Test Price
2,800 AED✅ Home Collection Available
MYBPC1 Gene Sequencing for Distal Arthrogryposis Type 1B (NGS) Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل تسلسل جين MYBPC1 لمرض التقلص المفصلي البعيد من النوع 1B في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Relevant Specialists: Clinical Geneticist, Pediatric Orthopedic Surgeon, Neonatologist.
Executive Summary / ملخص تنفيذي
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection and VIP Mobile Phlebotomy.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
الفحص الجيني الشامل يحدد الطفرات المسببة لحالة التقلص المفصلي البعيد من النوع 1B، مما يمكن الأطباء من تقديم تشخيص دقيق واستشارة وراثية متكاملة.
Overview
This Next-Generation Sequencing (NGS) test analyzes the entire coding region of the MYBPC1 gene to detect pathogenic variants causing distal arthrogryposis type 1B, a rare congenital contracture disorder. الفحص الجيني الشامل يحدد الطفرات المسببة لحالة التقلص المفصلي البعيد من النوع 1B، مما يمكن الأطباء من تقديم تشخيص دقيق واستشارة وراثية متكاملة.
Technical Specifications
- Methodology: Next-Generation Sequencing (NGS), full gene coding region ±10 bp exon/intron boundaries.
- LOINC: 51969-3 (Genetic disease sequence variant analysis).
- 2026 ICD-10-CM Codes: Q68.8 (Other specified congenital musculoskeletal deformities), Z13.79 (Encounter for screening for genetic and chromosomal anomalies), Z15.89 (Genetic susceptibility to other disease).
- Sample Types: Whole Blood (EDTA), Extracted DNA, or one drop blood on FTA Card.
- Turnaround Time: 3 to 4 Weeks.
Test Comparison: Our NGS vs. Closest Alternative
| Feature | Our Test (NGS) | Sanger Sequencing (Alternative) |
|---|---|---|
| Technology | Next-Generation Sequencing (NGS) | Sanger sequencing |
| Coverage | Full MYBPC1 gene (>99% bases covered at >20x) | Targeted coding exons only |
| Sensitivity | 99.9% for SNVs, small indels, and copy number variants* | ~99% for point mutations, limited large deletion detection |
| Turnaround Time | 3–4 Weeks | 4–6 Weeks |
| Price | 2800 AED | Variable, often unavailable |
*CNV detection via NGS with complementary MLPA confirmation when needed.
Physician Insight & Safety Protocol
“As a clinical geneticist, I emphasize that this test must be interpreted within the full clinical and family history context; a positive result confirms the diagnosis but does not predict severity. Pre- and post-test genetic counseling are essential for informed decision-making. Do not discontinue prescribed medications or physical therapy without consulting your doctor.”
— Dr. PRABHAKAR REDDY, DHA License No. 61713011
Safety Alert & Exclusion Criteria
- Medication Warning: Do not discontinue prescribed medication without consulting your doctor.
- If you have had a blood transfusion within the last 2 weeks, please inform our team to avoid sample rejection.
- ER Red Flags: Seek emergency care immediately if you or your child develop difficulty breathing, severe worsening of joint contractures, or feeding difficulties prior to or after test.
- This genetic test is not intended as a stand-alone diagnostic tool; clinical correlation is mandatory.
UAE Regulatory Compliance & Accreditation
- Licensed by DHA, Facility License No. 9834453, per Federal Decree-Law No. 41 of 2024 (Art. 87).
- Compliant with CDS Law 2026 for minors’ genetic testing consent requirements.
- UAE PDPL-compliant handling ensures genetic data privacy and confidentiality.
- ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139) for quality management.
- Sample collection via ISO certified cold-chain logistics; Home service available 8 AM – 11 PM daily.
Patient FAQ & Clinical Guidance
1. What does the MYBPC1 gene test detect and who should consider it?
Snippet: The MYBPC1 gene test detects pathogenic variants linked to distal arthrogryposis type 1B, indicated for individuals with congenital distal joint contractures.
This test is indicated for newborns, children, or adults presenting with bilateral distal joint contractures, clenched fists, clubfoot, and overlapping fingers, without major proximal involvement. A positive result confirms a molecular diagnosis of distal arthrogryposis type 1B (DA1B), enabling accurate genetic counseling for family planning and prognosis. Testing can also be offered to at-risk family members. Our laboratory requires a physician referral and pre-test genetic counseling to draw a detailed pedigree before sample submission.
يكشف اختبار جين MYBPC1 عن الطفرات المسببة لحالة التقلص المفصلي البعيد من النوع 1B، ويُوصى به للأفراد الذين يعانون من تقلصات مفصلية خلقية في الأطراف. يُطلب هذا الفحص بعد استشارة طبيب مختص في الوراثة السريرية وجلسة استشارة وراثية لرسم شجرة العائلة.
2. How is the test performed and what is the turnaround time?
Snippet: A blood sample or DNA is collected via a painless home visit, and results are delivered within 3-4 weeks.
We offer VIP mobile phlebotomy service across the UAE, 8 AM to 11 PM. A trained nurse collects a small blood sample (or a finger-prick for FTA card) from the comfort of your home. Samples are transported in ISO-certified cold-chain containers to our DHA-licensed laboratory. Extracted DNA or stored DNA can also be submitted. The NGS process takes 3–4 weeks; the final report is reviewed by a clinical geneticist and includes variant classification according to ACMG guidelines. You will receive a secure electronic report and an optional telephonic consultation to discuss findings.
يتم سحب عينة دم بسيطة من خلال زيارة منزلية مريحة، وتظهر النتائج خلال 3-4 أسابيع. نستخدم سلسلة تبريد معتمدة لنقل العينة إلى المختبر، حيث يتم إجراء تسلسل الجيل التالي (NGS) وتحليلها. يتضمن التقرير الطبي تصنيف الطفرة واستشارة هاتفية اختيارية.
3. Is this test covered by UAE insurance and is genetic counseling included?
Snippet: We offer direct insurance billing verification and include a mandatory pre- and post-test genetic counseling session.
We accept most major UAE health insurance plans. You can send your insurance card via WhatsApp to +971 54 548 8731 for instant verification of coverage. The test price of 2800 AED may be fully or partially covered depending on your policy’s genetic testing benefits. All tests require a pre-test genetic counseling session (included) to explain the test’s implications, obtain informed consent, and draw a pedigree. A post- counseling session to interpret results is also provided at no extra charge. We ensure compliance with CDS Law 2026 on minors’ consent, requiring parental authorization.
نوفر خدمة التحقق المباشر من تغطية التأمين، ونشمل جلسة استشارة وراثية إلزامية قبل وبعد الفحص. أرسل صورة بطاقة التأمين عبر واتساب للتحقق الفوري. سعر الفحص 2800 درهم، وقد يغطيه التأمين كلياً أو جزئياً. جميع الاختبارات تلتزم بقانون CDS 2026 بشأن موافقة القاصرين.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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ISMS 27001:2022
ISO Accredited
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All reports reviewed by DHA-Certified physicians