Test Price
2,800 AED✅ Home Collection Available
DNAJC19 Gene (3‑Methylglutaconic Aciduria Type 5) Genetic Test – 2,800 AED
Executive Summary & Core Metrics
99.9% Diagnostic Sensitivity via ISO 9001:2015 certified NGS processing – clinically validated against curated datasets. VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM) by DHA‑licensed phlebotomists. Post‑Test Clinical Guidance – telephone‑based interpretation by a genetic counsellor. Insurance Direct Billing Verification – WhatsApp +971 54 548 8731.
Test Overview & Methodology
This next‑generation sequencing test detects pathogenic variants in the DNAJC19 gene, confirming 3‑methylglutaconic aciduria type 5 – a rare recessive mitochondrial disorder. Our assay delivers DHA‑compliant results within 3–4 weeks on blood, extracted DNA, or FTA card samples.
| Parameter | This Test (DNAJC19 NGS) | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Methodology | Massively parallel NGS (full gene coverage, including deep intronic regions) | Sanger sequencing (targeted exon‑by‑exon) |
| Turnaround Time | 3–4 weeks | 4–6 weeks |
| Variant Detection | >99.9% for single‑nucleotide and copy‑number variants within the gene | ~99% for point mutations, limited CNV detection |
| Regulatory Acceptance | DHA compliant, ISO 9001:2015 | May require additional DHA approval for diagnostic use |
Physician Insight & Safety Protocols
“As a DHA‑licensed Consultant Medical Geneticist, I emphasise that a genetic test result is a piece of a larger clinical puzzle. A positive DNAJC19 finding must be interpreted alongside metabolic markers and family history, never in isolation. Confirmatory biochemical testing and counselling are essential.”
– Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory Note: Medication & Clinical Management
Medication Warning:
Do not discontinue any prescribed medication without consulting your treating physician. Genetic testing does not replace clinical management; sudden changes in diet or supplements may trigger metabolic decompensation.
Exclusion Criteria & Emergency Red Flags
- For Minors: Genetic testing of a child requires explicit, documented consent of a legal guardian. At‑home collection is only performed in the guardian’s presence. (Compliant with Federal Decree-Law No. 4 of 2016 on Medical Liability.)
- Acute Metabolic Crisis: If the individual is currently experiencing severe vomiting, lethargy, hypothermia, or seizures, do not proceed with elective genetic sampling – seek emergency medical care immediately.
- Coagulopathy/Anticoagulation: Patients on blood thinners or with known bleeding disorders must inform the phlebotomist; an FTA card (finger‑prick) may be substituted after clinical review.
- Unstable Clinical Status: Any acute illness requiring hospitalisation should be resolved before sample collection to avoid diagnostic interference.
If you or your child experience sudden decompensation – severe acidosis, loss of consciousness, or intractable seizures – call 998 or proceed to the nearest emergency department.
Patient FAQ & Clinical Guidance
1. What does a positive DNAJC19 gene test mean?
A positive result confirms a diagnosis of 3‑methylglutaconic aciduria type 5, requiring immediate metabolic management and genetic counselling for the entire family. This rare mitochondrial disorder may present with cardiomyopathy, neutropenia, and growth delay; early intervention is crucial.
2. How is the sample collected for this test in the UAE?
VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection ensures a painless blood draw or finger‑prick for an FTA card, with no hospital visit needed. The sample is transported in ISO‑certified cold‑chain conditions directly to our laboratory. Service available daily from 8 AM to 11 PM.
3. Is the cost covered by insurance in the UAE?
Most UAE insurance plans cover genetic testing when clinically indicated; we verify coverage via WhatsApp at +971 54 548 8731 before testing. A request form with ICD‑10 E71.115 from your physician often streamlines approval.
UAE Regulatory & Data Privacy Adherence
Data Protection & Confidentiality: All genetic and personal data are handled in strict compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient consent and clinical safety are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability.
DHA Licensed Facility: DNA Labs UAE operates under DHA Facility License Number 1143, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE.
Clinical & Logistical Metadata
| Test Name | DNAJC19 Gene Sequencing (3‑Methylglutaconic Aciduria Type 5) |
| Price (AED) | 2,800 |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Peripheral blood, Extracted DNA, or FTA card (dried blood spot) |
| Methodology Used | Next‑Generation Sequencing (NGS) – full gene coverage including deep intronic regions |
| ICD-10-CM Code | E71.115 |
| LOINC Code | 80866-8 |
| DHA Facility License & Laboratory Address | License: 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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التحقق من التغطية التأمينية
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ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians