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Results: 3โ€“4 Weeks Sample: Peripheral Whole Blood (EDTA)

Test Price

2,800 AED

โœ… Home Collection Available

๐Ÿ“‹ Results in 3โ€“4 Weeks

NODAL Gene Heterotaxy Visceral Type 5 Genetic Test in UAE | 2800 AED | DHA Licensed

Executive Summary & Core Metrics

  • โœ“99.9% Diagnostic Sensitivity โ€“ ISO-accredited NGS laboratory processing.
  • โœ“VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection โ€“ Available daily from 8 AM to 11 PM.
  • โœ“Post-Test Clinical Guidance โ€“ Telephonic consultation with a DHA-licensed Consultant Medical Genetics to interpret results.
  • โœ“Direct Insurance Billing โ€“ Verification via WhatsApp +971 54 548 8731.

Test Overview & Methodology

This NGS-based genetic test sequences the entire NODAL gene to detect mutations causing visceral heterotaxy type 5, a serious laterality defect affecting heart, spleen, and organ positioning. Our test utilizes the latest Illumina platform with 100X coverage and full gene analysis, while common alternatives rely on limited targeted panels with lower resolution.

Feature Our Test Closest Alternative
Precision 99.9% analytical sensitivity ~95%
Method NGS Full Gene Sequencing (Illumina) Sanger or Panel Sequencing
Speed 3โ€“4 Weeks 6โ€“8 Weeks

Physician Insight & Safety Protocols

โ€œAs a Consultant Medical Genetics, I emphasize that a NODAL variant must be correlated with clinical findings and family history. This test provides a molecular diagnosis that guides surgical planning and genetic counselling. Results should never be used as a sole basis for altering any prescribed therapy.โ€

โ€” Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403

Medication Advisory

Do not discontinue or modify prescribed medication based solely on genetic test results. Always consult your treating physician before making any changes to ongoing therapy.

Exclusion Criteria & Emergency Red Flags

  • Active febrile illness or acute infection (postpone collection).
  • Known bleeding diathesis or anticoagulant therapy (requires specialized phlebotomy).
  • If the proband develops severe cyanosis, respiratory distress, or cardiac arrhythmia, seek emergency care immediately โ€“ do not wait for test results.
  • This test is not validated for prenatal diagnosis using amniocytes without prior authorization.

Patient FAQ & Clinical Guidance

1. Who should undergo NODAL gene heterotaxy testing?

Any infant or child with situs ambiguus, complex congenital heart disease, or asplenia suspected to have visceral heterotaxy. Early molecular diagnosis can significantly improve surgical planning and family counselling.

2. Can this test be used for prenatal diagnosis?

Standard testing is validated on postnatal blood samples. Prenatal samples (amniotic fluid or CVS) require specific pre-authorization and genetic counselling before collection.

3. How is the sample collected for infants or children?

A pediatric phlebotomist performs a minimally traumatic heel stick or venipuncture during the scheduled home collection visit. All procedures follow strict infection control protocols.

UAE Regulatory & Data Privacy Adherence

Regulatory Compliance & Data Protection

  • All genetic data is processed in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL).
  • Health information handling adheres to Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
  • Clinical safety and patient consent are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability.
  • Testing is performed at a DHA-licensed facility (License No. 1143) and the laboratory follows ISO 9001:2015 standards (Cert: INT/EGQ/2509DA/3139).

Clinical & Logistical Metadata

Test Name NODAL Gene Heterotaxy Visceral Type 5 Genetic Test (NGS)
Price (AED) 2,800 AED
Turnaround Time 3โ€“4 Weeks
Sample Type / Matrix Peripheral Whole Blood (EDTA)
Methodology Used Next-Generation Sequencing (Illumina) โ€“ Full Gene Sequencing
ICD-10-CM Code Q89.3
LOINC Code 82543-0
DHA Facility License & Laboratory Address DNA Labs UAE, Facility License No. 1143, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE

ุฏุนู… ุซู†ุงุฆูŠ ุงู„ู„ุบุฉ ู…ุชุงุญ

ุงู„ุชุญู‚ู‚ ู…ู† ุงู„ุชุบุทูŠุฉ ุงู„ุชุฃู…ูŠู†ูŠุฉ

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ุชูˆู‚ู ุนู† ุงู„ุชุฎู…ูŠู†. ุฃุฑุณู„ ุตูˆุฑุฉ ู…ู† ุจุทุงู‚ุฉ ุงู„ุชุฃู…ูŠู† ูˆูˆุตูุฉ ุงู„ุทุจูŠุจ ุฅู„ู‰ ูุฑูŠู‚ ุงู„ุชุญู‚ู‚ ุงู„ู…ุนุชู…ุฏ ู…ู† ู‡ูŠุฆุฉ ุงู„ุตุญุฉ ุจุฏุจูŠ ุนุจุฑ ุงู„ูˆุงุชุณุงุจ. ุงุญุตู„ ุนู„ู‰ ุชุญุฏูŠุซ ุงู„ุญุงู„ุฉ ููŠ ุฏู‚ุงุฆู‚.

โœ… DHA Certified โœ… ISO 15189 โœ… HIPAA Compliant

Available in Arabic, English, Hindi & Urdu

Preparation Required

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Medically Reviewed by Dr. Lina Osama Zaki Quteineh

All content reviewed by qualified professionals for accuracy.

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ISMS 27001:2022

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ISO Accredited

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HIPAA

All reports reviewed by DHA-Certified physicians