Test Price
2,800 AEDโ Home Collection Available
MASTL Gene Thrombocytopenia Type 2 Genetic Test in UAE | 2,800 AED | DHA Licensed & ISO Certified
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139) Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (8 AM - 11 PM daily).
- Clinical Guidance: Post-test Telephonic Clinical Guidance with a DHA-licensed Consultant Medical Genetics.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731. We handle pre-approvals.
Pricing & Turnaround
- Price: 2,800 AED (all-inclusive, no hidden fees)
- Turnaround Time: 3โ4 weeks
- Sample Type: Whole blood (EDTA), extracted DNA, or FTA card
- Consultation: Included post-test counseling
Test Overview & Methodology
The MASTL Gene Thrombocytopenia Type 2 Genetic Test precisely detects pathogenic variants in the MASTL gene, responsible for an autosomal recessive giant platelet disorder with thrombocytopenia. This advanced genomic analysis using Next Generation Sequencing (NGS) provides 100% coverage of all coding regions and splice sites, enabling accurate diagnosis, family screening, and personalized management. It differentiates inherited thrombocytopenia from immune or acquired forms, avoiding unnecessary invasive procedures and misdiagnosis.
Why This Test? โ Comparative Advantage
| Parameter | Our Test (MASTL NGS Targeted Gene) | Whole Exome Sequencing (WES) |
|---|---|---|
| Methodology | Next Generation Sequencing (NGS) with 100% coverage of MASTL coding regions | Genome-wide exome capture, less focused depth |
| Diagnostic Yield for Thrombocytopenia | >99% sensitivity for known pathogenic/likely pathogenic variants | ~85% (misses deep intronic variants, may have incidental findings) |
| Turnaround Time | 3โ4 Weeks | 6โ12 Weeks |
| Cost (AED) | 2,800 | 3,500โ6,000 |
| Incidental Findings | None; gene-specific, reducing anxiety | Potential additional unsolicited results requiring more counseling |
Physician Insight & Safety Protocols
โA positive MASTL variant does not always predict bleeding severity; clinical correlation is vital. I strongly recommend discussing results with your hematologist before making any treatment changes. This test is a powerful tool, but it complements, not replaces, comprehensive clinical evaluation.โ
โ Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403
Advisory: Pre-Test Genetic Counseling & Medication Precautions
โ ๏ธ Do not discontinue prescribed medication without consulting your doctor. Genetic results do not justify abrupt cessation of anticoagulants or antiplatelet therapy.
A detailed clinical history and a genetic counselling session are mandatory to construct a pedigree chart of family members affected with MASTL-related thrombocytopenia. Informed consent must be obtained prior to sample collection, in accordance with Federal Decree-Law No. 4 of 2016 on Medical Liability.
Exclusion Criteria & Emergency Red Flags
Exclusion Criteria
- Unwillingness to undergo compulsory genetic counselling.
- Patients under 18 without legal guardian consent.
- Recent blood transfusion (<2 weeks) may compromise germline DNA purity.
- Acute bleeding episode requiring immediate emergency intervention.
Seek Emergency Care If
- Sudden appearance of extensive bruising, petechiae, or mucosal bleeding.
- Signs of intracranial haemorrhage: severe headache, vomiting, altered consciousness.
- Heavy, uncontrolled epistaxis or gastrointestinal bleeding.
These conditions require stabilization before testing. Our team can guide you.
Patient FAQ & Clinical Guidance
1. What is the MASTL gene test and why is it performed?
Answer: The MASTL gene NGS test identifies pathogenic variants causing autosomal recessive thrombocytopenia type 2, aiding precise diagnosis and treatment planning. This test differentiates inherited thrombocytopenia from immune or acquired forms, enabling targeted monitoring and family screening.
2. How should I prepare for the sample collection?
Answer: No fasting is required; ensure you have attended a genetic counselling session and signed informed consent prior to collection. Our mobile team collects blood or a finger-prick FTA card; cold-chain ensures DNA stability.
3. What do my results mean and what is the next step?
Answer: A โpathogenic variant detectedโ result confirms the diagnosis, guiding personalized management and screening of at-risk relatives. Our post-test telephonic consultation with a consultant medical geneticist will explain the implications and recommend further actions.
UAE Regulatory & Data Privacy Adherence
Your Data, Our Commitment
We strictly comply with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 concerning the use of information and communication technology in health fields. All genetic data is encrypted, access-controlled, and processed under DHA oversight. Patient consent is obtained and managed per Federal Decree-Law No. 4 of 2016 on Medical Liability. Our laboratory holds DHA Facility License 1143 and is ISO 9001:2015 certified.
Clinical & Logistical Metadata
| Test Name | MASTL Gene Thrombocytopenia Type 2 Genetic Test (NGS Targeted Sequencing) |
| Price (AED) | 2,800 |
| Turnaround Time | 21โ28 Days (3โ4 Weeks) |
| Sample Type / Matrix | Whole Blood (EDTA), Extracted DNA, or FTA Card |
| Methodology Used | Next Generation Sequencing (NGS) โ Targeted Gene Sequencing with 100% coding region coverage |
| ICD-10-CM Code | D69.4 (Other primary thrombocytopenia) |
| LOINC Code | 90556-0 (MASTL gene mutation analysis in Blood or Tissue by Sequencing) |
| DHA Facility License & Address | License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
Secure Your Precision Diagnosis Today
Book a home collection or schedule a tele-consultation. WhatsApp us for instant insurance verification.
WhatsApp +971 54 548 8731ยฉ 2025 DNA Labs UAE. Licensed by DHA/MOHAP (Facility License: 1143). All tests comply with UAE PDPL and Federal Law No. 2 of 2019. ISO 9001:2015 Certified. Not for emergency use.
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