Test Price
2,800 AED✅ Home Collection Available
DIAPH3 Gene Auditory Neuropathy (Autosomal Dominant) Genetic Test in UAE | 2800 AED | 2026 DHA-Endorsed
تحليل جين DIAPH3 للاعتلال العصبي السمعي السائد جسديًا في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
ملخص تنفيذي: ضمان الدقة والامتثال الصحي
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified NGS processing.
- Premium Logistics: Paid Hospital-Grade Home Collection with ISO Certified Cold-Chain transport and VIP Mobile Phlebotomy.
- Clinical Guidance: Complimentary post‑test telephonic clinical guidance with a DHA‑licensed genetic counsellor.
- Insurance: Direct Billing Verification & Pre‑Approval via WhatsApp +971 54 548 8731.
تنبيه: جميع التحليلات مطابقة للمرسوم بقانون اتحادي رقم 41 لسنة 2024 وقانون حماية بيانات المرضى (PDPL) الإماراتي.
Comprehensive NGS‑Based Diagnosis of Auditory Neuropathy
The DIAPH3 gene sequencing test delivers precise detection of autosomal dominant mutations causing auditory neuropathy spectrum disorder (ANSD), empowering early clinical intervention and family‑centred genetic counselling. يُعد هذا التحليل الأكثر شمولية في الإمارات لتشخيص طيف الاعتلال العصبي السمعي السائد وراثيًا.
| Feature | Our NGS Test (DIAPH3) | Conventional Sanger Sequencing |
|---|---|---|
| Technology | Next‑Generation Sequencing (Illumina®) | Sanger (single‑amplicon) |
| Analytical Sensitivity | >99.9% for SNVs & small indels across entire coding region | >99% but only for targeted exons |
| Turnaround Time | 3 to 4 Weeks | 6–10 Weeks |
| Clinical Utility | Full diagnostic & carrier screening, haplotype insights | Limited to known familial mutation |
| Regulatory Endorsement | DHA/MOHAP‑recognised, ISO 9001:2015 | May lack UAE accreditation |
Physician Insight & Safety Protocol
Dr. PRABHAKAR REDDY (DHA License 61713011), Consultant Otolaryngologist, notes:
"This gene test is a cornerstone for families with dominant auditory neuropathy, yet its result must be interpreted alongside audiometric thresholds and neurological assessment. I strongly advise that you never self‑diagnose or modify hearing aid or medication regimens without professional consultation. The report empowers personalised management, but only within a full clinical context."
Do not discontinue prescribed medication without consulting your doctor.
Safety Exclusion Criteria & Emergency Red Flags
- Lack of clinical suspicion of syndromic/non‑syndromic auditory neuropathy or absence of a documented family history of early‑onset hearing loss.
- Patients or guardians unable to give informed consent (mandatory pre‑test genetic counselling).
- Acute onset of sudden hearing loss, severe tinnitus, vertigo, or focal neurological deficits within the last 72 hours – seek emergency ENT evaluation immediately.
- Known contraindications to venipuncture or dried blood spot collection in neonates.
Frequently Asked Clinical Questions
What is the DIAPH3 gene test and why is it recommended?
ما هو تحليل جين DIAPH3 ولماذا يُنصح بإجرائه؟
This DIAPH3 gene sequencing test identifies mutations causing autosomal dominant auditory neuropathy, enabling precise early diagnosis and family planning. The analysis covers all coding exons of DIAPH3 using high‑coverage NGS, confirming the genetic aetiology behind lifelong sensorineural hearing loss that typically presents at birth or early childhood. Results guide audiological intervention, cochlear implant candidacy, and recurrence risk counselling for relatives.
يحدّد هذا التحليل الطفرات المسبّبة للاعتلال العصبي السمعي السائد جسديًا، مما يسمح بالتشخيص المبكر الدقيق ووضع خطة عائلية مستنيرة.
How should I prepare for the DIAPH3 NGS test?
كيف أستعد لفحص جين DIAPH3 بتقنية التسلسل الجيني المتقدم؟
A mandatory pre‑ genetic counselling session collects your family pedigree and ensures you understand the implications of autosomal dominant inheritance. No fasting is required, but you must provide a detailed clinical history of hearing loss, previous audiology reports, and a list of current medications. For infants, a cord blood or heel‑prick FTA card is acceptable; adults can opt for blood draw or buccal swab.
جلسة استشارة وراثية إلزامية تجمع تاريخ العائلة للتأكد من فهمك لطبيعة الوراثة السائدة قبل سحب العينة.
What does a positive DIAPH3 result mean for my family?
ماذا تعني النتيجة الإيجابية لجين DIAPH3 بالنسبة لعائلتي؟
A positive result confirms the genetic cause of auditory neuropathy and carries a 50% recurrence risk in each pregnancy for an affected parent. Cascade testing can then be offered to at‑risk relatives. Genetic counsellors will interpret the variant’s pathogenicity based on ACMG guidelines and discuss reproductive options such as preimplantation genetic diagnosis (PGD) if desired.
النتيجة الإيجابية تؤكد السبب الجيني وتحمل خطر تكرار بنسبة 50% لكل حمل للوالد المصاب، مع إمكانية فحص الأقارب المعرضين للخطر.
This service is provided under UAE Federal Decree-Law No. 41 of 2024 (Medical Liability), the 2026 CDS Law for Minors, and the UAE Personal Data Protection Law (PDPL).
Licensed Facility: 9834453 | ISO 9001:2015 Certificate INT/EGQ/2509DA/3139 | All results reviewed by DHA‑licensed clinicians.
Direct WhatsApp assistance: +971 54 548 8731
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Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
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All reports reviewed by DHA-Certified physicians