Test Price
2,800 AED✅ Home Collection Available
PLEKHG5 Gene Distal Spinal Muscular Atrophy Type 4 (DSMA4) Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين PLEKHG5 لضمور العضلات الشوكي البعيد من النوع الرابع في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary – Your Precision Diagnostic Partner
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified NGS Processing.
- Premium Logistics: VIP Mobile Phlebotomy with Hospital-Grade Home Collection (8 AM – 11 PM) & ISO Certified Cold-Chain Transport.
- Clinical Guidance: Complimentary Telephonic Post‑Test Clinical Guidance by a Genetic Counsellor.
- Insurance: Direct Billing Verification via WhatsApp: +971 54 548 8731.
فحص الجين بدقة عالية لتشخيص المرض العضلي الوراثي بدعم استشارة جينية.
Overview
The PLEKHG5 gene NGS test identifies pathogenic mutations causing distal spinal muscular atrophy type 4 (DSMA4), an autosomal recessive neuromuscular disorder characterised by progressive weakness in hands and feet, typically with adult onset. This next‑generation sequencing test delivers comprehensive analysis of all coding exons, offering definitive diagnosis for at‑risk families across the UAE.
| Feature | Our Test (NGS Full‑Gene) | Closest Alternative (Sanger Single‑Exon) |
|---|---|---|
| Methodology | Next‑Generation Sequencing (NGS) | Sanger Sequencing of one exon |
| Coverage | All coding exons & splice sites | Single exon, may miss deep intronic variants |
| Sensitivity | 99.9% (validated against reference standards) | ~85% (depends on variant location) |
| Turnaround Time | 3 – 4 weeks | 2 – 3 weeks |
| Patient Price | 2800 AED | Not directly comparable |
Physician Insight & Safety Protocol
“A confirmed PLEKHG5 mutation provides critical information for prognosis and reproductive counselling, yet all genetic results must be correlated with clinical examination and electromyography. This test is a diagnostic aid, not a standalone clinical verdict.” – Dr. PRABHAKAR REDDY, Consultant Neurologist, DHA License: 61713011.
Patient Safety Exclusion Criteria
- Recent blood transfusion (within 2 weeks) – may compromise DNA extraction purity.
- Active acute infection with high fever – reschedule after recovery.
ER Red Flags – Seek Immediate Care
- New‑onset respiratory distress or difficulty swallowing.
- Rapidly progressive limb weakness over days, not months.
Pre‑Test Requirements
A genetic counselling session is mandatory; our team will draw a detailed family pedigree chart documenting affected relatives. Please provide complete clinical history including age at onset and any previous neurological investigations. No fasting is needed. The sample options are: Whole Blood in EDTA tube, Extracted DNA, or a single drop on FTA card – our VIP mobile team handles collection conveniently.
Insurance & Billing: Direct verification via WhatsApp +971 54 548 8731.
Patient FAQ & Clinical Guidance
1. What is the purpose of the PLEKHG5 gene NGS test?
The detects mutations in the PLEKHG5 gene to confirm distal spinal muscular atrophy type 4, enabling precise prognosis and family screening. It verifies whether you carry two mutated copies, establishing the diagnosis of this autosomal recessive condition, and helps unaffected relatives understand their carrier status.
يكشف التحليل عن الطفرات في جين PLEKHG5 لتأكيد تشخيص ضمور العضلات الشوكي البعيد النوع الرابع، مما يتيح تنبؤاً دقيقاً وفحصاً عائلياً. ويؤكد وجود نسختين معطوبتين من الجين، مما يحدد التشخيص للحالة الوراثية المتنحية، ويساعد الأقارب غير المصابين على معرفة وضعهم الناقل.
2. How is the sample collected?
A simple blood draw or a drop of blood on FTA card is collected at your home by our VIP mobile phlebotomy team, with no fasting required. Our professionals use hospital‑grade aseptic technique and ensure cold‑chain transport to the laboratory immediately after collection.
يتم جمع عينة دم بسيطة أو قطرة دم على بطاقة FTA في منزلك عبر فريق التمريض المتنقل VIP، دون الحاجة إلى صيام. يستخدم فريقنا تقنية معقمة من المستوى الاستشفائي ويضمن النقل بسلسلة تبريد فورية إلى المختبر.
3. How long does it take to receive results?
Results are typically available within 3 to 4 weeks due to the comprehensive NGS analysis and expert interpretation, ensuring the highest accuracy. The extensive sequencing, bioinformatics verification, and dual‑clinician sign‑off guarantee a reliable report you can trust for life‑changing decisions.
تتوفر النتائج عادة في غضون 3 إلى 4 أسابيع بسبب التحليل الشامل بالتسلسل الجيني وتفسير الخبراء، مما يضمن أعلى دقة. إن عملية التسلسل الواسعة والتحقق المعلوماتي الحيوي واعتماد تقرير الطبيبين المزدوج يضمن تقريراً موثوقاً لقرارات مصيرية.
Accredited by:
ISO 9001:2015 Certification – Cert: INT/EGQ/2509DA/3139
Compliance: Federal Decree-Law No. 41 of 2024 (Art. 87), CDS Law 2026 (Minors), UAE PDPL.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians