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Test Price

2,800 AED

✅ Home Collection Available

DHA‑LICENSED FACILITY ISO 9001:2015

GATA4 Gene Atrioventricular Septal Defect Type 4 Next‑Generation Sequencing (NGS) Genetic Test in UAE

Executive Summary & Core Metrics

Premium Diagnostic Experience

  • Price: 2,800 AED – All‑inclusive cost with no hidden fees.
  • 99.9% Diagnostic Sensitivity – ISO‑accredited NGS lab processing with full gene coverage.
  • VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection – Available daily from 8 AM to 11 PM.
  • Post‑Test Clinical Guidance – Telephonic consultation with a DHA‑licensed clinical geneticist.
  • Direct Insurance Billing – WhatsApp verification at +971 54 548 8731.

Test Overview & Methodology

The GATA4 NGS test completely sequences the entire coding region and exon‑intron boundaries of the GATA4 gene, the primary molecular cause of atrioventricular septal defect type 4. It is the gold‑standard genetic confirmation for congenital heart disease families and guides cascade screening. Methodology uses next‑generation sequencing with Sanger confirmation for variant validation.

Feature Our Test (GATA4 Full Gene NGS) Single‑Variant Genotyping
Precision >99.9% analytical sensitivity & specificity for all variants Only detects known familial variant; misses novel mutations
Method Next‑Generation Sequencing (NGS) with Sanger confirmation PCR‑based targeted mutation analysis
Speed 3–4 Weeks (definitive result) 2–3 Weeks (limited scope)

Physician Insight & Safety Protocols

“A GATA4 test result must always be interpreted within the full clinical context – echocardiographic findings, family history, and genetic counseling are essential. A negative result does not exclude other genetic or environmental causes. Pre‑ and post‑test counseling by a qualified geneticist ensures appropriate risk communication and cascade testing.”

Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403

Advisory & Precautions

⚠️ IMPORTANT MEDICATION ADVISORY:

Do not discontinue any prescribed heart or anti‑coagulation medication without consulting your doctor. This test solely provides genetic information; it does not replace ongoing clinical management. Always inform your genetic counselor about all medications you are taking.

Safety Exclusion Criteria & Emergency Red Flags

Exclusion Criteria

  • Inability to provide valid informed consent (minors without legal guardian) or refusal of genetic counseling.
  • Non‑viable specimen (e.g., hemolyzed blood or degraded DNA).
  • Hemodynamically unstable patient – sample collection must be performed under hospital supervision; home phlebotomy is not permitted for acute cases.

Emergency Red Flags

If you experience sudden chest pain, severe dyspnea, or loss of consciousness, go to the nearest emergency department immediately. This test is an elective genetic investigation and not a substitute for urgent cardiac care.

Patient FAQ & Clinical Guidance

1. What is the GATA4 NGS test used for?

This DNA test identifies GATA4 mutations linked to atrioventricular septal defect type 4 for diagnosis. It helps cardiologists and clinical geneticists confirm a molecular cause in patients with congenital heart defects, enables family‑wide cascade screening, and supports reproductive risk assessment.

2. How is the test performed?

A simple blood sample or buccal swab is collected at home by our DHA‑licensed phlebotomist. The specimen is transported in a temperature‑controlled kit to our ISO‑certified genomics laboratory for NGS analysis, with full chain‑of‑custody documentation.

3. What do I need to prepare before the test?

You must attend a pre‑genetic counseling session to chart family pedigree before sample collection. Provide a detailed clinical history, including echocardiogram reports and surgeries. No fasting is required for standard blood draws.

UAE Regulatory & Data Privacy Adherence

Compliance & Trust Framework

This test and its associated data handling comply with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and informed consent adhere to Federal Decree‑Law No. 4 of 2016 on Medical Liability. All operations are conducted under the oversight of the Dubai Health Authority (DHA) and the corporate lab brand DNA Labs UAE.

DHA Facility License Number: 1143
Physical Address: Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE

Clinical & Logistical Metadata

Test Name GATA4 Gene Atrioventricular Septal Defect Type 4 Next‑Generation Sequencing (NGS) Genetic Test
Price (AED) 2,800 AED
Turnaround Time 3–4 Weeks
Sample Type / Matrix Whole Blood or Buccal Swab (VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection)
Methodology Used Next‑Generation Sequencing (NGS) with Sanger confirmation
ICD-10-CM Code Q21.2
LOINC Code 88827-5
DHA Facility License & Address License No. 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE

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