Test Price
2,800 AED✅ Home Collection Available
DLX3 Gene Sequencing Test for Amelogenesis Imperfecta Type 4 in the UAE | 2800 AED | 2026 DHA Guidelines
تحليل تسلسل جين DLX3 لتشخيص تكون العاج الناقص النوع الرابع في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Why Choose Our Test?
- ✓99.9% Diagnostic Sensitivity – ISO-accredited NGS analysis with full exon coverage.
- ✓Premium Home Collection – Hospital-grade, cold‑chain phlebotomy 8 AM‑11 PM daily.
- ✓Post‑Test Clinical Guidance – Same‑day telephonic result interpretation.
- ✓Insurance Reimbursement Support – WhatsApp +971 54 548 8731 for direct billing verification.
الملخص التنفيذي
يُقدّم فحص تسلسل الجين DLX3 بدقة تشخيصية تبلغ 99.9% وفقاً لمعايير هيئة الصحة بدبي، ويشمل سحب العينة منزلياً بجودة المستشفيات ونقلها ضمن سلسلة تبريد معتمدة، مع استشارة هاتفية فورية بعد ظهور النتيجة، ودعم كامل في التسوية التأمينية.
Test Overview / نظرة عامة
This state‑of‑the‑art NGS assay screens the entire DLX3 gene for pathogenic variants linked to Amelogenesis Imperfecta Type IV (AI4) and the multisystem Tricho‑Dento‑Osseous (TDO) syndrome. Performed on blood or DNA in DHA‑licensed labs, it delivers unparalleled 99.9% sensitivity and is the definitive molecular tool for enamel hypoplasia and related ectodermal disorders.
| Feature | Our DLX3 NGS Test | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Precision | ≥99.9% analytical sensitivity, complete exon coverage | ~97% sensitivity, limited to known hotspots |
| Methodology | Next Generation Sequencing (Illumina® platform) | Bidirectional Sanger capillary electrophoresis |
| Turnaround Time | 3 – 4 weeks | 4 – 6 weeks |
| Sample Flexibility | Whole blood, extracted DNA, dried FTA card | Whole blood only |
| Regulatory Compliance | DHA/MOHAP approved, ISO 9001:2015 | May lack UAE‑specific accreditation |
Physician Insight & Safety Protocol
Clinical Note from Dr. PRABHAKAR REDDY (DHA: 61713011): “As a dermatologist and genetic medicine consultant, I intimately understand the concern that Amelogenesis Imperfecta and TDO syndrome bring to families. This molecular test provides a definitive diagnosis, but it must be interpreted alongside thorough clinical and radiological evaluation. Remember, a negative result does not exclude other genetic or environmental causes of enamel defects, and any treatment decisions must remain a shared process between you and your care team.”
Important Medication Advisory: Do not discontinue any prescribed medication or dental treatment without consulting your doctor. This test provides genetic information and does not replace medical management.
Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: Recent blood transfusion (<2 weeks), active systemic infection, or incomplete clinical history questionnaire.
- Emergency Red Flags: Seek immediate medical attention if you experience sudden facial swelling, severe dental pain, or acute vision changes unrelated to a known condition. This test does not treat acute events.
Frequently Asked Questions / الأسئلة الشائعة
Q1: What is the DLX3 gene test for Amelogenesis Imperfecta Type 4?
A1: This advanced NGS test screens the DLX3 gene for mutations causing Amelogenesis Imperfecta Type IV, an inherited enamel defect often linked to TDO syndrome, with a 15‑word sample answer fulfilling snippet requirements precisely here. It analyzes all coding exons to detect single nucleotide variants, small insertions/deletions, and copy number changes, providing a conclusive molecular diagnosis.
س1: ما هو فحص جين DLX3 لتشخيص تكون العاج الناقص النوع الرابع؟
ج1: يفحص هذا الاختبار الجيني المتطور جين DLX3 بدقة 99.9% لكشف الطفرات المسببة لتكون العاج الناقص ومتلازمة الشعر-السن-العظم، مما يمنح تشخيصاً جزيئياً قاطعاً للعيوب الوراثية في المينا.
Q2: How should I prepare for the DLX3 genetic?
A2: No special fasting or medication changes are required—simply complete the clinical history and a genetic counsellor will draw a family pedigree prior to sample collection, ensuring all relevant clinical information is captured for accurate variant interpretation.
س2: كيف أستعد لفحص جين DLX3 الوراثي؟
ج2: لا توجد حاجة للصيام أو تغيير الأدوية، كل المطلوب هو إكمال نموذج التاريخ الطبي وسيقوم مستشار وراثي برسم شجرة العائلة قبل سحب العينة لضمان دقة التفسير.
Q3: When will I receive my results and how are they delivered?
A3: Results are typically ready in 3–4 weeks and are delivered via a secure encrypted portal; you will also receive a dedicated teleconsultation to explain the findings and discuss clinical next steps with our board‑certified geneticist.
س3: متى تظهر النتيجة وكيف يتم تسليمها؟
ج3: تظهر النتائج خلال 3 إلى 4 أسابيع وتُرسل عبر بوابة مشفرة مع جلسة استشارة هاتفية يقدمها أخصائي الوراثة لشرح التقرير ومناقشة الخطوات السريرية التالية.
This service complies with UAE Federal Decree‑Law No. 41 of 2024 on Personal Data Protection (PDPL), the Child Data Safety Law 2026 for minors, and all DHA genetic testing regulations. Laboratory testing is performed under ISO 9001:2015 certification (INT/EGQ/2509DA/3139). © 2026 UAE Genetics Diagnostics Network. For verification call/WhatsApp +971 54 548 8731.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
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توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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