Test Price
2,800 AED✅ Home Collection Available
DISP1 Gene Craniofacial & Neurodevelopmental Abnormalities Genetic Test | 2800 AED | DHA Licensed, Dubai, UAE
Executive Summary & Core Metrics
- Diagnostic Accuracy: 99.9% sensitivity via ISO 9001:2015 accredited next-generation sequencing (NGS) genomic processing for the DISP1 gene.
- Logistics & Collection: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM across all UAE emirates.
- Post-Test Support: DHA-licensed genetic counsellor provides telephonic result interpretation and clinical guidance within 72 hours of report delivery.
- Insurance & Billing: Direct billing verification and pre-authorisation support via WhatsApp at +971 54 548 8731.
Key Clinical Metrics
- Test Type: Single-gene sequencing with CNV detection
- Platform: Illumina NGS, whole coding region ±20 bp
- Turnaround Time: 3–4 weeks from sample receipt
- Specimen: Peripheral whole blood (2–5 mL in EDTA tube)
- DHA Facility License: 1143, Dubai Healthcare City
Test Overview & Methodology
This state-of-the-art NGS test screens the entire DISP1 gene for pathogenic variants linked to craniofacial malformations (e.g., holoprosencephaly spectrum) and neurodevelopmental delay. The assay detects single nucleotide variants (SNVs), small insertions/deletions (indels), and copy number variants (CNVs) across all coding exons and flanking intronic regions (±20 bp).
| Feature | Our Test (NGS) | Closest Alternative (Sanger) |
|---|---|---|
| Precision & Coverage | Full coding region ±20 bp; detects SNVs, indels, CNVs | Single exon sequencing; limited variant coverage |
| Methodology | Next-Generation Sequencing (NGS) on Illumina platform | Capillary electrophoresis (Sanger dideoxy) |
| Turnaround Time | 3–4 Weeks | 6–8 Weeks |
Physician Insight & Safety Protocols
"Molecular confirmation of DISP1 variants provides a critical diagnostic anchor for families navigating craniofacial and neurodevelopmental presentations. However, these results must always be interpreted alongside a comprehensive clinical evaluation by a paediatric neurologist or clinical geneticist. The test is a powerful tool — not a standalone diagnosis."
— Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403
Pre-Test Advisory
Important Clinical Guidance Before Testing
This genetic test is intended for diagnostic confirmation and risk assessment only. It does not replace a full clinical workup, imaging studies, or specialist consultation. Patients and guardians should review all benefits, limitations, and potential implications of genetic testing with a qualified healthcare provider before proceeding. Results may have implications for family members; cascade testing counselling is recommended.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Patients unable to provide informed consent. Minors must have documented guardian consent per UAE Federal Decree-Law No. 4 of 2016 on Medical Liability.
- Exclusion: Active bleeding disorder not medically cleared for venipuncture; sample collected in non-standard or unlabelled container.
- Exclusion: Previous allogeneic bone marrow transplant (may cause donor DNA interference in genetic analysis).
- 🚨 Red Flag: If the patient experiences acute neurological deterioration (prolonged seizure, loss of consciousness, severe developmental regression) before receiving results, seek emergency medical care immediately.
Patient FAQ & Clinical Guidance
1. What does the DISP1 genetic test detect?
This NGS-based test reads the entire DISP1 gene to identify pathogenic variants that cause craniofacial anomalies such as holoprosencephaly and associated neurodevelopmental disorders. It is the most comprehensive single-gene confirmatory tool currently available in the UAE.
2. How long does the test take and can it be performed at home?
Results are delivered within 3 to 4 weeks after sample receipt. Yes, our hospital-grade VIP Mobile Phlebotomy service sends a certified phlebotomist to your home anywhere in the UAE between 8 AM and 11 PM — no clinic visit required. Samples are transported under temperature-controlled cold-chain logistics.
3. Is this test covered by UAE health insurance?
Many UAE insurance providers cover genetic testing when pre-authorised by a specialist. We verify your coverage via a quick WhatsApp message and handle direct billing where applicable. Contact +971 54 548 8731 for a confirmation within 24 hours.
UAE Regulatory & Data Privacy Adherence
Healthcare Compliance & Data Protection Framework
DNA Labs UAE operates under DHA Facility License No. 1143, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE. All genetic testing services comply with:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) — governing the collection, processing, and storage of genetic and health data with explicit patient consent.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields — regulating the secure handling of electronic health records and digital clinical data.
- Federal Decree-Law No. 4 of 2016 on Medical Liability — ensuring patient safety, informed consent, and clinical accountability throughout the testing pathway.
ISO 9001:2015 certification (certificate no. INT/EGQ/2509DA/3139) underpins our quality management system. All genetic results are released only to the requesting physician or authorised patient portal with multi-factor authentication.
Clinical & Logistical Metadata
| Test Name | DISP1 Gene Craniofacial & Neurodevelopmental Abnormalities Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood (2–5 mL in EDTA tube) |
| Methodology Used | Next-Generation Sequencing (NGS) on Illumina Platform |
| ICD-10-CM Code | Q04.2, Q87.0, Z15.89 |
| LOINC Code | 76679-8 |
| DHA Facility License & Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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ISMS 27001:2022
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All reports reviewed by DHA-Certified physicians