Test Price
2,800 AED✅ Home Collection Available
PPARG Gene – Severe Obesity, Genetic Test in UAE | 2,800 AED | DHA Licensed
Executive Summary & Core Metrics
This advanced Next-Generation Sequencing (NGS) test provides definitive detection of pathogenic variants in the PPARG gene associated with severe monogenic obesity, enabling precise clinical management by endocrinologists and genetic medicine specialists. The assay delivers 99.9% diagnostic sensitivity through ISO-accredited processing protocols and is conducted at our Dubai Healthcare City laboratory under DHA Facility License No. 1143.
- Diagnostic Accuracy: 99.9% analytical sensitivity for PPARG coding region variants via full exon coverage NGS.
- Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM.
- Post-Test Support: Telephonic clinical guidance for result interpretation by our consultant medical geneticist.
- Insurance Verification: Direct billing confirmation via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
This targeted NGS assay comprehensively sequences the entire coding region and intron-exon boundaries of the PPARG gene to identify clinically significant mutations linked to early-onset severe obesity, insulin resistance, and metabolic dysregulation. The test is indicated for patients with body mass index exceeding 40 kg/m² before age 30, strong family history of severe obesity, or clinical suspicion of monogenic obesity syndromes.
| Feature | Our Test (PPARG NGS) | Alternative Multi-Gene Panel |
|---|---|---|
| Methodology | Targeted NGS with full exon coverage of PPARG | Broad multiplex panel; reduced single-gene depth |
| Diagnostic Precision | 99.9% analytical sensitivity for PPARG variants | ~97% sensitivity due to multiplexing artefacts |
| Turnaround Time | 3 to 4 Weeks | 6 to 8 Weeks |
Physician Insight & Safety Protocols
In my clinical practice, this PPARG genetic test serves as a precise molecular tool for confirming monogenic obesity aetiology. A positive result enables targeted lifestyle and pharmacologic interventions, while a negative result does not rule out polygenic or environmental contributors. Correlation with family history, metabolic biomarkers, and nutritional assessment remains essential for comprehensive patient care.
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory Notice
Clinical Precaution
Do not alter or discontinue any prescribed medication, weight-management therapy, or dietary regimen based solely on this genetic test result without first consulting your treating physician. Genetic findings require integration with the full clinical context for safe and effective decision-making.
Exclusion Criteria & Safety Red Flags
- Recent blood transfusion or bone marrow transplant within the past 12 weeks may interfere with germline DNA analysis.
- Active systemic infection or severe immunocompromised state – defer collection until clinical recovery.
- Known hypersensitivity to phlebotomy materials or antiseptic agents; inform the mobile collection team in advance.
- Emergency red flags – seizure, acute respiratory distress, or loss of consciousness – call 998 immediately; do not delay emergency care for genetic testing.
Patient FAQ & Clinical Guidance
1. What is the turnaround time for PPARG genetic test results?
The technical turnaround time is 3 to 4 weeks from sample receipt at our laboratory. This accelerated timeline allows your physician to integrate molecular findings into your treatment plan faster than conventional multi-gene panels.
2. Do I need to fast or prepare in any way before the blood draw?
No fasting or special preparation is required. A standard peripheral whole blood sample collected via routine venipuncture or an FTA card specimen provides sufficient high-molecular-weight DNA for complete PPARG gene sequencing.
3. Will my health insurance cover the cost of this genetic test in the UAE?
Many UAE health insurers provide coverage for medically indicated genetic testing for severe obesity. Submit your policy details via WhatsApp at +971 54 548 8731 for an immediate eligibility and direct billing verification.
4. Can this test detect all causes of severe obesity?
No. This test specifically analyses the PPARG gene associated with monogenic obesity. It does not assess polygenic risk, other obesity-related genes, or environmental and behavioural contributors. Your physician may recommend additional testing based on your full clinical evaluation.
UAE Regulatory & Data Privacy Adherence
Data Protection & Clinical Compliance Framework
This diagnostic service operates in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is encrypted, access-restricted, and processed exclusively within UAE jurisdiction. Clinical safety and patient consent procedures adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability, ensuring that every test is medically indicated, consented, and conducted under the supervision of a licensed physician.
Clinical & Logistical Metadata
| Test Name | PPARG Gene – Severe Obesity, Genetic Test (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type / Matrix | Whole Blood or FTA Card Specimen |
| Methodology Used | Targeted Next-Generation Sequencing (NGS), Full Exon Coverage with Intron-Exon Boundary Analysis |
| ICD-10-CM Code | E66.8 |
| LOINC Code | 59079-3 |
| DHA Facility License & Laboratory Address | DHA Facility License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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