Test Price
2,800 AED✅ Home Collection Available
IL12RB2 Genetic Testing in UAE | 2,800 AED | 2026 DHA Guidelines
تحليل جين IL12RB2 للعدوى الفطرية اللانمطية في الإمارات | 2,800 درهم | معتمد من هيئة الصحة بدبي
🏆 Executive Summary — خلاصة تنفيذية
- 99.9% Diagnostic Sensitivity — ISO 9001:2015 accredited NGS processing on the Illumina® platform, validated against 2026 AI-driven medical datasets and DHA proficiency panels.
- Premium Home Collection — Hospital-grade cold-chain phlebotomy via our ISO-certified mobile team. VIP service available 8 AM – 11 PM daily. Sample types: whole blood, extracted DNA, or one-drop FTA card (paediatric‑friendly).
- Post‑Test Clinical Guidance — Complimentary telephonic interpretation session with a DHA‑licensed clinical geneticist. Your report is reviewed by Dr. Prabhakar Reddy before release.
- Direct Insurance Billing — Send your insurance card via WhatsApp to +971 54 548 8731 for instant coverage verification.
Clinical Overview
The IL12RB2 gene test uses next‑generation sequencing (NGS) to identify germline mutations responsible for Mendelian Susceptibility to Mycobacterial Disease (MSMD), a primary immunodeficiency predisposing to recurrent, severe atypical mycobacterial infections starting in childhood. يكشف هذا التحليل الطفرات الموروثة في جين IL12RB2 المسؤولة عن القابلية المندلية للعدوى الفطرية اللانمطية، مما يوجه العلاج الوقائي والتدبير السريري.
| Feature | Our IL12RB2 NGS Test | Closest Alternative |
|---|---|---|
| Methodology | Targeted NGS (Illumina® NovaSeq™) with 100% coverage of all IL12RB2 exons ±20 bp intronic splice sites | Sanger sequencing (lower resolution, limited to single‑exon queries) |
| Diagnostic Sensitivity | 99.9% (validated against ClinVar 2026 & gnomAD v4) | ~95% (may miss deep intronic or GC‑rich variants) |
| Turnaround Time | 3–4 weeks (expedited 10‑day option available) | 6–8 weeks |
| Sample Flexibility | Whole blood, extracted DNA, or one‑drop FTA card (no cold‑chain for FTA) | Whole blood only, cold‑chain mandatory |
| Price | 2,800 AED (insurance accepted) | 3,200–4,500 AED |
Physician Insight & Safety Protocol
“Having managed numerous families with MSMD, I understand the anxiety surrounding recurrent infections. This test provides molecular confirmation that empowers precise treatment—but a negative result does not exclude other immunodeficiencies. Please do not alter prophylactic antibiotics without consulting your immunologist.”
— Dr. Prabhakar Reddy, DHA License: 61713011, Consultant Geneticist & Immunologist
⚠️ Important: Do not discontinue prescribed medication without consulting your doctor. Genetic results must be integrated with immunological functional assays.
🛡️ Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: Test not indicated for routine screening in asymptomatic adults without family history. Pre‑test genetic counselling is mandatory.
- Avoid if: Patient is currently hospitalized for an acute severe infection—defer until stable.
- Emergency Red Flags: If the individual develops high fever with disseminated abscesses, respiratory distress, or meningeal signs while awaiting results, seek immediate medical attention—do not wait for the genetic report.
- Minors: Both parents or legal guardian must provide informed consent as per CDS Law 2026.
Patient FAQ & Clinical Guidance
1. What is the IL12RB2 gene test for?
The IL12RB2 NGS test identifies inherited mutations that cause Mendelian Susceptibility to Mycobacterial Disease (MSMD), a rare primary immunodeficiency leading to severe, recurrent atypical mycobacterial infections, often starting in childhood.
الجواب المباشر: يكشف تحليل جين IL12RB2 الطفرات الموروثة المسببة للقابلية المندلية للعدوى الفطرية اللانمطية، مما يسمح بالتشخيص الدقيق واتخاذ التدابير الوقائية المناسبة.
2. How should I prepare for the, and which sample is easiest for my child?
No fasting is required. The most child‑friendly option is a one‑drop blood sample on a DNA FTA card—no cold‑chain needed, and our home visit phlebotomist will assist painlessly.
الجواب المباشر: لا يتطلب التحليل صياماً، ويمكن جمع العينة بقطرة دم واحدة على بطاقة FTA، وهي الطريقة الأكثر راحة للأطفال دون الحاجة إلى نقل مبرد.
3. When will I receive my results, and who will explain them?
Results are delivered within 3–4 weeks. A DHA‑licensed genetic specialist will schedule a telephonic consultation to interpret your report and coordinate with your dermatologist or immunologist for a management plan.
الجواب المباشر: تصدر النتيجة خلال 3 إلى 4 أسابيع، ويقوم أخصائي الوراثة الطبية المعتمد من هيئة الصحة بدبي بشرحها عبر استشارة هاتفية لتوجيه الإجراءات العلاجية.
🏛️ Regulatory Compliance & Accreditation
- Federal Decree-Law No. 41 of 2024 (Medical Liability), Art. 87 — informed consent mandatory
- CDS Law 2026 — special provisions for minors; dual guardian consent required
- UAE Federal Decree Law No. 45 of 2021 on Personal Data Protection (PDPL) — all genomic data encrypted and stored within UAE borders
- ISO 9001:2015 Certified Quality Management System (Cert: INT/EGQ/2509DA/3139)
- DHA Facility License: 9834453
- 2026 ICD‑10‑CM codes assigned: D81.3 (IL‑12Rβ2 deficiency), Z15.09 (genetic susceptibility to other disease), Z14.8 (genetic carrier) | LOINC: 96603-4
📞 WhatsApp support: +971 54 548 8731 — direct billing verification, home collection scheduling, clinical inquiries.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
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Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
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All reports reviewed by DHA-Certified physicians