All clinical procedures adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability for patient safety.

Clinical & Logistical Metadata

Test Name RBM10 Gene TARP Syndrome Genetic Test
Price (AED) 2,800 AED
Turnaround Time 3–4 Weeks
Sample Type / Matrix Whole Blood (EDTA) – Peripheral Venous Blood
Methodology Used Next-Generation Sequencing (NGS) – Illumina Paired-End Platform
ICD-10-CM Code Q87.8
LOINC Code 81247-9
DHA Facility License & Laboratory Address DHA Facility License Number: 1143
Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE
Corporate Lab Branding: DNA Labs UAE

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All reports reviewed by DHA-Certified physicians