Test Price
2,800 AEDโ Home Collection Available
MAGT1 Gene Immunodeficiency, X-Linked, with Magnesium Defect, Epstein-Barr Virus Infection and Neoplasia Genetic Test in UAE | 2800 AED
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 accredited processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This test sequences the entire MAGT1 gene using Next-Generation Sequencing (NGS) to diagnose X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection, and neoplasia, offering definitive molecular confirmation for patients with clinical suspicion. It provides actionable insights for targeted management and familial risk assessment.
| Feature | Our Test (Precision / Method / Speed) | Closest Alternative |
|---|---|---|
| Analytical Sensitivity | 99.9% (Validation-confirmed) | Variable, often 95โ98% |
| Methodology | NGS Full Gene Sequencing | Sanger Sequencing (limited coverage) |
| Turnaround Time | 3 to 4 Weeks | 6 to 8 Weeks |
| Accreditation | ISO 9001:2015 & DHA Licensed | Not uniformly specified |
Physician Insight & Safety Protocols
โGenetic testing for MAGT1 deficiency requires careful interpretation within the full clinical picture. A positive variant confirms the diagnosis but does not predict disease severity; multidisciplinary management involving immunology, oncology, and nephrology is essential for optimal outcomes. Always discuss results with a qualified genetic counselor before making any therapeutic decisions.โ
โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Safety and Advisory Information
- Exclusion Criteria: Recent blood transfusion (<2 weeks), allogeneic hematopoietic stem cell transplant within 6 months, use of leukoreduced blood products may compromise germline DNA quality.
- Emergency Red Flags โ Seek immediate care if: Acute EBV-related hemophagocytic lymphohistiocytosis symptoms (high fever, cytopenias, splenomegaly), neurological signs suggestive of CNS lymphoma, or severe hypomagnesemia (magnesium <0.5 mmol/L).
Patient FAQ & Clinical Guidance
1. What is the MAGT1 gene and why is it tested?
MAGT1 gene testing detects mutations that impair magnesium transport in immune cells, leading to X-linked immunodeficiency with EBV-driven cancers and severe infections. This NGS-based assay provides a definitive molecular diagnosis for patients presenting with recurrent infections, hypomagnesemia, and EBV-associated lymphoproliferative disorders, guiding specialists toward targeted immunomodulatory and magnesium supplementation strategies.
2. How should I prepare for the MAGT1 genetic test?
No fasting or medication changes are required before sample collection; however, a pre-genetic counselling session is mandatory to review family history. Our DHA-certified counsellors will construct a detailed pedigree chart to identify affected relatives and explain the X-linked inheritance pattern. Simply provide a blood sample or a painless one-drop blood spot on an FTA card; we handle all cold-chain logistics.
3. How soon will I receive my MAGT1 NGS results and what support follows?
Results are delivered within 3 to 4 weeks, and you receive a complimentary telephonic clinical guidance session with our senior consultant to interpret the findings. The report includes the detected variantโs pathogenicity classification according to ACMG guidelines, its correlation with magnesium defect and EBV-related neoplasia risk, and personalized recommendations for follow-up with nephrologists, immunologists, and oncologists. Insurance billing and direct scheduling are streamlined via WhatsApp.
UAE Regulatory & Data Privacy Adherence
This test is performed in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability. DNA Labs UAE is ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139) and holds DHA Facility License number 1143.
Clinical & Logistical Metadata
| Test Name | MAGT1 Gene Immunodeficiency, X-Linked, with Magnesium Defect, Epstein-Barr Virus Infection and Neoplasia Genetic Test |
| Price (AED) | 2,800 |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood (EDTA) or Dried Blood Spot (FTA Card) |
| Methodology Used | Next-Generation Sequencing (NGS) โ Full Gene Sequencing |
| ICD-10-CM Code | D81.8 (Other combined immunodeficiencies) |
| LOINC Code | 61330-7 (MAGT1 gene mutation analysis in Blood or Tissue by Molecular genetics method) |
| DHA Facility License & Laboratory Address | License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE โ DNA Labs UAE |
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