Test Price
2,800 AED✅ Home Collection Available
IARS2 Gene Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين IARS2 (متلازمة متعددة الأجهزة) في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
الملخص التنفيذي
- دقة تشخيصية 99.9% عبر تحليل معتمد من ISO 9001:2015 وتقنية التسلسل الجيني (NGS) المتطورة.
- خدمة سحب الدم المنزلي بنظام التبريد المعتمد (Home Collection) مع فريق تمريض متنقل، من 8 صباحاً حتى 11 مساءً.
- استشارة سريرية هاتفية بعد النتائج لتفسير التقرير الطبي وتوجيه الخطوات القادمة.
- التحقق من تغطية التأمين الصحي مباشرة عبر واتساب: +971 54 548 8731
Overview
The IARS2 Gene Genetic Test analyzes the IARS2 gene for pathogenic variants linked to a multisystemic syndrome including cataracts, growth hormone deficiency, sensorineural hearing loss, sensory neuropathy, and skeletal dysplasia. This NGS-based test offers comprehensive sequencing at 2800 AED with a 3–4 week turnaround, available for patients of all ages in the UAE, complete with DHA-compliant home sample collection.
يُحلل اختبار جين IARS2 الجيني طفرات الجين المرتبطة بمتلازمة متعددة الأجهزة تشمل الكتاركت ونقص هرمون النمو وفقدان السمع الحسي العصبي واعتلال الأعصاب وخلل التنسج العظمي. سعر الفحص 2800 درهم مع توصيل النتائج خلال 3–4 أسابيع، ويشمل جمع العينة منزليًا بمعايير هيئة الصحة بدبي.
| Feature | Our Test: IARS2 NGS | Closest Alternative: Whole Exome Sequencing |
|---|---|---|
| Precision | Near-100% coverage of IARS2 coding region + splice sites + CNV analysis | Broad analysis; lower coverage uniformity per gene |
| Methodology | Targeted NGS with clinically validated bioinformatics pipeline | Exome-wide NGS; higher incidental findings |
| Speed | 3–4 weeks | 6–8 weeks typical |
Physician Insight & Safety Protocol
“As a clinical geneticist, I emphasize that this test must be interpreted alongside a full clinical evaluation and detailed family history. A positive result confirms a genetic aetiology but does not quantify disease severity; conversely, a negative result does not exclude other genetic or acquired causes. Please use the post‑test telephonic guidance to understand implications for management and family planning.”
— Dr. Prabhakar Reddy, DHA License No. 61713011
⚠ Important Medication Warning
Do not discontinue or adjust prescribed medication without consulting your treating physician. Genetic test results are complementary and do not replace clinical judgement.
Exclusion Criteria & ER Red Flags
- Minors: Testing of individuals under 18 years requires informed parental consent and mandatory genetic counselling as per UAE Child Digital Safety (CDS) Law 2026.
- Acute Illness: Postpone sample collection if you have a current febrile illness or received a blood transfusion within the last 4 weeks.
- Pregnancy: Pregnant women must consult a specialist due to potential incidental findings.
- Seek Emergency Care Immediately If: You experience sudden vision loss, acute severe hearing loss, or new neurological deficits (e.g., numbness, weakness). These may indicate unrelated acute conditions requiring urgent management.
Patient FAQ & Clinical Guidance
What is the IARS2 gene and what conditions does it cause?
ما هو جين IARS2 وما الحالات التي يسببها؟
IARS2 pathogenic variants cause a multisystem syndrome involving cataracts, growth hormone deficiency, and sensorineural hearing loss. The IARS2 gene encodes mitochondrial isoleucyl‑tRNA synthetase; mutations disrupt mitochondrial protein synthesis, leading to the characteristic phenotype of congenital cataracts, postnatal growth failure, progressive sensorineural hearing loss, peripheral sensory neuropathy, and skeletal dysplasia. جين IARS2 يرمز إلى إنزيم (Isoleucyl‑tRNA Synthetase 2) الميتوكوندري، والطفرات فيه تؤدي إلى متلازمة تشمل كتاركتًا خلقيًا ونقص هرمون النمو وفقدان سمع حسي عصبي واعتلال أعصاب.
How is the IARS2 genetic test performed and what sample is required?
كيف يتم إجراء اختبار جين IARS2 وما هي العينة المطلوبة؟
A blood or saliva sample is collected, then NGS analyzes the entire IARS2 gene for mutations. We accept whole blood (EDTA tube), extracted DNA, or a FTA card with a single drop of blood. Our laboratory uses next‑generation sequencing (NGS) with a clinically validated pipeline to detect single nucleotide variants, small insertions/deletions, and copy number changes. The process is minimally invasive, and home collection by a DHA‑licensed phlebotomist ensures comfort and cold‑chain integrity. يُجمع عينة دم أو لعاب بواسطة فريق تمريض منزلي، ثم تُحلل بتقنية التسلسل الجيني (NGS) للكشف عن الطفرات في كامل الجين.
What is the cost of the IARS2 test in UAE and does insurance cover it?
ما هي تكلفة اختبار IARS2 في الإمارات وهل يغطيه التأمين؟
The IARS2 Genetic Test costs 2800 AED, with insurance coverage verified through direct insurer billing. The total price includes analysis, interpretation, and a post‑test telephonic consultation. Most UAE health insurance plans cover diagnostic genetic testing when ordered by a physician. To verify your policy’s coverage instantly, send your Emirates ID and insurance card photo via WhatsApp to +971 54 548 8731; our team will confirm within the same working day. السعر 2800 درهمًا شاملة التحليل والتفسير والاستشارة الهاتفية. معظم وثائق التأمين تغطي الفحوصات الجينية التشخيصية؛ للتحقق أرسل صورة الهوية وبطاقة التأمين عبر واتساب.
Regulatory Compliance: This service is provided in accordance with Federal Decree‑Law No. 41 of 2024 on Medical Liability (Article 87), the UAE Child Digital Safety (CDS) Law 2026 for minors, and the UAE Personal Data Protection Law (PDPL). All patient data is encrypted and processed solely by DHA‑licensed professionals.
Quality Accreditation: ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139). Laboratory License No. 9834453.
Methodology: Next‑Generation Sequencing (NGS) with comprehensive bioinformatics analysis. sensitivity and specificity exceed 99.9% for the targeted regions.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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ISMS 27001:2022
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