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Test Price

2,800 AED

✅ Home Collection Available

NRXN1 Gene Sequencing for Pitt-Hopkins Syndrome – Genetic Test in Dubai, UAE

Executive Summary & Core Metrics

  • Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
  • Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily 8 AM – 11 PM.
  • Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.
  • Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.

Test Overview & Methodology

The NRXN1 gene sequencing test identifies pathogenic variants associated with Pitt-Hopkins syndrome, a rare genetic disorder characterized by intellectual disability, breathing abnormalities, and distinct facial features. This NGS test provides comprehensive analysis of the entire NRXN1 gene, including detection of deletions via MLPA.

Feature Our Test Closest Alternative
Precision >99.9% coverage of coding exons, 20X depth Targeted mutation panel limited
Method NGS with MLPA for deletions Sanger sequencing of selected exons
Speed 3-4 Weeks 4-6 Weeks

Physician Insight & Safety Protocols

As a Consultant Medical Genetics, I advise that this test uncovers critical genetic information affecting developmental trajectory. Families should correlate findings with clinical assessments and genetic counseling. No single lab result should stand alone; comprehensive evaluation ensures appropriate management. — Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA ID: 9294403

Advisory on Medication and Test Preparation

Important Notice

Please consult your physician before stopping any prescribed medications. This test requires no special preparation; however, inform the phlebotomist of any anticoagulant use.

Safety Exclusion Criteria & Emergency Red Flags

  • Patient must be clinically stable; active febrile illness may delay sample collection.
  • Avoid anticoagulant use within 48 hours before blood draw if possible, unless medically necessary.
  • If the patient exhibits signs of acute respiratory distress, seizures, or severe dehydration, seek immediate emergency care instead of scheduling a test.
  • This test is not for carrier screening in asymptomatic adults without confirmed family history; consult genetic counseling first.

Patient FAQ & Clinical Guidance

1. What does this test detect?

This NGS sequences the entire NRXN1 gene to identify point mutations, small deletions, or insertions that cause Pitt-Hopkins syndrome, providing a definitive genetic diagnosis.

2. How soon can I get results?

Results are typically available within 3 to 4 weeks; we provide expedited reporting for urgent clinical cases upon request.

3. Is home sample collection safe?

Yes, our DHA-licensed phlebotomists use ISO-certified cold-chain transport, ensuring sample integrity from your doorstep to our CAP-accredited lab.

UAE Regulatory & Data Privacy Adherence

Compliant with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Additionally adheres to Federal Decree-Law No. 4 of 2016 on Medical Liability.

DHA License No.: 1143 | Laboratory Address: Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE

Support: WhatsApp & Phone +971 54 548 8731 | 8 AM – 11 PM daily

Clinical & Logistical Metadata

Test Name NRXN1 Gene Sequencing for Pitt-Hopkins Syndrome
Price (AED) 2,800 AED
Turnaround Time 3 to 4 Weeks
Sample Type / Matrix Peripheral Whole Blood (Home Collection Available via VIP Mobile Phlebotomy)
Methodology Used Next-Generation Sequencing (NGS) with MLPA deletion analysis
ICD-10-CM Code Q87.0
LOINC Code 21797-6
DHA Facility License & Laboratory Address License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE

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