Test Price
2,800 AED✅ Home Collection Available
NBN Gene (Nijmegen Breakage Syndrome) NGS Genetic Test in Dubai | 2800 AED | DNA Labs UAE
Executive Summary & Core Metrics
Comprehensive Genetic Analysis at Your Doorstep
- Diagnostic Accuracy: 99.9% sensitivity via Next-Generation Sequencing in an ISO 9001:2015 accredited laboratory.
- VIP Mobile Phlebotomy: Temperature-controlled cold-chain home collection available from 8 AM to 11 PM across all Emirates.
- Post-Test Guidance: Telephonic clinical insight session with a Board-Certified Medical Geneticist for result interpretation.
- Insurance Verification: Real-time coverage confirmation via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The NBN Gene NGS Test identifies pathogenic variants in the NBN gene linked to Nijmegen breakage syndrome (NBS), a rare autosomal recessive disorder characterized by microcephaly, immunodeficiency, and elevated cancer risk. This comprehensive sequencing test covers the entire coding region and splice sites to enable precise diagnosis, carrier screening, and personalized management.
| Feature | Our NBN NGS Test | Closest Alternative (Sanger Panels) |
|---|---|---|
| Methodology | Next-Generation Sequencing (NGS) – full gene coverage, high sensitivity for mosaic and deep intronic variants | Sanger sequencing of select exons; may miss deep intronic variants or low-level mosaicism |
| Turnaround Time | 14–21 business days with ISO-certified cold-chain logistics | 4–6 weeks, no integrated home collection timeline |
| Pre- & Post-Test Support | Mandatory pre-test genetic counseling session + post-result telephonic clinical guidance | Often limited to reporting; no structured counseling framework |
| Price | 2800 AED | Average 3200–3500 AED |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh (DHA Registration ID: 9294403), Consultant Medical Genetics, shares: “A positive NBN variant does not guarantee disease development; clinical correlation with family history and immunological assessments is essential. Early diagnosis through this test allows proactive surveillance for malignancies and infections, empowering families with knowledge and preventive strategies. Please consult your specialist before making any medical decisions based on your result.”
Advisory & Safety Considerations
⚠️ Medication Caution
Do not discontinue or alter any prescribed medication without explicit guidance from your treating physician. This test result may inform future therapeutic decisions but should not trigger abrupt changes to existing regimens.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Recent blood transfusion or bone marrow transplant (within the last 2 weeks); active severe infection or unstable clinical condition; non-consenting individuals per UAE law.
- Emergency Red Flags: Sudden high fever, severe infection, or signs of malignancy (unexplained lumps, easy bruising, prolonged bleeding) – seek immediate medical attention irrespective of test scheduling.
Patient FAQ & Clinical Guidance
1. What does the NBN gene test diagnose?
The NBN gene test diagnoses Nijmegen breakage syndrome, a rare genetic disorder causing microcephaly, immunodeficiency, and high cancer risk. It detects pathogenic mutations in the NBN gene that can confirm clinical suspicion, guide early cancer surveillance, and enable family planning decisions.
2. How is the sample collected for this test in the UAE?
Our DHA-licensed phlebotomist collects a small blood sample from the comfort of your home within 24 hours. We use whole blood, extracted DNA, or a single drop on an FTA card, transported under ISO-certified cold-chain conditions to guarantee DNA integrity. VIP Mobile Phlebotomy is available daily from 8 AM to 11 PM across all Emirates.
3. Is genetic counseling required before taking the NBN test?
Yes, a mandatory pre-test genetic counseling session is required to explain the implications, family risks, and the informed consent process. This session, conducted by a qualified genetic counselor, includes a detailed pedigree analysis and ensures compliance with UAE data protection laws. The session is included in the test package with no additional cost.
4. What is the turnaround time for this test?
The standard turnaround time is 14 to 21 business days from the sample receipt at the laboratory. This timeline accommodates rigorous quality control measures, including dual bioinformatics analysis and manual variant curation, to ensure 99.9% diagnostic accuracy.
UAE Regulatory & Data Privacy Adherence
All procedures and data handling comply with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Genetic data is encrypted, anonymized, and processed exclusively within our ISO 9001:2015 certified facility (Cert: INT/EGQ/2509DA/3139). Clinical testing safety and patient consent operate under the framework of Federal Decree-Law No. 4 of 2016 on Medical Liability. For minors, guardian consent and supervision are strictly enforced. Your results are confidential and accessible only through your secure patient portal with two-factor authentication.
Clinical & Logistical Metadata
| Test Name | NBN Gene Full Sequencing (NGS) – Nijmegen Breakage Syndrome |
| Price (AED) | 2,800 AED |
| Turnaround Time | 14–21 Business Days |
| Sample Type / Matrix | Whole Blood (EDTA), Extracted DNA, or FTA Card Dried Blood Spot |
| Methodology Used | Next-Generation Sequencing (NGS) – Illumina Platform, Full Gene & Splice Sites |
| ICD-10-CM Code | Q87.8 (Other specified congenital malformation syndromes) |
| LOINC Code | 69079-5 (DNA sequencing panel for hereditary disorder) |
| DHA Facility License & Laboratory Address | License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians